dizocilpine-5746 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the dizocilpine-5746 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ARNT aryl hydrocarbon receptor nuclear translocator
AURKC aurora kinase C
BMP10 bone morphogenetic protein 10
C14ORF93 chromosome 14 open reading frame 93
C1ORF54 chromosome 1 open reading frame 54
C1ORF95 chromosome 1 open reading frame 95
CA12 carbonic anhydrase XII
CABP2 calcium binding protein 2
CAMK4 calcium/calmodulin-dependent protein kinase IV
CCDC7 coiled-coil domain containing 7
CD34 CD34 molecule
CD80 CD80 molecule
CFAP70 cilia and flagella associated protein 70
CLCA2 chloride channel accessory 2
CLDN9 claudin 9
CREB3L1 cAMP responsive element binding protein 3-like 1
CROCC ciliary rootlet coiled-coil, rootletin
CXCR4 chemokine (C-X-C motif) receptor 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DES desmin
DKFZP434L187 uncharacterized LOC26082
DTNB dystrobrevin, beta
E2F4 E2F transcription factor 4, p107/p130-binding
EDA ectodysplasin A
EDNRB endothelin receptor type B
ELN elastin
ESR1 estrogen receptor 1
FABP7 fatty acid binding protein 7, brain
FBXO21 F-box protein 21
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FRMD1 FERM domain containing 1
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GABRQ gamma-aminobutyric acid (GABA) A receptor, theta
GDF5 growth differentiation factor 5
GHRHR growth hormone releasing hormone receptor
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GPR85 G protein-coupled receptor 85
HAL histidine ammonia-lyase
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HSPB6 heat shock protein, alpha-crystallin-related, B6
IFNA4 interferon, alpha 4
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KLK7 kallikrein-related peptidase 7
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LIMK2 LIM domain kinase 2
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
MLXIP MLX interacting protein
MR1 major histocompatibility complex, class I-related
MTMR8 myotubularin related protein 8
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
NEBL nebulette
NEFM neurofilament, medium polypeptide
NF1 neurofibromin 1
NR1H4 nuclear receptor subfamily 1, group H, member 4
ONECUT2 one cut homeobox 2
OR2F2 olfactory receptor, family 2, subfamily F, member 2
OSBPL10 oxysterol binding protein-like 10
PDE12 phosphodiesterase 12
PELI2 pellino E3 ubiquitin protein ligase family member 2
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PKNOX2 PBX/knotted 1 homeobox 2
PLIN2 perilipin 2
PLXNC1 plexin C1
PODNL1 podocan-like 1
PRB1 proline-rich protein BstNI subfamily 1
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRKG2 protein kinase, cGMP-dependent, type II
PTP4A3 protein tyrosine phosphatase type IVA, member 3
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RFPL3 ret finger protein-like 3
RPP25 ribonuclease P/MRP 25kDa subunit
RUNX1 runt-related transcription factor 1
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SIX3 SIX homeobox 3
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3
SNCG synuclein, gamma (breast cancer-specific protein 1)
SNTG1 syntrophin, gamma 1
SPTAN1 spectrin, alpha, non-erythrocytic 1
SSTR5 somatostatin receptor 5
TAPT1 transmembrane anterior posterior transformation 1
TAS2R1 taste receptor, type 2, member 1
TFEB transcription factor EB
TJP3 tight junction protein 3
TMCC1 transmembrane and coiled-coil domain family 1
TMEM212 transmembrane protein 212
TMEM74B transmembrane protein 74B
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TSPAN2 tetraspanin 2
USP27X ubiquitin specific peptidase 27, X-linked
USP46 ubiquitin specific peptidase 46
XDH xanthine dehydrogenase
ZNF440 zinc finger protein 440
ZNF639 zinc finger protein 639
ZNF702P zinc finger protein 702, pseudogene
ZNF778 zinc finger protein 778

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACTG2 actin, gamma 2, smooth muscle, enteric
ACYP2 acylphosphatase 2, muscle type
ADGRG2 adhesion G protein-coupled receptor G2
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
BBS7 Bardet-Biedl syndrome 7
BMP15 bone morphogenetic protein 15
C22ORF29 chromosome 22 open reading frame 29
CCNA1 cyclin A1
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CEMIP cell migration inducing protein, hyaluronan binding
CENPO centromere protein O
CEP295 centrosomal protein 295kDa
CHRM3 cholinergic receptor, muscarinic 3
CNGB3 cyclic nucleotide gated channel beta 3
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
COG4 component of oligomeric golgi complex 4
COQ6 coenzyme Q6 monooxygenase
CRY2 cryptochrome circadian clock 2
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DMTN dematin actin binding protein
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DTX2 deltex 2, E3 ubiquitin ligase
E2F8 E2F transcription factor 8
EFNB1 ephrin-B1
EPN3 epsin 3
ERAP2 endoplasmic reticulum aminopeptidase 2
ERCC5 excision repair cross-complementation group 5
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM222B family with sequence similarity 222, member B
FRS3 fibroblast growth factor receptor substrate 3
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GDAP1 ganglioside induced differentiation associated protein 1
GLCE glucuronic acid epimerase
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPATCH2L G patch domain containing 2-like
GRAMD1C GRAM domain containing 1C
GRB7 growth factor receptor-bound protein 7
GRWD1 glutamate-rich WD repeat containing 1
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
IFI6 interferon, alpha-inducible protein 6
IL15RA interleukin 15 receptor, alpha
IL17RB interleukin 17 receptor B
IQCG IQ motif containing G
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KDM5C lysine (K)-specific demethylase 5C
KRT15 keratin 15, type I
LIF leukemia inhibitory factor
LIPG lipase, endothelial
LZTR1 leucine-zipper-like transcription regulator 1
MAGEB2 melanoma antigen family B2
MDFI MyoD family inhibitor
MED9 mediator complex subunit 9
MFGE8 milk fat globule-EGF factor 8 protein
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MPG N-methylpurine-DNA glycosylase
MT1M metallothionein 1M
MYLIP myosin regulatory light chain interacting protein
NDP Norrie disease (pseudoglioma)
NPY1R neuropeptide Y receptor Y1
NR3C2 nuclear receptor subfamily 3, group C, member 2
NRTN neurturin
NUP62CL nucleoporin 62kDa C-terminal like
NXPH4 neurexophilin 4
P3H2 prolyl 3-hydroxylase 2
PAIP2B poly(A) binding protein interacting protein 2B
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLD2 phospholipase D2
PLD3 phospholipase D family, member 3
PLEKHO2 pleckstrin homology domain containing, family O member 2
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PRICKLE3 prickle homolog 3 (Drosophila)
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RHOBTB1 Rho-related BTB domain containing 1
RRAGB Ras-related GTP binding B
SCAMP5 secretory carrier membrane protein 5
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SNORA21 small nucleolar RNA, H/ACA box 21
SNTA1 syntrophin, alpha 1
SPRYD7 SPRY domain containing 7
STBD1 starch binding domain 1
SULT4A1 sulfotransferase family 4A, member 1
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TMEM132A transmembrane protein 132A
TRAF2 TNF receptor-associated factor 2
UBTD1 ubiquitin domain containing 1
ZFHX2 zinc finger homeobox 2
ZNF276 zinc finger protein 276
ZNF668 zinc finger protein 668
ZNF862 zinc finger protein 862
ZNHIT2 zinc finger, HIT-type containing 2