dizocilpine-2232 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the dizocilpine-2232 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A1CF APOBEC1 complementation factor
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4
ACVR1B activin A receptor, type IB
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
APLNR apelin receptor
APLP1 amyloid beta (A4) precursor-like protein 1
ARL4D ADP-ribosylation factor-like 4D
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATF6B activating transcription factor 6 beta
ATF7IP activating transcription factor 7 interacting protein
AVPR1B arginine vasopressin receptor 1B
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BMP8B bone morphogenetic protein 8b
BST2 bone marrow stromal cell antigen 2
CD4 CD4 molecule
CD6 CD6 molecule
CD79A CD79a molecule, immunoglobulin-associated alpha
CLDN17 claudin 17
COL6A1 collagen, type VI, alpha 1
DGCR8 DGCR8 microprocessor complex subunit
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
EDA ectodysplasin A
FBXO21 F-box protein 21
GK3P glycerol kinase 3 pseudogene
GMPR guanosine monophosphate reductase
HBEGF heparin-binding EGF-like growth factor
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HNF1B HNF1 homeobox B
HOXB2 homeobox B2
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IL1B interleukin 1, beta
INE1 inactivation escape 1 (non-protein coding)
IPW imprinted in Prader-Willi syndrome (non-protein coding)
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KIF5A kinesin family member 5A
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KIR3DX1 killer cell immunoglobulin-like receptor, three domains, X1
KMT2A lysine (K)-specific methyltransferase 2A
LINC00652 long intergenic non-protein coding RNA 652
MAN1C1 mannosidase, alpha, class 1C, member 1
MBOAT2 membrane bound O-acyltransferase domain containing 2
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MNMIP1 manchette microtubule inner protein 1
MOB3B MOB kinase activator 3B
MTNR1A melatonin receptor 1A
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MYL10 myosin, light chain 10, regulatory
NCF4 neutrophil cytosolic factor 4, 40kDa
NF2 neurofibromin 2 (merlin)
NPR1 natriuretic peptide receptor 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
NUP188 nucleoporin 188kDa
ONECUT2 one cut homeobox 2
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCBP3 poly(rC) binding protein 3
PCDH11X protocadherin 11 X-linked
PLCD1 phospholipase C, delta 1
PRDM12 PR domain containing 12
PTAFR platelet-activating factor receptor
PTPRJ protein tyrosine phosphatase, receptor type, J
PVR poliovirus receptor
QKI QKI, KH domain containing, RNA binding
RBM5 RNA binding motif protein 5
RND1 Rho family GTPase 1
RORC RAR-related orphan receptor C
RUNX1 runt-related transcription factor 1
S100A6 S100 calcium binding protein A6
S100A8 S100 calcium binding protein A8
SAA3P serum amyloid A3 pseudogene
SARM1 sterile alpha and TIR motif containing 1
SCRN3 secernin 3
SFTPC surfactant protein C
SIDT2 SID1 transmembrane family, member 2
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SMAD5 SMAD family member 5
SORBS1 sorbin and SH3 domain containing 1
SORT1 sortilin 1
SOS2 son of sevenless homolog 2 (Drosophila)
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SRSF7 serine/arginine-rich splicing factor 7
ST20 suppressor of tumorigenicity 20
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SYNDIG1 synapse differentiation inducing 1
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TCP10L t-complex 10-like
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFG TRK-fused gene
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TMEM206 transmembrane protein 206
UBE2I ubiquitin-conjugating enzyme E2I
USP46 ubiquitin specific peptidase 46
VPS9D1 VPS9 domain containing 1
WDR59 WD repeat domain 59
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
ZNF112 zinc finger protein 112
ZSWIM1 zinc finger, SWIM-type containing 1

decreased expression

Symbol Name
ANKRD7 ankyrin repeat domain 7
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
B9D2 B9 protein domain 2
C5AR2 complement component 5a receptor 2
CA11 carbonic anhydrase XI
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CCDC134 coiled-coil domain containing 134
CCDC25 coiled-coil domain containing 25
CDH10 cadherin 10, type 2 (T2-cadherin)
CDK18 cyclin-dependent kinase 18
CDK3 cyclin-dependent kinase 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDON cell adhesion associated, oncogene regulated
CERS4 ceramide synthase 4
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CNKSR2 connector enhancer of kinase suppressor of Ras 2
CSF1R colony stimulating factor 1 receptor
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DOK5 docking protein 5
EMCN endomucin
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM155A family with sequence similarity 155, member A
FBXO31 F-box protein 31
FGF23 fibroblast growth factor 23
FMO4 flavin containing monooxygenase 4
FRK fyn-related Src family tyrosine kinase
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GATA4 GATA binding protein 4
GLRA1 glycine receptor, alpha 1
GPR157 G protein-coupled receptor 157
GPR27 G protein-coupled receptor 27
GPRC5D G protein-coupled receptor, class C, group 5, member D
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H4A histone cluster 1, H4a
IQSEC2 IQ motif and Sec7 domain 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
JMJD4 jumonji domain containing 4
JUNB jun B proto-oncogene
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KLHL25 kelch-like family member 25
LARP6 La ribonucleoprotein domain family, member 6
LRP2 low density lipoprotein receptor-related protein 2
MAGEB2 melanoma antigen family B2
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MVP major vault protein
MYOZ1 myozenin 1
NEUROD4 neuronal differentiation 4
NKX3-2 NK3 homeobox 2
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLD3 phospholipase D family, member 3
PLEKHO2 pleckstrin homology domain containing, family O member 2
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
POLL polymerase (DNA directed), lambda
POLM polymerase (DNA directed), mu
PQLC2 PQ loop repeat containing 2
PRICKLE3 prickle homolog 3 (Drosophila)
PRODH proline dehydrogenase (oxidase) 1
PTDSS2 phosphatidylserine synthase 2
RAD54L2 RAD54-like 2 (S. cerevisiae)
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RCAN3 RCAN family member 3
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RFPL1S RFPL1 antisense RNA 1
RNF122 ring finger protein 122
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
S100A9 S100 calcium binding protein A9
SEC14L5 SEC14-like 5 (S. cerevisiae)
SIK1 salt-inducible kinase 1
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
STAG3 stromal antigen 3
STX2 syntaxin 2
TAGLN transgelin
TLR2 toll-like receptor 2
TNS2 tensin 2
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSPAN2 tetraspanin 2
UNC93B1 unc-93 homolog B1 (C. elegans)
UNKL unkempt family zinc finger-like
UPP1 uridine phosphorylase 1
USB1 U6 snRNA biogenesis 1
USP20 ubiquitin specific peptidase 20
USP27X ubiquitin specific peptidase 27, X-linked
XYLT2 xylosyltransferase II
ZNF250 zinc finger protein 250
ZNF37BP zinc finger protein 37B, pseudogene
ZNF446 zinc finger protein 446
ZNF74 zinc finger protein 74