disulfiram-2215 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

196 genes differentially expressed following the disulfiram-2215 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADCY7 adenylate cyclase 7
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AGFG1 ArfGAP with FG repeats 1
AK2 adenylate kinase 2
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ALOXE3 arachidonate lipoxygenase 3
ATF3 activating transcription factor 3
ATF7IP activating transcription factor 7 interacting protein
C17ORF59 chromosome 17 open reading frame 59
CFLAR CASP8 and FADD-like apoptosis regulator
CGA glycoprotein hormones, alpha polypeptide
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLU clusterin
COL2A1 collagen, type II, alpha 1
CRHR2 corticotropin releasing hormone receptor 2
CRYAB crystallin, alpha B
CSRP2 cysteine and glycine-rich protein 2
CTGF connective tissue growth factor
DDIT3 DNA-damage-inducible transcript 3
DGCR2 DiGeorge syndrome critical region gene 2
DGCR8 DGCR8 microprocessor complex subunit
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DUSP1 dual specificity phosphatase 1
EGR1 early growth response 1
EMCN endomucin
ERCC4 excision repair cross-complementation group 4
FAM149A family with sequence similarity 149, member A
FBXO38 F-box protein 38
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXG1 forkhead box G1
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2
GEM GTP binding protein overexpressed in skeletal muscle
GINS4 GINS complex subunit 4 (Sld5 homolog)
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
HDAC7 histone deacetylase 7
HMOX1 heme oxygenase 1
HSPA4L heat shock 70kDa protein 4-like
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
INHBE inhibin, beta E
IRS2 insulin receptor substrate 2
JUN jun proto-oncogene
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KLF12 Kruppel-like factor 12
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAOB monoamine oxidase B
MED18 mediator complex subunit 18
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MKL1 megakaryoblastic leukemia (translocation) 1
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MT2A metallothionein 2A
MTCP1 mature T-cell proliferation 1
NPC1 Niemann-Pick disease, type C1
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A3 nuclear receptor subfamily 4, group A, member 3
NR6A1 nuclear receptor subfamily 6, group A, member 1
PDZD2 PDZ domain containing 2
PLIN2 perilipin 2
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
RABGAP1 RAB GTPase activating protein 1
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
REC8 REC8 meiotic recombination protein
RGS2 regulator of G-protein signaling 2
RND1 Rho family GTPase 1
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNFT1 ring finger protein, transmembrane 1
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SFTPC surfactant protein C
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SOCS2 suppressor of cytokine signaling 2
SPRY4 sprouty homolog 4 (Drosophila)
TGFB2 transforming growth factor, beta 2
THRB thyroid hormone receptor, beta
TPK1 thiamin pyrophosphokinase 1
TRA2B transformer 2 beta homolog (Drosophila)
TRIM16 tripartite motif containing 16
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF518A zinc finger protein 518A
ZNF652 zinc finger protein 652
ZRSR1 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1

decreased expression

Symbol Name
AMPD1 adenosine monophosphate deaminase 1
APOLD1 apolipoprotein L domain containing 1
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
BAHCC1 BAH domain and coiled-coil containing 1
BCAM basal cell adhesion molecule (Lutheran blood group)
BMP15 bone morphogenetic protein 15
CCDC132 coiled-coil domain containing 132
CCNO cyclin O
CCNT1 cyclin T1
CD3D CD3d molecule, delta (CD3-TCR complex)
CD80 CD80 molecule
CDH10 cadherin 10, type 2 (T2-cadherin)
CDK18 cyclin-dependent kinase 18
CEL carboxyl ester lipase
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLGN calmegin
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CNR2 cannabinoid receptor 2 (macrophage)
CORT cortistatin
CRLF1 cytokine receptor-like factor 1
CXADR coxsackie virus and adenovirus receptor
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DIXDC1 DIX domain containing 1
DPY19L1P1 DPY19L1 pseudogene 1
DTX2 deltex 2, E3 ubiquitin ligase
ELSPBP1 epididymal sperm binding protein 1
F3 coagulation factor III (thromboplastin, tissue factor)
FADS2 fatty acid desaturase 2
FAM155A family with sequence similarity 155, member A
FBXL8 F-box and leucine-rich repeat protein 8
FBXO31 F-box protein 31
FLT4 fms-related tyrosine kinase 4
FSTL3 follistatin-like 3 (secreted glycoprotein)
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GLRA1 glycine receptor, alpha 1
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPR157 G protein-coupled receptor 157
GPR27 G protein-coupled receptor 27
GSTCD glutathione S-transferase, C-terminal domain containing
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HIST1H1D histone cluster 1, H1d
HSPA2 heat shock 70kDa protein 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
KLHL28 kelch-like family member 28
KLK5 kallikrein-related peptidase 5
KRT15 keratin 15, type I
LHX1 LIM homeobox 1
LRRC37A2 leucine rich repeat containing 37, member A2
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP1S microtubule-associated protein 1S
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MAP6D1 MAP6 domain containing 1
METTL2B methyltransferase like 2B
MYOZ1 myozenin 1
NEUROD4 neuronal differentiation 4
NRGN neurogranin (protein kinase C substrate, RC3)
NT5E 5'-nucleotidase, ecto (CD73)
ORAI3 ORAI calcium release-activated calcium modulator 3
PADI1 peptidyl arginine deiminase, type I
PCDHB13 protocadherin beta 13
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PLA2G3 phospholipase A2, group III
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PTPRS protein tyrosine phosphatase, receptor type, S
PVRL3 poliovirus receptor-related 3
RAB30 RAB30, member RAS oncogene family
RAD54L RAD54-like (S. cerevisiae)
RCAN3 RCAN family member 3
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RPGRIP1L RPGRIP1-like
SALL2 spalt-like transcription factor 2
SCAMP3 secretory carrier membrane protein 3
SCN1B sodium channel, voltage gated, type I beta subunit
SDC3 syndecan 3
SKI SKI proto-oncogene
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
ST5 suppression of tumorigenicity 5
STAB2 stabilin 2
STIM1 stromal interaction molecule 1
STON1 stonin 1
SYNC syncoilin, intermediate filament protein
TICAM1 toll-like receptor adaptor molecule 1
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast)
TMEM121 transmembrane protein 121
TMLHE trimethyllysine hydroxylase, epsilon
TRABD TraB domain containing
TRPV1 transient receptor potential cation channel, subfamily V, member 1
USB1 U6 snRNA biogenesis 1
WLS wntless Wnt ligand secretion mediator
ZBTB44 zinc finger and BTB domain containing 44