dipyridamole-2017 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the dipyridamole-2017 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ACAN aggrecan
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
ADRBK1 adrenergic, beta, receptor kinase 1
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa
BCL3 B-cell CLL/lymphoma 3
C1QTNF1 C1q and tumor necrosis factor related protein 1
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CCPG1 cell cycle progression 1
CD38 CD38 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD58 CD58 molecule
CFLAR CASP8 and FADD-like apoptosis regulator
CREM cAMP responsive element modulator
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CYLD cylindromatosis (turban tumor syndrome)
CYTH1 cytohesin 1
DDAH2 dimethylarginine dimethylaminohydrolase 2
DOCK4 dedicator of cytokinesis 4
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ETV7 ets variant 7
FER1L4 fer-1-like family member 4, pseudogene (functional)
FLNB filamin B, beta
FOS FBJ murine osteosarcoma viral oncogene homolog
FTH1 ferritin, heavy polypeptide 1
G0S2 G0/G1 switch 2
GBP2 guanylate binding protein 2, interferon-inducible
ISG15 ISG15 ubiquitin-like modifier
ITGB7 integrin, beta 7
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KLHL9 kelch-like family member 9
KYNU kynureninase
LENEP lens epithelial protein
LIG3 ligase III, DNA, ATP-dependent
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LTB4R leukotriene B4 receptor
MAST3 microtubule associated serine/threonine kinase 3
MBP myelin basic protein
MOB3B MOB kinase activator 3B
MT1F metallothionein 1F
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MVK mevalonate kinase
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NEBL nebulette
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NHEJ1 nonhomologous end-joining factor 1
NINJ1 ninjurin 1
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
PBX2 pre-B-cell leukemia homeobox 2
PIDD1 p53-induced death domain protein 1
PLAUR plasminogen activator, urokinase receptor
PLSCR1 phospholipid scramblase 1
PLXNC1 plexin C1
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
PPAP2A phosphatidic acid phosphatase type 2A
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PRDX2 peroxiredoxin 2
QTRT1 queuine tRNA-ribosyltransferase 1
RAB11B RAB11B, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RARA retinoic acid receptor, alpha
RGS2 regulator of G-protein signaling 2
RIN3 Ras and Rab interactor 3
RNF170 ring finger protein 170
RXRA retinoid X receptor, alpha
SAT1 spermidine/spermine N1-acetyltransferase 1
SBNO2 strawberry notch homolog 2 (Drosophila)
SDC2 syndecan 2
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SH2D2A SH2 domain containing 2A
SH3BP2 SH3-domain binding protein 2
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SPN sialophorin
SPPL2B signal peptide peptidase like 2B
SRPK3 SRSF protein kinase 3
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TBC1D22A TBC1 domain family, member 22A
TCF3 transcription factor 3
TESK1 testis-specific kinase 1
THBS1 thrombospondin 1
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TRAC T cell receptor alpha constant
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TREM1 triggering receptor expressed on myeloid cells 1
TTC3 tetratricopeptide repeat domain 3
TTLL4 tubulin tyrosine ligase-like family member 4
TULP3 tubby like protein 3
USF2 upstream transcription factor 2, c-fos interacting
VAC14 Vac14 homolog (S. cerevisiae)
WDR48 WD repeat domain 48
ZMYM5 zinc finger, MYM-type 5
ZNF224 zinc finger protein 224

decreased expression

Symbol Name
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
ACTL6A actin-like 6A
ADAP2 ArfGAP with dual PH domains 2
AHR aryl hydrocarbon receptor
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ARHGAP10 Rho GTPase activating protein 10
ASUN asunder spermatogenesis regulator
ATF1 activating transcription factor 1
AZI2 5-azacytidine induced 2
BAHD1 bromo adjacent homology domain containing 1
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BCORL1 BCL6 corepressor-like 1
C14ORF169 chromosome 14 open reading frame 169
C17ORF85 chromosome 17 open reading frame 85
C5ORF28 chromosome 5 open reading frame 28
C6ORF47 chromosome 6 open reading frame 47
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCDC47 coiled-coil domain containing 47
CCNA1 cyclin A1
CD302 CD302 molecule
CDK8 cyclin-dependent kinase 8
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CISH cytokine inducible SH2-containing protein
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DRAM1 DNA-damage regulated autophagy modulator 1
EDEM2 ER degradation enhancer, mannosidase alpha-like 2
FAM160B2 family with sequence similarity 160, member B2
FCHSD2 FCH and double SH3 domains 2
FN3KRP fructosamine 3 kinase related protein
FYCO1 FYVE and coiled-coil domain containing 1
GATAD2A GATA zinc finger domain containing 2A
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GMEB1 glucocorticoid modulatory element binding protein 1
GTF2IRD1 GTF2I repeat domain containing 1
GUSBP3 glucuronidase, beta pseudogene 3
HIRA histone cell cycle regulator
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HP haptoglobin
IMPACT impact RWD domain protein
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
INO80D INO80 complex subunit D
KAT2A K(lysine) acetyltransferase 2A
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KCTD5 potassium channel tetramerization domain containing 5
KIAA0753 KIAA0753
LAMP5 lysosomal-associated membrane protein family, member 5
LMNB1 lamin B1
LRP3 low density lipoprotein receptor-related protein 3
MAGOHB mago-nashi homolog B (Drosophila)
MED4 mediator complex subunit 4
MFSD12 major facilitator superfamily domain containing 12
MFSD5 major facilitator superfamily domain containing 5
MICB MHC class I polypeptide-related sequence B
MPP1 membrane protein, palmitoylated 1, 55kDa
MRPL52 mitochondrial ribosomal protein L52
MUC3A mucin 3A, cell surface associated
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NIP7 NIP7, nucleolar pre-rRNA processing protein
OPHN1 oligophrenin 1
OVGP1 oviductal glycoprotein 1, 120kDa
PCSK7 proprotein convertase subtilisin/kexin type 7
PEMT phosphatidylethanolamine N-methyltransferase
PHACTR4 phosphatase and actin regulator 4
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PNRC1 proline-rich nuclear receptor coactivator 1
POU2F1 POU class 2 homeobox 1
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
RAB5B RAB5B, member RAS oncogene family
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
RRP1 ribosomal RNA processing 1
RWDD3 RWD domain containing 3
SACM1L SAC1 suppressor of actin mutations 1-like (yeast)
SCYL2 SCY1-like 2 (S. cerevisiae)
SDHAF3 succinate dehydrogenase complex assembly factor 3
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SIRT1 sirtuin 1
SIRT6 sirtuin 6
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLMO2 slowmo homolog 2 (Drosophila)
SPON2 spondin 2, extracellular matrix protein
SPP1 secreted phosphoprotein 1
SREBF1 sterol regulatory element binding transcription factor 1
TBCCD1 TBCC domain containing 1
TM7SF3 transmembrane 7 superfamily member 3
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRHDE thyrotropin-releasing hormone degrading enzyme
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UBXN2B UBX domain protein 2B
UNKL unkempt family zinc finger-like
USP25 ubiquitin specific peptidase 25
WDR82 WD repeat domain 82
ZNF140 zinc finger protein 140