Large protein complex composed of the RNA polymerase core complex and a variety of other proteins including transcription factor complexes TFIIA, D, E, F, and H which are required for promoter recognition, and the Mediator subcomplex. Catalyzes the synthesis of eukaryotic pre-mRNA. (Gene Ontology, GO_0016591)
10 proteins localized to the dna-directed rna polymerase ii, holoenzyme cellular component from the curated GO Cellular Component Annotations 2015 dataset.