disulfiram-1369 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the disulfiram-1369 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ALAS1 5'-aminolevulinate synthase 1
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit
ARL4C ADP-ribosylation factor-like 4C
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
ATG13 autophagy related 13
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1
BAG3 BCL2-associated athanogene 3
BMPR1A bone morphogenetic protein receptor, type IA
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
CAPN10 calpain 10
CCNG2 cyclin G2
CCPG1 cell cycle progression 1
CD164 CD164 molecule, sialomucin
CD59 CD59 molecule, complement regulatory protein
CDC37 cell division cycle 37
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CSNK1D casein kinase 1, delta
DDAH2 dimethylarginine dimethylaminohydrolase 2
DERL2 derlin 2
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DUS2 dihydrouridine synthase 2
DUSP13 dual specificity phosphatase 13
ELMO2 engulfment and cell motility 2
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FKBP4 FK506 binding protein 4, 59kDa
FTH1 ferritin, heavy polypeptide 1
FTH1P5 ferritin, heavy polypeptide 1 pseudogene 5
GAB2 GRB2-associated binding protein 2
GADD45B growth arrest and DNA-damage-inducible, beta
GCLM glutamate-cysteine ligase, modifier subunit
GNAS GNAS complex locus
GPR183 G protein-coupled receptor 183
H2BFS H2B histone family, member S (pseudogene)
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA1A heat shock 70kDa protein 1A
HSPA4L heat shock 70kDa protein 4-like
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPB1 heat shock 27kDa protein 1
HSPH1 heat shock 105kDa/110kDa protein 1
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IER5 immediate early response 5
IGFBP7 insulin-like growth factor binding protein 7
IRF2 interferon regulatory factor 2
KIAA1109 KIAA1109
KRIT1 KRIT1, ankyrin repeat containing
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1M metallothionein 1M
MT1X metallothionein 1X
MT2A metallothionein 2A
MT3 metallothionein 3
MXD4 MAX dimerization protein 4
NFX1 nuclear transcription factor, X-box binding 1
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
NQO1 NAD(P)H dehydrogenase, quinone 1
OSTM1 osteopetrosis associated transmembrane protein 1
PLAA phospholipase A2-activating protein
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PTX3 pentraxin 3, long
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RECQL RecQ helicase-like
RECQL5 RecQ protein-like 5
RGS2 regulator of G-protein signaling 2
RIMS3 regulating synaptic membrane exocytosis 3
RPL37A ribosomal protein L37a
S100A10 S100 calcium binding protein A10
SAT1 spermidine/spermine N1-acetyltransferase 1
SCYL3 SCY1-like 3 (S. cerevisiae)
SEC24D SEC24 family member D
SGK1 serum/glucocorticoid regulated kinase 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SOAT1 sterol O-acyltransferase 1
SPATS2L spermatogenesis associated, serine-rich 2-like
SQSTM1 sequestosome 1
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
STK19 serine/threonine kinase 19
STK3 serine/threonine kinase 3
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TIA1 TIA1 cytotoxic granule-associated RNA binding protein
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TPD52 tumor protein D52
TRABD TraB domain containing
TRIB1 tribbles pseudokinase 1
TSPAN31 tetraspanin 31
TSPYL2 TSPY-like 2
UHRF1BP1L UHRF1 binding protein 1-like
USF2 upstream transcription factor 2, c-fos interacting
WSB1 WD repeat and SOCS box containing 1
ZC3H7A zinc finger CCCH-type containing 7A

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ACVR2A activin A receptor, type IIA
ACVR2B activin A receptor, type IIB
ADGRA3 adhesion G protein-coupled receptor A3
ADRM1 adhesion regulating molecule 1
C12ORF49 chromosome 12 open reading frame 49
C8ORF60 chromosome 8 open reading frame 60
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CLDN11 claudin 11
CLTCL1 clathrin, heavy chain-like 1
COQ4 coenzyme Q4
CPA4 carboxypeptidase A4
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DEAF1 DEAF1 transcription factor
DEXI Dexi homolog (mouse)
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DLEU1 deleted in lymphocytic leukemia 1 (non-protein coding)
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
E4F1 E4F transcription factor 1
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ELANE elastase, neutrophil expressed
FAM172A family with sequence similarity 172, member A
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GATAD2A GATA zinc finger domain containing 2A
GLB1L2 galactosidase, beta 1-like 2
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPD1L glycerol-3-phosphate dehydrogenase 1-like
GPR27 G protein-coupled receptor 27
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa
GTPBP6 GTP binding protein 6 (putative)
IFITM3 interferon induced transmembrane protein 3
IL2RB interleukin 2 receptor, beta
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
INO80D INO80 complex subunit D
KIAA0894 KIAA0894 protein
KIAA0930 KIAA0930
KIF5A kinesin family member 5A
KIFC1 kinesin family member C1
LAS1L LAS1-like (S. cerevisiae)
LPCAT1 lysophosphatidylcholine acyltransferase 1
LRPAP1 low density lipoprotein receptor-related protein associated protein 1
LZTR1 leucine-zipper-like transcription regulator 1
MBOAT2 membrane bound O-acyltransferase domain containing 2
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTERF4 mitochondrial transcription termination factor 4
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
MXRA8 matrix-remodelling associated 8
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NAT10 N-acetyltransferase 10 (GCN5-related)
NCKAP1L NCK-associated protein 1-like
NECAB3 N-terminal EF-hand calcium binding protein 3
NOL6 nucleolar protein 6 (RNA-associated)
NOTCH1 notch 1
NTHL1 nth endonuclease III-like 1 (E. coli)
NUBP2 nucleotide binding protein 2
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9
PAGR1 PAXIP1 associated glutamate-rich protein 1
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae)
PCDHGB5 protocadherin gamma subfamily B, 5
PDLIM2 PDZ and LIM domain 2 (mystique)
PES1 pescadillo ribosomal biogenesis factor 1
PEX26 peroxisomal biogenesis factor 26
PFAS phosphoribosylformylglycinamidine synthase
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PISD phosphatidylserine decarboxylase
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
PPAT phosphoribosyl pyrophosphate amidotransferase
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PRPF19 pre-mRNA processing factor 19
PRR14L proline rich 14-like
PRTN3 proteinase 3
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
RBMS3 RNA binding motif, single stranded interacting protein 3
RCL1 RNA terminal phosphate cyclase-like 1
RFTN1 raftlin, lipid raft linker 1
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SCAMP5 secretory carrier membrane protein 5
SCN10A sodium channel, voltage gated, type X alpha subunit
SIRT6 sirtuin 6
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
STAC SH3 and cysteine rich domain
STC2 stanniocalcin 2
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TDRD7 tudor domain containing 7
TERT telomerase reverse transcriptase
TEX40 testis expressed 40
TIAM2 T-cell lymphoma invasion and metastasis 2
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
WDR19 WD repeat domain 19
XDH xanthine dehydrogenase
ZC3H3 zinc finger CCCH-type containing 3
ZIM2 zinc finger, imprinted 2
ZNF529 zinc finger protein 529
ZSCAN26 zinc finger and SCAN domain containing 26