diprophylline-5482 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the diprophylline-5482 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ASCL1 achaete-scute family bHLH transcription factor 1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BAIAP3 BAI1-associated protein 3
BTBD7 BTB (POZ) domain containing 7
BTF3P11 basic transcription factor 3 pseudogene 11
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CASP4 caspase 4, apoptosis-related cysteine peptidase
CCNO cyclin O
CD247 CD247 molecule
CD52 CD52 molecule
CD58 CD58 molecule
CD79A CD79a molecule, immunoglobulin-associated alpha
CEP112 centrosomal protein 112kDa
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
COPE coatomer protein complex, subunit epsilon
CPNE7 copine VII
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CRYGB crystallin, gamma B
CSF1 colony stimulating factor 1 (macrophage)
CSF1R colony stimulating factor 1 receptor
CXCL8 chemokine (C-X-C motif) ligand 8
DNAL4 dynein, axonemal, light chain 4
DRD2 dopamine receptor D2
ELP6 elongator acetyltransferase complex subunit 6
EVI5 ecotropic viral integration site 5
EXOC7 exocyst complex component 7
GAL galanin/GMAP prepropeptide
GAP43 growth associated protein 43
GAS7 growth arrest-specific 7
GPC4 glypican 4
GPR25 G protein-coupled receptor 25
GRM4 glutamate receptor, metabotropic 4
GSTP1 glutathione S-transferase pi 1
HFE hemochromatosis
HLA-DMA major histocompatibility complex, class II, DM alpha
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IFITM1 interferon induced transmembrane protein 1
IGLJ3 immunoglobulin lambda joining 3
IL4R interleukin 4 receptor
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
IRF9 interferon regulatory factor 9
ISG15 ISG15 ubiquitin-like modifier
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KDM8 lysine (K)-specific demethylase 8
KLK8 kallikrein-related peptidase 8
LINC00260 long intergenic non-protein coding RNA 260
LRP12 low density lipoprotein receptor-related protein 12
LSP1 lymphocyte-specific protein 1
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAN2A2 mannosidase, alpha, class 2A, member 2
MANBA mannosidase, beta A, lysosomal
MTMR2 myotubularin related protein 2
NFX1 nuclear transcription factor, X-box binding 1
NOL12 nucleolar protein 12
NPHP1 nephronophthisis 1 (juvenile)
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OGFR opioid growth factor receptor
POU2F2 POU class 2 homeobox 2
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRPF31 pre-mRNA processing factor 31
RALGDS ral guanine nucleotide dissociation stimulator
RASL10A RAS-like, family 10, member A
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RBM26 RNA binding motif protein 26
RERE arginine-glutamic acid dipeptide (RE) repeats
RHOT2 ras homolog family member T2
RIMS1 regulating synaptic membrane exocytosis 1
SCG2 secretogranin II
SIRPB1 signal-regulatory protein beta 1
SIRT3 sirtuin 3
SIX3 SIX homeobox 3
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT5B signal transducer and activator of transcription 5B
SULT4A1 sulfotransferase family 4A, member 1
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TAOK2 TAO kinase 2
TMPRSS3 transmembrane protease, serine 3
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRIM25 tripartite motif containing 25
TSSK2 testis-specific serine kinase 2
UNC119 unc-119 homolog (C. elegans)
VAV2 vav 2 guanine nucleotide exchange factor
VN1R1 vomeronasal 1 receptor 1
WDR76 WD repeat domain 76
WHSC1 Wolf-Hirschhorn syndrome candidate 1
ZC3H13 zinc finger CCCH-type containing 13
ZNF204P zinc finger protein 204, pseudogene

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
AARSD1 alanyl-tRNA synthetase domain containing 1
ACAD10 acyl-CoA dehydrogenase family, member 10
ADGRG2 adhesion G protein-coupled receptor G2
ADTRP androgen-dependent TFPI-regulating protein
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
ARSB arylsulfatase B
ASPHD1 aspartate beta-hydroxylase domain containing 1
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
C6ORF47 chromosome 6 open reading frame 47
CCNJ cyclin J
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CENPO centromere protein O
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CIR1 corepressor interacting with RBPJ, 1
CLCN2 chloride channel, voltage-sensitive 2
CRLF1 cytokine receptor-like factor 1
CTC1 CTS telomere maintenance complex component 1
CXADR coxsackie virus and adenovirus receptor
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DGKE diacylglycerol kinase, epsilon 64kDa
EAF2 ELL associated factor 2
ELOVL4 ELOVL fatty acid elongase 4
ENO2 enolase 2 (gamma, neuronal)
ERCC5 excision repair cross-complementation group 5
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ERN2 endoplasmic reticulum to nucleus signaling 2
EXOC5 exocyst complex component 5
F3 coagulation factor III (thromboplastin, tissue factor)
FBXO31 F-box protein 31
FURIN furin (paired basic amino acid cleaving enzyme)
GSTCD glutathione S-transferase, C-terminal domain containing
IL17RA interleukin 17 receptor A
IPO13 importin 13
IRAK4 interleukin-1 receptor-associated kinase 4
IRF6 interferon regulatory factor 6
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KDM5C lysine (K)-specific demethylase 5C
KIF13B kinesin family member 13B
KLC2 kinesin light chain 2
LAMA3 laminin, alpha 3
LAMB2 laminin, beta 2 (laminin S)
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRP2 low density lipoprotein receptor-related protein 2
LY6G5C lymphocyte antigen 6 complex, locus G5C
MAPKBP1 mitogen-activated protein kinase binding protein 1
MBNL3 muscleblind-like splicing regulator 3
MDN1 MDN1, midasin homolog (yeast)
MTERF4 mitochondrial transcription termination factor 4
NRGN neurogranin (protein kinase C substrate, RC3)
NUPL2 nucleoporin like 2
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLEKHO2 pleckstrin homology domain containing, family O member 2
POLL polymerase (DNA directed), lambda
POPDC3 popeye domain containing 3
PRODH proline dehydrogenase (oxidase) 1
PRSS22 protease, serine, 22
PTDSS2 phosphatidylserine synthase 2
PYCRL pyrroline-5-carboxylate reductase-like
RASA2 RAS p21 protein activator 2
RFTN1 raftlin, lipid raft linker 1
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNF123 ring finger protein 123
RNH1 ribonuclease/angiogenin inhibitor 1
RPAP1 RNA polymerase II associated protein 1
RPH3AL rabphilin 3A-like (without C2 domains)
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
SCAI suppressor of cancer cell invasion
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SHARPIN SHANK-associated RH domain interactor
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SLC46A3 solute carrier family 46, member 3
SP140L SP140 nuclear body protein-like
SPINK5 serine peptidase inhibitor, Kazal type 5
STK16 serine/threonine kinase 16
STX1A syntaxin 1A (brain)
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SUSD4 sushi domain containing 4
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
THAP7 THAP domain containing 7
TMEM62 transmembrane protein 62
TNNT1 troponin T type 1 (skeletal, slow)
TRAIP TRAF interacting protein
USB1 U6 snRNA biogenesis 1
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae)
WDR4 WD repeat domain 4
WLS wntless Wnt ligand secretion mediator
ZC3H12A zinc finger CCCH-type containing 12A
ZC3H3 zinc finger CCCH-type containing 3
ZNF34 zinc finger protein 34
ZNF41 zinc finger protein 41
ZNF74 zinc finger protein 74
ZNF862 zinc finger protein 862