docosahexaenoic acid ethyl ester-664 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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195 genes differentially expressed following the docosahexaenoic acid ethyl ester-664 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ABHD6 abhydrolase domain containing 6
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
AMIGO2 adhesion molecule with Ig-like domain 2
ANGPTL4 angiopoietin-like 4
ANKRD27 ankyrin repeat domain 27 (VPS9 domain)
AP1AR adaptor-related protein complex 1 associated regulatory protein
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
AQP6 aquaporin 6, kidney specific
ATG13 autophagy related 13
BICD1 bicaudal D homolog 1 (Drosophila)
BICD2 bicaudal D homolog 2 (Drosophila)
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
BTBD2 BTB (POZ) domain containing 2
C19ORF66 chromosome 19 open reading frame 66
CCDC85B coiled-coil domain containing 85B
CD8A CD8a molecule
CDK17 cyclin-dependent kinase 17
CFD complement factor D (adipsin)
CROT carnitine O-octanoyltransferase
CST8 cystatin 8 (cystatin-related epididymal specific)
DDX23 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DPP4 dipeptidyl-peptidase 4
DUS2 dihydrouridine synthase 2
EFNB3 ephrin-B3
EIF5B eukaryotic translation initiation factor 5B
FABP4 fatty acid binding protein 4, adipocyte
FAM169A family with sequence similarity 169, member A
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GALR3 galanin receptor 3
GCLM glutamate-cysteine ligase, modifier subunit
GIMAP5 GTPase, IMAP family member 5
GNA12 guanine nucleotide binding protein (G protein) alpha 12
HINFP histone H4 transcription factor
HMOX1 heme oxygenase 1
HOXC4 homeobox C4
HSPA1A heat shock 70kDa protein 1A
HSPH1 heat shock 105kDa/110kDa protein 1
KDM4B lysine (K)-specific demethylase 4B
KIAA0141 KIAA0141
KIFAP3 kinesin-associated protein 3
KLF6 Kruppel-like factor 6
LENEP lens epithelial protein
LRP12 low density lipoprotein receptor-related protein 12
LRRC1 leucine rich repeat containing 1
LUZP1 leucine zipper protein 1
MAP4 microtubule-associated protein 4
MAPK3 mitogen-activated protein kinase 3
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NIPAL2 NIPA-like domain containing 2
NRP1 neuropilin 1
PCGF1 polycomb group ring finger 1
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PLIN2 perilipin 2
PNPLA4 patatin-like phospholipase domain containing 4
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme
PPP1R3D protein phosphatase 1, regulatory subunit 3D
RAB2A RAB2A, member RAS oncogene family
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
RNF216 ring finger protein 216
RNMT RNA (guanine-7-) methyltransferase
SAT1 spermidine/spermine N1-acetyltransferase 1
SCAMP1 secretory carrier membrane protein 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SIK2 salt-inducible kinase 2
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMO smoothened, frizzled class receptor
SMYD5 SMYD family member 5
SOCS5 suppressor of cytokine signaling 5
SORBS3 sorbin and SH3 domain containing 3
SOX21 SRY (sex determining region Y)-box 21
SPDEF SAM pointed domain containing ETS transcription factor
SPEG SPEG complex locus
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
STRN3 striatin, calmodulin binding protein 3
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)
TFF3 trefoil factor 3 (intestinal)
TMC6 transmembrane channel-like 6
TPMT thiopurine S-methyltransferase
TPST2 tyrosylprotein sulfotransferase 2
TRIM16 tripartite motif containing 16
UBE2O ubiquitin-conjugating enzyme E2O
UGDH UDP-glucose 6-dehydrogenase
USF2 upstream transcription factor 2, c-fos interacting
VEGFA vascular endothelial growth factor A
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
ABHD11 abhydrolase domain containing 11
ADAP2 ArfGAP with dual PH domains 2
AGRP agouti related neuropeptide
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
ANXA2P1 annexin A2 pseudogene 1
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
APOB apolipoprotein B
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ARSB arylsulfatase B
AVPR1B arginine vasopressin receptor 1B
BCL2L14 BCL2-like 14 (apoptosis facilitator)
C9ORF114 chromosome 9 open reading frame 114
CA14 carbonic anhydrase XIV
CAV3 caveolin 3
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
CD79A CD79a molecule, immunoglobulin-associated alpha
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
DHRS11 dehydrogenase/reductase (SDR family) member 11
DOCK1 dedicator of cytokinesis 1
DRP2 dystrophin related protein 2
DUSP8 dual specificity phosphatase 8
ECHDC2 enoyl CoA hydratase domain containing 2
EPX eosinophil peroxidase
FAM155B family with sequence similarity 155, member B
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GAS8-AS1 GAS8 antisense RNA 1
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GP6 glycoprotein VI (platelet)
GPR3 G protein-coupled receptor 3
GPRC5D G protein-coupled receptor, class C, group 5, member D
GPX2 glutathione peroxidase 2
GRAMD4 GRAM domain containing 4
HIST3H2A histone cluster 3, H2a
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3
HSPB6 heat shock protein, alpha-crystallin-related, B6
IFNA4 interferon, alpha 4
IVL involucrin
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14
KIAA1549L KIAA1549-like
KIF5A kinesin family member 5A
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KLHL1 kelch-like family member 1
KRI1 KRI1 homolog (S. cerevisiae)
KRT1 keratin 1, type II
LIF leukemia inhibitory factor
LIN7B lin-7 homolog B (C. elegans)
LINC01558 long intergenic non-protein coding RNA 1558
LY6G6D lymphocyte antigen 6 complex, locus G6D
MFGE8 milk fat globule-EGF factor 8 protein
MFSD10 major facilitator superfamily domain containing 10
MT4 metallothionein 4
MYLIP myosin regulatory light chain interacting protein
NAAA N-acylethanolamine acid amidase
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
OGFRL1 opioid growth factor receptor-like 1
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PCDHGB5 protocadherin gamma subfamily B, 5
PCOLCE procollagen C-endopeptidase enhancer
PDE8B phosphodiesterase 8B
PF4 platelet factor 4
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PKD2L1 polycystic kidney disease 2-like 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein
PMEL premelanosome protein
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
PON3 paraoxonase 3
RCVRN recoverin
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RHOBTB1 Rho-related BTB domain containing 1
S100A12 S100 calcium binding protein A12
S1PR4 sphingosine-1-phosphate receptor 4
SASH3 SAM and SH3 domain containing 3
SHPK sedoheptulokinase
SIPA1 signal-induced proliferation-associated 1
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
TMEM204 transmembrane protein 204
TMEM209 transmembrane protein 209
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TOM1 target of myb1 (chicken)
TSHB thyroid stimulating hormone, beta
TTR transthyretin
UBQLN4 ubiquilin 4
VGF VGF nerve growth factor inducible
VSIG10 V-set and immunoglobulin domain containing 10
ZNF532 zinc finger protein 532
ZNF652 zinc finger protein 652