dosedependent Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

274 genes co-occuring with the biological term dosedependent in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACHE acetylcholinesterase (Yt blood group)
ADRB1 adrenoceptor beta 1
AGER advanced glycosylation end product-specific receptor
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALAD aminolevulinate dehydratase
ALB albumin
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ANGPT1 angiopoietin 1
ANGPT2 angiopoietin 2
ANXA5 annexin A5
APCS amyloid P component, serum
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
APOC3 apolipoprotein C-III
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
BAD BCL2-associated agonist of cell death
BAX BCL2-associated X protein
BCL3 B-cell CLL/lymphoma 3
BIRC2 baculoviral IAP repeat containing 2
BIRC5 baculoviral IAP repeat containing 5
BMP2 bone morphogenetic protein 2
BMP4 bone morphogenetic protein 4
BMP7 bone morphogenetic protein 7
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRMS1 breast cancer metastasis suppressor 1
BST2 bone marrow stromal cell antigen 2
CALCRL calcitonin receptor-like
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CCL2 chemokine (C-C motif) ligand 2
CCL5 chemokine (C-C motif) ligand 5
CCND1 cyclin D1
CCR7 chemokine (C-C motif) receptor 7
CD274 CD274 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD81 CD81 molecule
CD83 CD83 molecule
CDC25C cell division cycle 25C
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2AIP CDKN2A interacting protein
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CFH complement factor H
CGA glycoprotein hormones, alpha polypeptide
CHGB chromogranin B
CLU clusterin
COL18A1 collagen, type XVIII, alpha 1
COL3A1 collagen, type III, alpha 1
COL8A2 collagen, type VIII, alpha 2
CREBBP CREB binding protein
CRP C-reactive protein, pentraxin-related
CTCF CCCTC-binding factor (zinc finger protein)
CTGF connective tissue growth factor
CTNND1 catenin (cadherin-associated protein), delta 1
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL8 chemokine (C-X-C motif) ligand 8
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR3 chemokine (C-X-C motif) receptor 3
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DEFA1 defensin, alpha 1
DEFB4A defensin, beta 4A
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
DLX3 distal-less homeobox 3
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DRD1 dopamine receptor D1
EDN1 endothelin 1
EGR1 early growth response 1
ELK1 ELK1, member of ETS oncogene family
ELN elastin
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
ERBB2 erb-b2 receptor tyrosine kinase 2
ERCC2 excision repair cross-complementation group 2
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
F2 coagulation factor II (thrombin)
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FGF21 fibroblast growth factor 21
FGFR1 fibroblast growth factor receptor 1
FLG filaggrin
FLT1 fms-related tyrosine kinase 1
FLT3LG fms-related tyrosine kinase 3 ligand
FN1 fibronectin 1
FOXO1 forkhead box O1
FOXO4 forkhead box O4
FOXP3 forkhead box P3
FSHB follicle stimulating hormone, beta polypeptide
FURIN furin (paired basic amino acid cleaving enzyme)
GADD45A growth arrest and DNA-damage-inducible, alpha
GARS glycyl-tRNA synthetase
GCK glucokinase (hexokinase 4)
GCKR glucokinase (hexokinase 4) regulator
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type
GH1 growth hormone 1
GIPC1 GIPC PDZ domain containing family, member 1
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GNRHR gonadotropin-releasing hormone receptor
GRP gastrin-releasing peptide
GSTA1 glutathione S-transferase alpha 1
HDAC1 histone deacetylase 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-B major histocompatibility complex, class I, B
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HMGB1 high mobility group box 1
HTN3 histatin 3
ICAM1 intercellular adhesion molecule 1
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IER3IP1 immediate early response 3 interacting protein 1
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFBP1 insulin-like growth factor binding protein 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP4 insulin-like growth factor binding protein 4
IL17A interleukin 17A
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL24 interleukin 24
