domperidone-1301 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the domperidone-1301 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACYP1 acylphosphatase 1, erythrocyte (common) type
AEN apoptosis enhancing nuclease
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ATP11A ATPase, class VI, type 11A
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
BEX1 brain expressed, X-linked 1
C17ORF53 chromosome 17 open reading frame 53
CAPN10 calpain 10
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCPG1 cell cycle progression 1
CDK6 cyclin-dependent kinase 6
CEP72 centrosomal protein 72kDa
CHEK1 checkpoint kinase 1
CLGN calmegin
COL4A2 collagen, type IV, alpha 2
CREM cAMP responsive element modulator
CSE1L CSE1 chromosome segregation 1-like (yeast)
CTH cystathionine gamma-lyase
CYB5B cytochrome b5 type B (outer mitochondrial membrane)
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DOCK5 dedicator of cytokinesis 5
DUSP4 dual specificity phosphatase 4
DZIP3 DAZ interacting zinc finger protein 3
EML3 echinoderm microtubule associated protein like 3
FAM204A family with sequence similarity 204, member A
FBXO11 F-box protein 11
FBXW11 F-box and WD repeat domain containing 11
FCF1 FCF1 rRNA-processing protein
FERMT1 fermitin family member 1
FPGT fucose-1-phosphate guanylyltransferase
GPALPP1 GPALPP motifs containing 1
GPR65 G protein-coupled receptor 65
GTF2I general transcription factor IIi
HIST1H2BI histone cluster 1, H2bi
HRSP12 heat-responsive protein 12
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
IDS iduronate 2-sulfatase
IL1R1 interleukin 1 receptor, type I
IL6ST interleukin 6 signal transducer
INF2 inverted formin, FH2 and WH2 domain containing
KAZN kazrin, periplakin interacting protein
KYNU kynureninase
LARP4 La ribonucleoprotein domain family, member 4
LINC00094 long intergenic non-protein coding RNA 94
LINS lines homolog (Drosophila)
MAP4 microtubule-associated protein 4
MAPK8 mitogen-activated protein kinase 8
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED27 mediator complex subunit 27
MT1G metallothionein 1G
MTAP methylthioadenosine phosphorylase
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa
NEK1 NIMA-related kinase 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
NUP160 nucleoporin 160kDa
NXT2 nuclear transport factor 2-like export factor 2
PCGF2 polycomb group ring finger 2
PER3 period circadian clock 3
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PPID peptidylprolyl isomerase D
PRIM2 primase, DNA, polypeptide 2 (58kDa)
PRKDC protein kinase, DNA-activated, catalytic polypeptide
RECQL RecQ helicase-like
RET ret proto-oncogene
RNF126P1 ring finger protein 126 pseudogene 1
SAP30 Sin3A-associated protein, 30kDa
SCAMP1 secretory carrier membrane protein 1
SCARB1 scavenger receptor class B, member 1
SIDT1 SID1 transmembrane family, member 1
SIRT5 sirtuin 5
SNRPN small nuclear ribonucleoprotein polypeptide N
SPAST spastin
SPCS3 signal peptidase complex subunit 3 homolog (S. cerevisiae)
SPN sialophorin
SRSF11 serine/arginine-rich splicing factor 11
SS18 synovial sarcoma translocation, chromosome 18
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
STX16 syntaxin 16
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
THBS1 thrombospondin 1
TMEM209 transmembrane protein 209
TMEM63A transmembrane protein 63A
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast)
TRAIP TRAF interacting protein
TRAM2 translocation associated membrane protein 2
TSTA3 tissue specific transplantation antigen P35B
TWF1 twinfilin actin binding protein 1
UNC45A unc-45 homolog A (C. elegans)
VDAC3 voltage-dependent anion channel 3
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)
YY2 YY2 transcription factor
ZBTB38 zinc finger and BTB domain containing 38
ZDHHC18 zinc finger, DHHC-type containing 18
