| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the dirithromycin-7446 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAMTS13 | ADAM metallopeptidase with thrombospondin type 1 motif, 13 |
| ADAP2 | ArfGAP with dual PH domains 2 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 |
| AIF1 | allograft inflammatory factor 1 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| APOM | apolipoprotein M |
| AQP3 | aquaporin 3 (Gill blood group) |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
| BMP6 | bone morphogenetic protein 6 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CAPN5 | calpain 5 |
| CD53 | CD53 molecule |
| CELA3A | chymotrypsin-like elastase family, member 3A |
| CLTC | clathrin, heavy chain (Hc) |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DCN | decorin |
| EHBP1L1 | EH domain binding protein 1-like 1 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| FAM186A | family with sequence similarity 186, member A |
| FAM212B | family with sequence similarity 212, member B |
| FAM65A | family with sequence similarity 65, member A |
| FOXN3 | forkhead box N3 |
| FUS | FUS RNA binding protein |
| GGT1 | gamma-glutamyltransferase 1 |
| GHRH | growth hormone releasing hormone |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GNPTAB | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GRTP1 | growth hormone regulated TBC protein 1 |
| GVINP1 | GTPase, very large interferon inducible pseudogene 1 |
| HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
| HEMK1 | HemK methyltransferase family member 1 |
| HIST1H2BB | histone cluster 1, H2bb |
| HIST1H4D | histone cluster 1, H4d |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| JMJD4 | jumonji domain containing 4 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KIF25 | kinesin family member 25 |
| LPAR1 | lysophosphatidic acid receptor 1 |
| LPIN1 | lipin 1 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MALL | mal, T-cell differentiation protein-like |
| MAP4 | microtubule-associated protein 4 |
| MAPK8 | mitogen-activated protein kinase 8 |
| MCF2L | MCF.2 cell line derived transforming sequence-like |
| MFAP3L | microfibrillar-associated protein 3-like |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming |
| NF1 | neurofibromin 1 |
| NF2 | neurofibromin 2 (merlin) |
| NKX2-5 | NK2 homeobox 5 |
| NOS1 | nitric oxide synthase 1 (neuronal) |
| NOVA2 | neuro-oncological ventral antigen 2 |
| NRSN2 | neurensin 2 |
| OPRK1 | opioid receptor, kappa 1 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PALM | paralemmin |
| PARD6B | par-6 family cell polarity regulator beta |
| PDCD6 | programmed cell death 6 |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PPP1R14D | protein phosphatase 1, regulatory (inhibitor) subunit 14D |
| PRKCB | protein kinase C, beta |
| PSG11 | pregnancy specific beta-1-glycoprotein 11 |
| RABGAP1L | RAB GTPase activating protein 1-like |
| RECQL5 | RecQ protein-like 5 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RNF122 | ring finger protein 122 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F |
| SFT2D2 | SFT2 domain containing 2 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| SRCAP | Snf2-related CREBBP activator protein |
| STAB1 | stabilin 1 |
| STMN4 | stathmin-like 4 |
| SUGP1 | SURP and G patch domain containing 1 |
| SYNGR1 | synaptogyrin 1 |
| TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) |
| TMC6 | transmembrane channel-like 6 |
| TMEM19 | transmembrane protein 19 |
| TONSL | tonsoku-like, DNA repair protein |
| TREX1 | three prime repair exonuclease 1 |
| TRIM21 | tripartite motif containing 21 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| VSNL1 | visinin-like 1 |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZC3H13 | zinc finger CCCH-type containing 13 |
| Symbol | Name |
|---|---|
| AARSD1 | alanyl-tRNA synthetase domain containing 1 |
| ADCY6 | adenylate cyclase 6 |
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| ADGRG6 | adhesion G protein-coupled receptor G6 |
| AEN | apoptosis enhancing nuclease |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| AXIN1 | axin 1 |
| BCL2L2 | BCL2-like 2 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CBX8 | chromobox homolog 8 |
| CCNT1 | cyclin T1 |
| CDC37L1 | cell division cycle 37-like 1 |
| CERK | ceramide kinase |
| CISH | cytokine inducible SH2-containing protein |
| CLASP1 | cytoplasmic linker associated protein 1 |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CTSK | cathepsin K |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 |
| DUSP5 | dual specificity phosphatase 5 |
| EGR3 | early growth response 3 |
| EPHA2 | EPH receptor A2 |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GCC1 | GRIP and coiled-coil domain containing 1 |
| GPR27 | G protein-coupled receptor 27 |
| GPR87 | G protein-coupled receptor 87 |
| GSTT1 | glutathione S-transferase theta 1 |
| H2AFY2 | H2A histone family, member Y2 |
| HIST1H2AG | histone cluster 1, H2ag |
| IRF9 | interferon regulatory factor 9 |
| IRX4 | iroquois homeobox 4 |
| JRKL | JRK-like |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KLF11 | Kruppel-like factor 11 |
| LAMA3 | laminin, alpha 3 |
| LINS | lines homolog (Drosophila) |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LRRC20 | leucine rich repeat containing 20 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MANBA | mannosidase, beta A, lysosomal |
| MED15 | mediator complex subunit 15 |
| METTL16 | methyltransferase like 16 |
| MFSD10 | major facilitator superfamily domain containing 10 |
| MSANTD2 | Myb/SANT-like DNA-binding domain containing 2 |
| MTCL1 | microtubule crosslinking factor 1 |
| NBEAL2 | neurobeachin-like 2 |
| NISCH | nischarin |
| NMRK1 | nicotinamide riboside kinase 1 |
| NPY1R | neuropeptide Y receptor Y1 |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 |
| PER3 | period circadian clock 3 |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PRR3 | proline rich 3 |
| PTCD2 | pentatricopeptide repeat domain 2 |
| PTK6 | protein tyrosine kinase 6 |
| PTOV1 | prostate tumor overexpressed 1 |
| RANGRF | RAN guanine nucleotide release factor |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RBBP5 | retinoblastoma binding protein 5 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| SF3A2 | splicing factor 3a, subunit 2, 66kDa |
| SFXN3 | sideroflexin 3 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SOX3 | SRY (sex determining region Y)-box 3 |
| SPIDR | scaffolding protein involved in DNA repair |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STK25 | serine/threonine kinase 25 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) |
| TESK2 | testis-specific kinase 2 |
| TMEM39B | transmembrane protein 39B |
| TNNT1 | troponin T type 1 (skeletal, slow) |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TPST1 | tyrosylprotein sulfotransferase 1 |
| UBXN6 | UBX domain protein 6 |
| ULBP2 | UL16 binding protein 2 |
| VGF | VGF nerve growth factor inducible |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| WDR4 | WD repeat domain 4 |
| ZBTB3 | zinc finger and BTB domain containing 3 |
| ZDHHC18 | zinc finger, DHHC-type containing 18 |
| ZNF212 | zinc finger protein 212 |
| ZNF226 | zinc finger protein 226 |
| ZNF250 | zinc finger protein 250 |
| ZNF286A | zinc finger protein 286A |
| ZNF322P1 | zinc finger protein 322 pseudogene 1 |
| ZNF394 | zinc finger protein 394 |
| ZNF668 | zinc finger protein 668 |
| ZXDC | ZXD family zinc finger C |
