| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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194 genes differentially expressed following the dirithromycin-1712 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACSBG2 | acyl-CoA synthetase bubblegum family member 2 |
| ADAM12 | ADAM metallopeptidase domain 12 |
| ADRA2B | adrenoceptor alpha 2B |
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
| ALOXE3 | arachidonate lipoxygenase 3 |
| ATF6B | activating transcription factor 6 beta |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
| BIRC7 | baculoviral IAP repeat containing 7 |
| BMP2K | BMP2 inducible kinase |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CA12 | carbonic anhydrase XII |
| CACFD1 | calcium channel flower domain containing 1 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit |
| CALB2 | calbindin 2 |
| CEND1 | cell cycle exit and neuronal differentiation 1 |
| CHN2 | chimerin 2 |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLTA | clathrin, light chain A |
| CNTFR | ciliary neurotrophic factor receptor |
| CNTNAP1 | contactin associated protein 1 |
| COL18A1 | collagen, type XVIII, alpha 1 |
| COMT | catechol-O-methyltransferase |
| CORT | cortistatin |
| CPM | carboxypeptidase M |
| CPNE7 | copine VII |
| CXCL12 | chemokine (C-X-C motif) ligand 12 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 |
| DNAH7 | dynein, axonemal, heavy chain 7 |
| DSPP | dentin sialophosphoprotein |
| DUSP26 | dual specificity phosphatase 26 (putative) |
| EFR3B | EFR3 homolog B (S. cerevisiae) |
| FBRS | fibrosin |
| FOXC1 | forkhead box C1 |
| FSCN1 | fascin actin-bundling protein 1 |
| GIPC1 | GIPC PDZ domain containing family, member 1 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| HAB1 | B1 for mucin |
| HAMP | hepcidin antimicrobial peptide |
| HAND1 | heart and neural crest derivatives expressed 1 |
| IGHA1 | immunoglobulin heavy constant alpha 1 |
| IHH | indian hedgehog |
| IL2RB | interleukin 2 receptor, beta |
| IQCC | IQ motif containing C |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KIR2DL5A | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A |
| L1TD1 | LINE-1 type transposase domain containing 1 |
| LILRA4 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 |
| LIMS2 | LIM and senescent cell antigen-like domains 2 |
| LINC00312 | long intergenic non-protein coding RNA 312 |
| MIIP | migration and invasion inhibitory protein |
| MMP25 | matrix metallopeptidase 25 |
| MOSPD3 | motile sperm domain containing 3 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming |
| MXRA8 | matrix-remodelling associated 8 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NIPAL2 | NIPA-like domain containing 2 |
| NPEPL1 | aminopeptidase-like 1 |
| PADI1 | peptidyl arginine deiminase, type I |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) |
| PKP3 | plakophilin 3 |
| PLCG1 | phospholipase C, gamma 1 |
| PLK3 | polo-like kinase 3 |
| PPP5C | protein phosphatase 5, catalytic subunit |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRODH2 | proline dehydrogenase (oxidase) 2 |
| PTGES | prostaglandin E synthase |
| PTN | pleiotrophin |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) |
| RAB2A | RAB2A, member RAS oncogene family |
| RPL7 | ribosomal protein L7 |
| RXRA | retinoid X receptor, alpha |
| SALL2 | spalt-like transcription factor 2 |
| SCN5A | sodium channel, voltage gated, type V alpha subunit |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| TLE4 | transducin-like enhancer of split 4 |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TMEM212 | transmembrane protein 212 |
| TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) |
| TRAPPC9 | trafficking protein particle complex 9 |
| TSPAN9 | tetraspanin 9 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| TYR | tyrosinase |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) |
| VGF | VGF nerve growth factor inducible |
| WFDC8 | WAP four-disulfide core domain 8 |
| ZFHX2 | zinc finger homeobox 2 |
| ZMYND8 | zinc finger, MYND-type containing 8 |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ABT1 | activator of basal transcription 1 |
