| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the dosulepin-7284 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACACA | acetyl-CoA carboxylase alpha |
| AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| ASB1 | ankyrin repeat and SOCS box containing 1 |
| ASF1A | anti-silencing function 1A histone chaperone |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 |
| BRE | brain and reproductive organ-expressed (TNFRSF1A modulator) |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C17ORF85 | chromosome 17 open reading frame 85 |
| C1ORF21 | chromosome 1 open reading frame 21 |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CDC42EP2 | CDC42 effector protein (Rho GTPase binding) 2 |
| CLTB | clathrin, light chain B |
| CPN2 | carboxypeptidase N, polypeptide 2 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 |
| EDNRA | endothelin receptor type A |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) |
| FAS | Fas cell surface death receptor |
| FBXO46 | F-box protein 46 |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) |
| FH | fumarate hydratase |
| FLJ11292 | |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| GAD1 | glutamate decarboxylase 1 (brain, 67kDa) |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GPATCH4 | G patch domain containing 4 |
| GPR107 | G protein-coupled receptor 107 |
| GPR17 | G protein-coupled receptor 17 |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| HDAC11 | histone deacetylase 11 |
| HOMER3 | homer scaffolding protein 3 |
| IFIH1 | interferon induced with helicase C domain 1 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IGHD | immunoglobulin heavy constant delta |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| INPP5B | inositol polyphosphate-5-phosphatase, 75kDa |
| INSIG1 | insulin induced gene 1 |
| ITM2B | integral membrane protein 2B |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KDM5A | lysine (K)-specific demethylase 5A |
| KDM6A | lysine (K)-specific demethylase 6A |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIAA0513 | KIAA0513 |
| KIAA1467 | KIAA1467 |
| KIF1A | kinesin family member 1A |
| KPNA5 | karyopherin alpha 5 (importin alpha 6) |
| KRT34 | keratin 34, type I |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| LTC4S | leukotriene C4 synthase |
| MARS | methionyl-tRNA synthetase |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MMRN2 | multimerin 2 |
| MUC7 | mucin 7, secreted |
| NDE1 | nudE neurodevelopment protein 1 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
| NINJ1 | ninjurin 1 |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PDGFB | platelet-derived growth factor beta polypeptide |
| PGK1 | phosphoglycerate kinase 1 |
| PKP3 | plakophilin 3 |
| PMCH | pro-melanin-concentrating hormone |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 |
| PTPRF | protein tyrosine phosphatase, receptor type, F |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RPS3A | ribosomal protein S3A |
| RUNDC3B | RUN domain containing 3B |
| SAMD4A | sterile alpha motif domain containing 4A |
| SCG5 | secretogranin V |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SCN8A | sodium channel, voltage gated, type VIII alpha subunit |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) |
| SH3BP2 | SH3-domain binding protein 2 |
| SIAH1 | siah E3 ubiquitin protein ligase 1 |
| SLC1A7 | solute carrier family 1 (glutamate transporter), member 7 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SP100 | SP100 nuclear antigen |
| SPSB3 | splA/ryanodine receptor domain and SOCS box containing 3 |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| STC2 | stanniocalcin 2 |
| TLX2 | T-cell leukemia homeobox 2 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TOX | thymocyte selection-associated high mobility group box |
| TSPAN2 | tetraspanin 2 |
| USF2 | upstream transcription factor 2, c-fos interacting |
| VDAC3 | voltage-dependent anion channel 3 |
| WIPF1 | WAS/WASL interacting protein family, member 1 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZNF222 | zinc finger protein 222 |
| ZNF44 | zinc finger protein 44 |
| ZNF609 | zinc finger protein 609 |
| ZNF783 | zinc finger family member 783 |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ABHD8 | abhydrolase domain containing 8 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| APOO | apolipoprotein O |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 |
| BBS1 | Bardet-Biedl syndrome 1 |
| BEX1 | brain expressed, X-linked 1 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| C1ORF56 | chromosome 1 open reading frame 56 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CAMTA2 | calmodulin binding transcription activator 2 |
| CCNJL | cyclin J-like |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CENPB | centromere protein B, 80kDa |
| CENPT | centromere protein T |
| CHML | choroideremia-like (Rab escort protein 2) |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CLEC16A | C-type lectin domain family 16, member A |
| COG4 | component of oligomeric golgi complex 4 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DLK1 | delta-like 1 homolog (Drosophila) |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| DTWD1 | DTW domain containing 1 |
| DYNC1I1 | dynein, cytoplasmic 1, intermediate chain 1 |
| ENTPD3 | ectonucleoside triphosphate diphosphohydrolase 3 |
| EPHA4 | EPH receptor A4 |
| FAM50B | family with sequence similarity 50, member B |
| FANCC | Fanconi anemia, complementation group C |
| FKBP8 | FK506 binding protein 8, 38kDa |
| FPGS | folylpolyglutamate synthase |
| GPALPP1 | GPALPP motifs containing 1 |
| GPR39 | G protein-coupled receptor 39 |
| HIRA | histone cell cycle regulator |
| HSD3B2 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 |
| IL11RA | interleukin 11 receptor, alpha |
| IRF6 | interferon regulatory factor 6 |
| JMJD4 | jumonji domain containing 4 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KIFC1 | kinesin family member C1 |
| KLHL26 | kelch-like family member 26 |
| KLK5 | kallikrein-related peptidase 5 |
| KRT4 | keratin 4, type II |
| LPAR6 | lysophosphatidic acid receptor 6 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MANBA | mannosidase, beta A, lysosomal |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MCMBP | minichromosome maintenance complex binding protein |
| MED18 | mediator complex subunit 18 |
| METTL16 | methyltransferase like 16 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MFSD10 | major facilitator superfamily domain containing 10 |
| NCSTN | nicastrin |
| NXPH4 | neurexophilin 4 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PALMD | palmdelphin |
| PEG3 | paternally expressed 3 |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| POLR1B | polymerase (RNA) I polypeptide B, 128kDa |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| PSKH1 | protein serine kinase H1 |
| PSMD7 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 |
| PTGFR | prostaglandin F receptor (FP) |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 |
| RAB4B | RAB4B, member RAS oncogene family |
| RASA2 | RAS p21 protein activator 2 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SCYL2 | SCY1-like 2 (S. cerevisiae) |
| SLC12A8 | solute carrier family 12, member 8 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SPAG4 | sperm associated antigen 4 |
| SREBF1 | sterol regulatory element binding transcription factor 1 |
| STAR | steroidogenic acute regulatory protein |
| SUGCT | succinyl-CoA:glutarate-CoA transferase |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| SYTL2 | synaptotagmin-like 2 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TCTN2 | tectonic family member 2 |
| TH | tyrosine hydroxylase |
| TMEM209 | transmembrane protein 209 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TUBA3C | tubulin, alpha 3c |
| UNC119 | unc-119 homolog (C. elegans) |
| USP18 | ubiquitin specific peptidase 18 |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| ZNF273 | zinc finger protein 273 |
| ZNF385D | zinc finger protein 385D |
| ZNF84 | zinc finger protein 84 |