ZEB1 zinc finger E-box binding homeobox 1
ZNF174 zinc finger protein 174

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AIM2 absent in melanoma 2
AOAH acyloxyacyl hydrolase (neutrophil)
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ASCC2 activating signal cointegrator 1 complex subunit 2
ASGR2 asialoglycoprotein receptor 2
BAHD1 bromo adjacent homology domain containing 1
BBC3 BCL2 binding component 3
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
BTBD18 BTB (POZ) domain containing 18
C11ORF21 chromosome 11 open reading frame 21
C6ORF47 chromosome 6 open reading frame 47
CAPN15 calpain 15
CCRL2 chemokine (C-C motif) receptor-like 2
CD151 CD151 molecule (Raph blood group)
CD3D CD3d molecule, delta (CD3-TCR complex)
CEP170B centrosomal protein 170B
CLDN15 claudin 15
COL15A1 collagen, type XV, alpha 1
CPPED1 calcineurin-like phosphoesterase domain containing 1
CPTP ceramide-1-phosphate transfer protein
CTDNEP1 CTD nuclear envelope phosphatase 1
DEAF1 DEAF1 transcription factor
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DPF2 D4, zinc and double PHD fingers family 2
DUSP8 dual specificity phosphatase 8
EDC4 enhancer of mRNA decapping 4
ERCC2 excision repair cross-complementation group 2
ETV6 ets variant 6
FAM53B family with sequence similarity 53, member B
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FCHO1 FCH domain only 1
FICD FIC domain containing
FKBP9 FK506 binding protein 9, 63 kDa
FMNL1 formin-like 1
GPSM3 G-protein signaling modulator 3
HELZ helicase with zinc finger
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
JUP junction plakoglobin
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KDM5C lysine (K)-specific demethylase 5C
LGALS9 lectin, galactoside-binding, soluble, 9
LMNB2 lamin B2
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
MAN2B1 mannosidase, alpha, class 2B, member 1
MAPKBP1 mitogen-activated protein kinase binding protein 1
MCOLN1 mucolipin 1
METTL8 methyltransferase like 8
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NABP2 nucleic acid binding protein 2
NCF1C neutrophil cytosolic factor 1C pseudogene
NPDC1 neural proliferation, differentiation and control, 1
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae)
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
PDLIM2 PDZ and LIM domain 2 (mystique)
PFDN1 prefoldin subunit 1
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PKN1 protein kinase N1
PLA2G12A phospholipase A2, group XIIA
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
RAD54L2 RAD54-like 2 (S. cerevisiae)
RBM41 RNA binding motif protein 41
RBM42 RNA binding motif protein 42
RNF2 ring finger protein 2
RNF31 ring finger protein 31
S1PR4 sphingosine-1-phosphate receptor 4
SCPEP1 serine carboxypeptidase 1
SETD8 SET domain containing (lysine methyltransferase) 8
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SLPI secretory leukocyte peptidase inhibitor
SND1-IT1 SND1 intronic transcript 1
SPATS2 spermatogenesis associated, serine-rich 2
SREK1IP1 SREK1-interacting protein 1
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STIM1 stromal interaction molecule 1
STON1 stonin 1
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TBC1D17 TBC1 domain family, member 17
TBX19 T-box 19
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TLN1 talin 1
TM7SF2 transmembrane 7 superfamily member 2
TM7SF3 transmembrane 7 superfamily member 3
TNNT1 troponin T type 1 (skeletal, slow)
TRIP10 thyroid hormone receptor interactor 10
UNKL unkempt family zinc finger-like
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VASP vasodilator-stimulated phosphoprotein
WBP2 WW domain binding protein 2
WBSCR16 Williams-Beuren syndrome chromosome region 16
WT1-AS WT1 antisense RNA
ZNF223 zinc finger protein 223
ZNF250 zinc finger protein 250
ZNF787 zinc finger protein 787
ZNF862 zinc finger protein 862