| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the dosulepin-5986 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ACRV1 | acrosomal vesicle protein 1 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| AOAH | acyloxyacyl hydrolase (neutrophil) |
| APOC1 | apolipoprotein C-I |
| APP | amyloid beta (A4) precursor protein |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ARL4C | ADP-ribosylation factor-like 4C |
| ATF6B | activating transcription factor 6 beta |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CCL16 | chemokine (C-C motif) ligand 16 |
| CCL23 | chemokine (C-C motif) ligand 23 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CLEC4E | C-type lectin domain family 4, member E |
| CNPY4 | canopy FGF signaling regulator 4 |
| CRY2 | cryptochrome circadian clock 2 |
| CTSS | cathepsin S |
| DCAF4 | DDB1 and CUL4 associated factor 4 |
| DGKI | diacylglycerol kinase, iota |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DMPK | dystrophia myotonica-protein kinase |
| DOCK9 | dedicator of cytokinesis 9 |
| EBI3 | Epstein-Barr virus induced 3 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa |
| EPHB2 | EPH receptor B2 |
| ETV7 | ets variant 7 |
| FADS3 | fatty acid desaturase 3 |
| FAM174B | family with sequence similarity 174, member B |
| FBXO4 | F-box protein 4 |
| FLT3LG | fms-related tyrosine kinase 3 ligand |
| FNTB | farnesyltransferase, CAAX box, beta |
| FYB | FYN binding protein |
| GALC | galactosylceramidase |
| GAS7 | growth arrest-specific 7 |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GPSM3 | G-protein signaling modulator 3 |
| HIPK3 | homeodomain interacting protein kinase 3 |
| HIST1H3F | histone cluster 1, H3f |
| HOXC5 | homeobox C5 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| IRF4 | interferon regulatory factor 4 |
| KCNH1 | potassium channel, voltage gated eag related subfamily H, member 1 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KHDRBS2 | KH domain containing, RNA binding, signal transduction associated 2 |
| KLHL35 | kelch-like family member 35 |
| LAMA4 | laminin, alpha 4 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAPK14 | mitogen-activated protein kinase 14 |
| MAPT | microtubule-associated protein tau |
| MSI1 | musashi RNA-binding protein 1 |
| NADK | NAD kinase |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NNAT | neuronatin |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| OR10C1 | olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene) |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PLD1 | phospholipase D1, phosphatidylcholine-specific |
| PLXNA3 | plexin A3 |
| PPP1R3A | protein phosphatase 1, regulatory subunit 3A |
| PRDM11 | PR domain containing 11 |
| PRKCA | protein kinase C, alpha |
| PTPRJ | protein tyrosine phosphatase, receptor type, J |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RALGPS1 | Ral GEF with PH domain and SH3 binding motif 1 |
| RARA | retinoic acid receptor, alpha |
| RNF39 | ring finger protein 39 |
| RPL10 | ribosomal protein L10 |
| RS1 | retinoschisin 1 |
| SECTM1 | secreted and transmembrane 1 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
| SH2B3 | SH2B adaptor protein 3 |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC35E2 | solute carrier family 35, member E2 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| SUGP1 | SURP and G patch domain containing 1 |
| TAS2R10 | taste receptor, type 2, member 10 |
| TCF3 | transcription factor 3 |
| TEF | thyrotrophic embryonic factor |
| TFAP2B | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) |
| TMEM63A | transmembrane protein 63A |
| TMPRSS2 | transmembrane protease, serine 2 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
| TNK2 | tyrosine kinase, non-receptor, 2 |
| TREM1 | triggering receptor expressed on myeloid cells 1 |
| TRPM1 | transient receptor potential cation channel, subfamily M, member 1 |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| TUBA3C | tubulin, alpha 3c |
| YY2 | YY2 transcription factor |
| ZNF419 | zinc finger protein 419 |
| Symbol | Name |
|---|---|
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ADAM15 | ADAM metallopeptidase domain 15 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| AMT | aminomethyltransferase |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ARNTL2 | aryl hydrocarbon receptor nuclear translocator-like 2 |
| BAG4 | BCL2-associated athanogene 4 |
| BBC3 | BCL2 binding component 3 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C2ORF68 | chromosome 2 open reading frame 68 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CCNO | cyclin O |
| CD82 | CD82 molecule |
| CHKB | choline kinase beta |
| CHML | choroideremia-like (Rab escort protein 2) |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CNN2 | calponin 2 |
| CRYBG3 | beta-gamma crystallin domain containing 3 |
| DCAF16 | DDB1 and CUL4 associated factor 16 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DEAF1 | DEAF1 transcription factor |
| DRD1 | dopamine receptor D1 |
| DSPP | dentin sialophosphoprotein |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| ERCC4 | excision repair cross-complementation group 4 |
| FBRS | fibrosin |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GMPR | guanosine monophosphate reductase |
| GPATCH2L | G patch domain containing 2-like |
| GPR19 | G protein-coupled receptor 19 |
| GPR27 | G protein-coupled receptor 27 |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IPP | intracisternal A particle-promoted polypeptide |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 |
| LOC100287590 | uncharacterized LOC100287590 |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| LRRC61 | leucine rich repeat containing 61 |
| MED9 | mediator complex subunit 9 |
| MFAP2 | microfibrillar-associated protein 2 |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MPHOSPH8 | M-phase phosphoprotein 8 |
| MVP | major vault protein |
| NDE1 | nudE neurodevelopment protein 1 |
| ONECUT2 | one cut homeobox 2 |
| PCDHA5 | protocadherin alpha 5 |
| PDE8B | phosphodiesterase 8B |
| PGPEP1 | pyroglutamyl-peptidase I |
| PHACTR4 | phosphatase and actin regulator 4 |
| PODXL2 | podocalyxin-like 2 |
| PRAF2 | PRA1 domain family, member 2 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog |
| RFWD3 | ring finger and WD repeat domain 3 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RNF2 | ring finger protein 2 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SETD1A | SET domain containing 1A |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SP1 | Sp1 transcription factor |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TCTN1 | tectonic family member 1 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM209 | transmembrane protein 209 |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) |
| UBQLN4 | ubiquilin 4 |
| USP20 | ubiquitin specific peptidase 20 |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| WDR4 | WD repeat domain 4 |
| WDR76 | WD repeat domain 76 |
| WFDC2 | WAP four-disulfide core domain 2 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 |
| ZNF160 | zinc finger protein 160 |
| ZNF35 | zinc finger protein 35 |
| ZNF428 | zinc finger protein 428 |
| ZNF652 | zinc finger protein 652 |
| ZNF665 | zinc finger protein 665 |
| ZNF721 | zinc finger protein 721 |
