distended pericardium Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description an expansion in the volume of the sac-like structure contained by the outer parietal layer of the pericardium (Mammalian Phenotype Ontology, MP_0000292)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0000292
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Genes

52 gene mutations causing the distended pericardium phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADAM10 ADAM metallopeptidase domain 10
ANKRD17 ankyrin repeat domain 17
APH1A APH1A gamma secretase subunit
CCDC160 coiled-coil domain containing 160
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDH5 cadherin 5, type 2 (vascular endothelium)
CFLAR CASP8 and FADD-like apoptosis regulator
CTBP2 C-terminal binding protein 2
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DISP1 dispatched homolog 1 (Drosophila)
EFNB2 ephrin-B2
F2 coagulation factor II (thrombin)
F2R coagulation factor II (thrombin) receptor
F3 coagulation factor III (thromboplastin, tissue factor)
FN1 fibronectin 1
FOXO1 forkhead box O1
GTF2I general transcription factor IIi
GTF2IRD1 GTF2I repeat domain containing 1
HAND2 heart and neural crest derivatives expressed 2
IFT88 intraflagellar transport 88
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
JAG1 jagged 1
JARID2 jumonji, AT rich interactive domain 2
KIF3A kinesin family member 3A
KIF3B kinesin family member 3B
LMO2 LIM domain only 2 (rhombotin-like 1)
MAP2K5 mitogen-activated protein kinase kinase 5
MAPK7 mitogen-activated protein kinase 7
MECOM MDS1 and EVI1 complex locus
MIB1 mindbomb E3 ubiquitin protein ligase 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NCSTN nicastrin
NF1 neurofibromin 1
NOTCH1 notch 1
NR6A1 nuclear receptor subfamily 6, group A, member 1
PAXIP1 PAX interacting (with transcription-activation domain) protein 1
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
POFUT1 protein O-fucosyltransferase 1
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PTPRJ protein tyrosine phosphatase, receptor type, J
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SMAD1 SMAD family member 1
SMN1 survival of motor neuron 1, telomeric
SMO smoothened, frizzled class receptor
SOS1 son of sevenless homolog 1 (Drosophila)
T T, brachyury homolog (mouse)
TAL1 T-cell acute lymphocytic leukemia 1
TBX4 T-box 4
TMOD1 tropomodulin 1
UBP1 upstream binding protein 1 (LBP-1a)
WNK1 WNK lysine deficient protein kinase 1