dl-alpha tocopherol-6616 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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194 genes differentially expressed following the dl-alpha tocopherol-6616 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAP1 ArfGAP with dual PH domains 1
AKAP5 A kinase (PRKA) anchor protein 5
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ALK anaplastic lymphoma receptor tyrosine kinase
ANGPTL2 angiopoietin-like 2
ANP32A-IT1 ANP32A intronic transcript 1
APOH apolipoprotein H (beta-2-glycoprotein I)
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
BAAT bile acid CoA:amino acid N-acyltransferase
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BTG2 BTG family, member 2
C16ORF58 chromosome 16 open reading frame 58
CALHM2 calcium homeostasis modulator 2
CD22 CD22 molecule
CDC25C cell division cycle 25C
CDC42 cell division cycle 42
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CEL carboxyl ester lipase
CLEC11A C-type lectin domain family 11, member A
COL5A1 collagen, type V, alpha 1
CORO1A coronin, actin binding protein, 1A
CXCL13 chemokine (C-X-C motif) ligand 13
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DLX2 distal-less homeobox 2
DNAAF1 dynein, axonemal, assembly factor 1
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DPF3 D4, zinc and double PHD fingers, family 3
DVL2 dishevelled segment polarity protein 2
EDDM3A epididymal protein 3A
EMX1 empty spiracles homeobox 1
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
EYA2 EYA transcriptional coactivator and phosphatase 2
FGF1 fibroblast growth factor 1 (acidic)
FILIP1L filamin A interacting protein 1-like
FXYD2 FXYD domain containing ion transport regulator 2
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GIMAP5 GTPase, IMAP family member 5
GSTTP1 glutathione S-transferase theta pseudogene 1
GTPBP1 GTP binding protein 1
HCFC1 host cell factor C1
HHAT hedgehog acyltransferase
HIST1H2AB histone cluster 1, H2ab
IDS iduronate 2-sulfatase
IGLV3-19 immunoglobulin lambda variable 3-19
ING4 inhibitor of growth family, member 4
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KDM8 lysine (K)-specific demethylase 8
KLF13 Kruppel-like factor 13
KRT7 keratin 7, type II
LAMP1 lysosomal-associated membrane protein 1
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LIME1 Lck interacting transmembrane adaptor 1
LOX lysyl oxidase
LY6D lymphocyte antigen 6 complex, locus D
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MTMR3 myotubularin related protein 3
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
NPY2R neuropeptide Y receptor Y2
NUDC nudC nuclear distribution protein
PAQR5 progestin and adipoQ receptor family member V
PAX2 paired box 2
PDE11A phosphodiesterase 11A
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PNPLA2 patatin-like phospholipase domain containing 2
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PRPH peripherin
PRUNE2 prune homolog 2 (Drosophila)
RBM48 RNA binding motif protein 48
RGS5 regulator of G-protein signaling 5
RUNX1 runt-related transcription factor 1
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SH3D21 SH3 domain containing 21
SKIL SKI-like proto-oncogene
SMO smoothened, frizzled class receptor
SOS2 son of sevenless homolog 2 (Drosophila)
SOSTDC1 sclerostin domain containing 1
SPRR2B small proline-rich protein 2B
STRA6 stimulated by retinoic acid 6
SVIL supervillin
SYNJ1 synaptojanin 1
TEX15 testis expressed 15
TFF3 trefoil factor 3 (intestinal)
TINAGL1 tubulointerstitial nephritis antigen-like 1
TJP3 tight junction protein 3
TLK1 tousled-like kinase 1
TLR5 toll-like receptor 5
TMEM180 transmembrane protein 180
TNPO2 transportin 2
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae)
XDH xanthine dehydrogenase
ZKSCAN8 zinc finger with KRAB and SCAN domains 8
ZNF3 zinc finger protein 3

decreased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ANXA2P3 annexin A2 pseudogene 3
AOC2 amine oxidase, copper containing 2 (retina-specific)
ATF7IP2 activating transcription factor 7 interacting protein 2
BFSP1 beaded filament structural protein 1, filensin
C11ORF80 chromosome 11 open reading frame 80
C16ORF62 chromosome 16 open reading frame 62
C17ORF70 chromosome 17 open reading frame 70
C22ORF29 chromosome 22 open reading frame 29
C5ORF45 chromosome 5 open reading frame 45
CA11 carbonic anhydrase XI
CAPN15 calpain 15
CCNO cyclin O
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CDT1 chromatin licensing and DNA replication factor 1
CEP131 centrosomal protein 131kDa
CIDEB cell death-inducing DFFA-like effector b
CLDN15 claudin 15
CNGB3 cyclic nucleotide gated channel beta 3
CORT cortistatin
DBF4B DBF4 zinc finger B
DDN dendrin
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DLK2 delta-like 2 homolog (Drosophila)
ELP6 elongator acetyltransferase complex subunit 6
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ETNK2 ethanolamine kinase 2
FA2H fatty acid 2-hydroxylase
FANCC Fanconi anemia, complementation group C
FBXL7 F-box and leucine-rich repeat protein 7
FBXO2 F-box protein 2
FLT4 fms-related tyrosine kinase 4
FOXC1 forkhead box C1
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GEMIN8 gem (nuclear organelle) associated protein 8
GLS2 glutaminase 2 (liver, mitochondrial)
GUSBP3 glucuronidase, beta pseudogene 3
HDAC11 histone deacetylase 11
HIST1H2AK histone cluster 1, H2ak
HIST1H2AM histone cluster 1, H2am
HIST1H2BJ histone cluster 1, H2bj
HYAL3 hyaluronoglucosaminidase 3
IGFLR1 IGF-like family receptor 1
IQSEC2 IQ motif and Sec7 domain 2
ITFG2 integrin alpha FG-GAP repeat containing 2
ITPKC inositol-trisphosphate 3-kinase C
KDM7A lysine (K)-specific demethylase 7A
KIAA1107 KIAA1107
KLF2 Kruppel-like factor 2
KLHL26 kelch-like family member 26
LIPG lipase, endothelial
LOC100127972 uncharacterized LOC100127972
LRRK1 leucine-rich repeat kinase 1
LYPD3 LY6/PLAUR domain containing 3
NABP1 nucleic acid binding protein 1
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NT5DC3 5'-nucleotidase domain containing 3
PARP3 poly (ADP-ribose) polymerase family, member 3
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDE8B phosphodiesterase 8B
PLAC8 placenta-specific 8
PLD3 phospholipase D family, member 3
PRF1 perforin 1 (pore forming protein)
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
RAB3B RAB3B, member RAS oncogene family
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPL23AP32 ribosomal protein L23a pseudogene 32
SCAMP5 secretory carrier membrane protein 5
SCD5 stearoyl-CoA desaturase 5
SKA1 spindle and kinetochore associated complex subunit 1
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SND1-IT1 SND1 intronic transcript 1
SPRYD7 SPRY domain containing 7
SREK1IP1 SREK1-interacting protein 1
ST5 suppression of tumorigenicity 5
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TMEM120B transmembrane protein 120B
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRIM25 tripartite motif containing 25
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TSKU tsukushi, small leucine rich proteoglycan
TUBA4B tubulin, alpha 4b
USB1 U6 snRNA biogenesis 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WDR18 WD repeat domain 18
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZFHX3 zinc finger homeobox 3
ZNF273 zinc finger protein 273
ZNF324 zinc finger protein 324
ZNF358 zinc finger protein 358
ZNF442 zinc finger protein 442
ZNF549 zinc finger protein 549
ZNF862 zinc finger protein 862