| AES | amino-terminal enhancer of split |
| ANAPC15 | anaphase promoting complex subunit 15 |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| ARL4A | ADP-ribosylation factor-like 4A |
| ARRB2 | arrestin, beta 2 |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| AVEN | apoptosis, caspase activation inhibitor |
| BARD1 | BRCA1 associated RING domain 1 |
| BCL7C | B-cell CLL/lymphoma 7C |
| BLVRB | biliverdin reductase B |
| BYSL | bystin-like |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 |
| CAPN15 | calpain 15 |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CCNL2 | cyclin L2 |
| CDCA8 | cell division cycle associated 8 |
| CFL1 | cofilin 1 (non-muscle) |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLDN15 | claudin 15 |
| COMMD9 | COMM domain containing 9 |
| CORO7 | coronin 7 |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CSTF2 | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa |
| DBF4B | DBF4 zinc finger B |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DHRS7B | dehydrogenase/reductase (SDR family) member 7B |
| DYRK4 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 |
| EMC9 | ER membrane protein complex subunit 9 |
| ENDOG | endonuclease G |
| ENO2 | enolase 2 (gamma, neuronal) |
| FZD2 | frizzled class receptor 2 |
| GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 |
| GOLPH3L | golgi phosphoprotein 3-like |
| HIST1H2BE | histone cluster 1, H2be |
| HIST1H2BF | histone cluster 1, H2bf |
| HMGB3P1 | high mobility group box 3 pseudogene 1 |
| ITPA | inosine triphosphatase (nucleoside triphosphate pyrophosphatase) |
| KEAP1 | kelch-like ECH-associated protein 1 |
| KLF13 | Kruppel-like factor 13 |
| KRBOX4 | KRAB box domain containing 4 |
| LIG1 | ligase I, DNA, ATP-dependent |
| MAN2B1 | mannosidase, alpha, class 2B, member 1 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 |
| MPV17 | MpV17 mitochondrial inner membrane protein |
| MRPL4 | mitochondrial ribosomal protein L4 |
| MSRB1 | methionine sulfoxide reductase B1 |
| MT1HL1 | metallothionein 1H-like 1 |
| MTG1 | mitochondrial ribosome-associated GTPase 1 |
| MYLIP | myosin regulatory light chain interacting protein |
| NADSYN1 | NAD synthetase 1 |
| NFE2 | nuclear factor, erythroid 2 |
| NSUN5P1 | NOP2/Sun domain family, member 5 pseudogene 1 |
| NUP93 | nucleoporin 93kDa |
| NVL | nuclear VCP-like |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| ORC1 | origin recognition complex, subunit 1 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| PAGR1 | PAXIP1 associated glutamate-rich protein 1 |
| PAK1IP1 | PAK1 interacting protein 1 |
| PAQR4 | progestin and adipoQ receptor family member IV |
| PCTP | phosphatidylcholine transfer protein |
| PDSS2 | prenyl (decaprenyl) diphosphate synthase, subunit 2 |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit |
| PSKH1 | protein serine kinase H1 |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| RAB4B | RAB4B, member RAS oncogene family |
| RABEPK | Rab9 effector protein with kelch motifs |
| RBM10 | RNA binding motif protein 10 |
| RBM14 | RNA binding motif protein 14 |
| RHOH | ras homolog family member H |
| RNF144A | ring finger protein 144A |
| RNF167 | ring finger protein 167 |
| RWDD2B | RWD domain containing 2B |
| SAC3D1 | SAC3 domain containing 1 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SMG9 | SMG9 nonsense mediated mRNA decay factor |
| SNX6 | sorting nexin 6 |
| STRA13 | stimulated by retinoic acid 13 |
| TAF12 | TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa |
| TARS2 | threonyl-tRNA synthetase 2, mitochondrial (putative) |
| TEX264 | testis expressed 264 |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| TRIM28 | tripartite motif containing 28 |
| TST | thiosulfate sulfurtransferase (rhodanese) |
| TTPAL | tocopherol (alpha) transfer protein-like |
| UBE2M | ubiquitin-conjugating enzyme E2M |
| VKORC1 | vitamin K epoxide reductase complex, subunit 1 |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) |
| VPS52 | vacuolar protein sorting 52 homolog (S. cerevisiae) |
| WDR6 | WD repeat domain 6 |
| ZBTB48 | zinc finger and BTB domain containing 48 |