donepezil Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description Donepezil is a centrally acting reversible acetyl cholinesterase inhibitor. Its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine. (Chemical Entities of Biological Interest Ontology, CHEBI_53289)
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Genes

5 genes co-occuring with the biological term donepezil in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACHE acetylcholinesterase (Yt blood group)
APOE apolipoprotein E
BCHE butyrylcholinesterase
CHAT choline O-acetyltransferase
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6