dorzolamide Gene Set

Dataset Guide to Pharmacology Chemical Ligands of Receptors
Category physical interactions
Type ligand (chemical)
Description 5,6-Dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide in which hydrogens at the 4 and 6 positions are substituted by ethylamino and methyl groups, respectively (4S, trans-configuration). A carbonic anhydrase inhibitor, it is used as the hydrochloride in ophthalmic solutions to lower increased intraocular pressure in the treatment of open-angle glaucoma and ocular hypertension. (Chemical Entities of Biological Interest Ontology, CHEBI_4702)
External Link http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=6810
Similar Terms
Downloads & Tools

Genes

4 receptors of the dorzolamide ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

Symbol Name
CA1 carbonic anhydrase I
CA12 carbonic anhydrase XII
CA14 carbonic anhydrase XIV
CA7 carbonic anhydrase VII