| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the dosulepin-2864 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADCY10 | adenylate cyclase 10 (soluble) |
| ADGRA2 | adhesion G protein-coupled receptor A2 |
| AHNAK2 | AHNAK nucleoprotein 2 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ARC | activity-regulated cytoskeleton-associated protein |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 |
| BEGAIN | brain-enriched guanylate kinase-associated |
| C17ORF59 | chromosome 17 open reading frame 59 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit |
| CD177 | CD177 molecule |
| CD34 | CD34 molecule |
| CD82 | CD82 molecule |
| CDO1 | cysteine dioxygenase type 1 |
| CEP164 | centrosomal protein 164kDa |
| CLEC4E | C-type lectin domain family 4, member E |
| CNTLN | centlein, centrosomal protein |
| COL1A1 | collagen, type I, alpha 1 |
| CTSF | cathepsin F |
| CYHR1 | cysteine/histidine-rich 1 |
| DAPK1 | death-associated protein kinase 1 |
| DMBT1 | deleted in malignant brain tumors 1 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DPF1 | D4, zinc and double PHD fingers family 1 |
| EGFL7 | EGF-like-domain, multiple 7 |
| ERP44 | endoplasmic reticulum protein 44 |
| ETV7 | ets variant 7 |
| FAM174B | family with sequence similarity 174, member B |
| FBXO2 | F-box protein 2 |
| FGFR4 | fibroblast growth factor receptor 4 |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GCGR | glucagon receptor |
| GGT1 | gamma-glutamyltransferase 1 |
| GRM4 | glutamate receptor, metabotropic 4 |
| GRPR | gastrin-releasing peptide receptor |
| HFE | hemochromatosis |
| HIST1H3E | histone cluster 1, H3e |
| HIST1H3I | histone cluster 1, H3i |
| HRASLS2 | HRAS-like suppressor 2 |
| ICA1 | islet cell autoantigen 1, 69kDa |
| INSIG1 | insulin induced gene 1 |
| IRF1 | interferon regulatory factor 1 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 |
| KIAA0391 | KIAA0391 |
| KLF9 | Kruppel-like factor 9 |
| KRT38 | keratin 38, type I |
| KRTAP2-4 | keratin associated protein 2-4 |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LMNA | lamin A/C |
| MAGEA3 | melanoma antigen family A3 |
| MAPRE2 | microtubule-associated protein, RP/EB family, member 2 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MMP3 | matrix metallopeptidase 3 |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MX2 | MX dynamin-like GTPase 2 |
| MYLPF | myosin light chain, phosphorylatable, fast skeletal muscle |
| MYOD1 | myogenic differentiation 1 |
| NEUROD1 | neuronal differentiation 1 |
| NF1 | neurofibromin 1 |
| NOX1 | NADPH oxidase 1 |
| NPPA | natriuretic peptide A |
| NRTN | neurturin |
| NTF3 | neurotrophin 3 |
| OPCML | opioid binding protein/cell adhesion molecule-like |
| OSBPL2 | oxysterol binding protein-like 2 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PGLYRP4 | peptidoglycan recognition protein 4 |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLLP | plasmolipin |
| POU5F1B | POU class 5 homeobox 1B |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 |
| PQLC2 | PQ loop repeat containing 2 |
| RAP2B | RAP2B, member of RAS oncogene family |
| RARA | retinoic acid receptor, alpha |
| RARB | retinoic acid receptor, beta |
| RIMS3 | regulating synaptic membrane exocytosis 3 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RUNX1 | runt-related transcription factor 1 |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SDC2 | syndecan 2 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| SMC1A | structural maintenance of chromosomes 1A |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| STAT2 | signal transducer and activator of transcription 2, 113kDa |
| STXBP5L | syntaxin binding protein 5-like |
| TAF7L | TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa |
| TBC1D2 | TBC1 domain family, member 2 |
| USP22 | ubiquitin specific peptidase 22 |
| ZNF350 | zinc finger protein 350 |
| ZNF778 | zinc finger protein 778 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ACTL8 | actin-like 8 |
| ADRBK2 | adrenergic, beta, receptor kinase 2 |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| AMT | aminomethyltransferase |
| ANKEF1 | ankyrin repeat and EF-hand domain containing 1 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| C19ORF73 | chromosome 19 open reading frame 73 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C1ORF56 | chromosome 1 open reading frame 56 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CCDC69 | coiled-coil domain containing 69 |
| CHKB | choline kinase beta |
| CIC | capicua transcriptional repressor |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DCAF4 | DDB1 and CUL4 associated factor 4 |
| DNALI1 | dynein, axonemal, light intermediate chain 1 |
| FAM110B | family with sequence similarity 110, member B |
| FAM189A2 | family with sequence similarity 189, member A2 |
| FBXL2 | F-box and leucine-rich repeat protein 2 |
| FGF23 | fibroblast growth factor 23 |
| FILIP1L | filamin A interacting protein 1-like |
| FOSL1 | FOS-like antigen 1 |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 |
| HEY2 | hes-related family bHLH transcription factor with YRPW motif 2 |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2BO | histone cluster 1, H2bo |
| HIST1H3B | histone cluster 1, H3b |
| HIST1H4E | histone cluster 1, H4e |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IL17RA | interleukin 17 receptor A |
| INPP1 | inositol polyphosphate-1-phosphatase |
| IQCG | IQ motif containing G |
| ITPKC | inositol-trisphosphate 3-kinase C |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 |
| KIAA0754 | KIAA0754 |
| KIF13B | kinesin family member 13B |
| KLHL36 | kelch-like family member 36 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LRP5 | low density lipoprotein receptor-related protein 5 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MAP1S | microtubule-associated protein 1S |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MGC12488 | |
| MON1B | MON1 secretory trafficking family member B |
| MT1H | metallothionein 1H |
| MTERF4 | mitochondrial transcription termination factor 4 |
| MYOZ3 | myozenin 3 |
| NKX3-2 | NK3 homeobox 2 |
| NOL10 | nucleolar protein 10 |
| NUS1P3 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3 |
| POLH | polymerase (DNA directed), eta |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRR4 | proline rich 4 (lacrimal) |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PSKH1 | protein serine kinase H1 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RAB3D | RAB3D, member RAS oncogene family |
| RETN | resistin |
| RIN2 | Ras and Rab interactor 2 |
| RPAP1 | RNA polymerase II associated protein 1 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SHPK | sedoheptulokinase |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 |
| SLC16A2 | solute carrier family 16, member 2 (thyroid hormone transporter) |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SMAD7 | SMAD family member 7 |
| SP1 | Sp1 transcription factor |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| TFF2 | trefoil factor 2 |
| TH | tyrosine hydroxylase |
| TMOD1 | tropomodulin 1 |
| TRIM36 | tripartite motif containing 36 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| TSGA10 | testis specific, 10 |
| TSPAN5 | tetraspanin 5 |
| TTC30A | tetratricopeptide repeat domain 30A |
| VEGFC | vascular endothelial growth factor C |
| WDR33 | WD repeat domain 33 |
| XAB2 | XPA binding protein 2 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| YARS2 | tyrosyl-tRNA synthetase 2, mitochondrial |
| ZNF268 | zinc finger protein 268 |
| ZNF324 | zinc finger protein 324 |
| ZNF329 | zinc finger protein 329 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF480 | zinc finger protein 480 |
| ZNF668 | zinc finger protein 668 |
| ZNF747 | zinc finger protein 747 |