IL4 interleukin 4
IL6 interleukin 6
INHBA inhibin, beta A
INS insulin
INSR insulin receptor
IRF4 interferon regulatory factor 4
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
JUN jun proto-oncogene
KRT17 keratin 17, type I
KRT18 keratin 18, type I
L1CAM L1 cell adhesion molecule
LAMC3 laminin, gamma 3
LCN2 lipocalin 2
LEP leptin
LIPG lipase, endothelial
LTF lactotransferrin
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MCL1 myeloid cell leukemia 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MECOM MDS1 and EVI1 complex locus
MGMT O-6-methylguanine-DNA methyltransferase
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR146B microRNA 146b
MIR17HG miR-17-92 cluster host gene
MIR449A microRNA 449a
MLH1 mutL homolog 1
MMP1 matrix metallopeptidase 1
MMP12 matrix metallopeptidase 12
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
MSH2 mutS homolog 2
MYC v-myc avian myelocytomatosis viral oncogene homolog
NCOR1 nuclear receptor corepressor 1
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFE2L2 nuclear factor, erythroid 2-like 2
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NKX3-2 NK3 homeobox 2
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NOS3 nitric oxide synthase 3 (endothelial cell)
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PARK2 parkin RBR E3 ubiquitin protein ligase
PARP1 poly (ADP-ribose) polymerase 1
PCSK5 proprotein convertase subtilisin/kexin type 5
PCSK7 proprotein convertase subtilisin/kexin type 7
PGR progesterone receptor
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIM3 Pim-3 proto-oncogene, serine/threonine kinase
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLAU plasminogen activator, urokinase
PLAUR plasminogen activator, urokinase receptor
PLTP phospholipid transfer protein
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
PON1 paraoxonase 1
POU5F1P3 POU class 5 homeobox 1 pseudogene 3
PPARG peroxisome proliferator-activated receptor gamma
PRDX1 peroxiredoxin 1
PRKCB protein kinase C, beta
PRKG1 protein kinase, cGMP-dependent, type I
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator
PRL prolactin
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PROX1 prospero homeobox 1
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTH1R parathyroid hormone 1 receptor
PTK6 protein tyrosine kinase 6
PTX3 pentraxin 3, long
PXN paxillin
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RAMP2 receptor (G protein-coupled) activity modifying protein 2
RCAN1 regulator of calcineurin 1
RECQL5 RecQ protein-like 5
RET ret proto-oncogene
RHO rhodopsin
RHOA ras homolog family member A
RLIM ring finger protein, LIM domain interacting
RNF114 ring finger protein 114
RNU1-1 RNA, U1 small nuclear 1
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
RSF1 remodeling and spacing factor 1
S100A6 S100 calcium binding protein A6
S100A9 S100 calcium binding protein A9
SAA1 serum amyloid A1
SCARB1 scavenger receptor class B, member 1
SELE selectin E
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SFN stratifin
SHANK2 SH3 and multiple ankyrin repeat domains 2
SIX1 SIX homeobox 1
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC22A12 solute carrier family 22 (organic anion/urate transporter), member 12
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNX6 sorting nexin 6
SOD1 superoxide dismutase 1, soluble
SOX9 SRY (sex determining region Y)-box 9
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome)
SPP1 secreted phosphoprotein 1
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
SREBF1 sterol regulatory element binding transcription factor 1
SREK1 splicing regulatory glutamine/lysine-rich protein 1
STAB2 stabilin 2
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TAC1 tachykinin, precursor 1
TARDBP TAR DNA binding protein
TBXA2R thromboxane A2 receptor
TEK TEK tyrosine kinase, endothelial
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TLR4 toll-like receptor 4
TLR7 toll-like receptor 7
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TP53 tumor protein p53
TP73 tumor protein p73
TPT1 tumor protein, translationally-controlled 1
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
VCAM1 vascular cell adhesion molecule 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
WNT3A wingless-type MMTV integration site family, member 3A