| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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193 genes differentially expressed following the doxazosin-3024 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ABHD6 | abhydrolase domain containing 6 |
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADRBK1 | adrenergic, beta, receptor kinase 1 |
| AGFG2 | ArfGAP with FG repeats 2 |
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| C21ORF2 | chromosome 21 open reading frame 2 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CCDC85B | coiled-coil domain containing 85B |
| CCSER2 | coiled-coil serine-rich protein 2 |
| CD84 | CD84 molecule |
| CDCP1 | CUB domain containing protein 1 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLDN17 | claudin 17 |
| CLDN9 | claudin 9 |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CRAT | carnitine O-acetyltransferase |
| CREM | cAMP responsive element modulator |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
| DNASE2 | deoxyribonuclease II, lysosomal |
| DNMBP | dynamin binding protein |
| DOC2B | double C2-like domains, beta |
| DUSP4 | dual specificity phosphatase 4 |
| EMP1 | epithelial membrane protein 1 |
| EPHA4 | EPH receptor A4 |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FLT1 | fms-related tyrosine kinase 1 |
| FMO6P | flavin containing monooxygenase 6 pseudogene |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| GAS2 | growth arrest-specific 2 |
| GK3P | glycerol kinase 3 pseudogene |
| GPRC5C | G protein-coupled receptor, class C, group 5, member C |
| HIST1H4B | histone cluster 1, H4b |
| ICAM1 | intercellular adhesion molecule 1 |
| ICAM5 | intercellular adhesion molecule 5, telencephalin |
| IFI6 | interferon, alpha-inducible protein 6 |
| IL12RB2 | interleukin 12 receptor, beta 2 |
| INA | internexin neuronal intermediate filament protein, alpha |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| IRS4 | insulin receptor substrate 4 |
| ITIH3 | inter-alpha-trypsin inhibitor heavy chain 3 |
| IZUMO4 | IZUMO family member 4 |
| KCNMB2 | potassium channel subfamily M regulatory beta subunit 2 |
| KIAA0040 | KIAA0040 |
| KIR3DX1 | killer cell immunoglobulin-like receptor, three domains, X1 |
| KLF12 | Kruppel-like factor 12 |
| KLHL35 | kelch-like family member 35 |
| LAMA5 | laminin, alpha 5 |
| LAMC3 | laminin, gamma 3 |
| LIG3 | ligase III, DNA, ATP-dependent |
| LILRA2 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 |
| LILRA6 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 |
| LOC730101 | uncharacterized LOC730101 |
| LRRC36 | leucine rich repeat containing 36 |
| MISP | mitotic spindle positioning |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 |
| NRP1 | neuropilin 1 |
| OPRL1 | opiate receptor-like 1 |
| OSBPL10 | oxysterol binding protein-like 10 |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 |
| PGBD5 | piggyBac transposable element derived 5 |
| PIGR | polymeric immunoglobulin receptor |
| RECQL5 | RecQ protein-like 5 |
| RELN | reelin |
| RGS5 | regulator of G-protein signaling 5 |
| RHOH | ras homolog family member H |
| RIPPLY3 | ripply transcriptional repressor 3 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SAFB | scaffold attachment factor B |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SEC14L4 | SEC14-like 4 (S. cerevisiae) |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SP4 | Sp4 transcription factor |
| SPPL2B | signal peptide peptidase like 2B |
| SPTBN4 | spectrin, beta, non-erythrocytic 4 |
| TAS2R16 | taste receptor, type 2, member 16 |
| TCP10 | t-complex 10 |
| TDRD12 | tudor domain containing 12 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
| TRAF1 | TNF receptor-associated factor 1 |
| TRIM29 | tripartite motif containing 29 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 |
| TXNRD3 | thioredoxin reductase 3 |
| UNC119 | unc-119 homolog (C. elegans) |
| USP29 | ubiquitin specific peptidase 29 |
| VAV2 | vav 2 guanine nucleotide exchange factor |
| ZNF276 | zinc finger protein 276 |
| ZNF639 | zinc finger protein 639 |
| Symbol | Name |
|---|---|
| ABCC6 | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 |
| ACPP | acid phosphatase, prostate |
| ADTRP | androgen-dependent TFPI-regulating protein |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ARMCX4 | armadillo repeat containing, X-linked 4 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| BACE1 | beta-site APP-cleaving enzyme 1 |
| BBC3 | BCL2 binding component 3 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| BRIX1 | BRX1, biogenesis of ribosomes |
| C5ORF45 | chromosome 5 open reading frame 45 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CASS4 | Cas scaffolding protein family member 4 |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CDR2 | cerebellar degeneration-related protein 2, 62kDa |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CLTCL1 | clathrin, heavy chain-like 1 |
| CROT | carnitine O-octanoyltransferase |
| CRTAP | cartilage associated protein |
| DCAF17 | DDB1 and CUL4 associated factor 17 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DEFB1 | defensin, beta 1 |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DSPP | dentin sialophosphoprotein |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| FAM120C | family with sequence similarity 120C |
| FAM204A | family with sequence similarity 204, member A |
| FKBP5 | FK506 binding protein 5 |
| FLJ21369 | uncharacterized protein FLJ21369 |
| FLT4 | fms-related tyrosine kinase 4 |
| GPR27 | G protein-coupled receptor 27 |
| HAMP | hepcidin antimicrobial peptide |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2BN | histone cluster 1, H2bn |
| HIST1H3B | histone cluster 1, H3b |
| ICK | intestinal cell (MAK-like) kinase |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| IL2 | interleukin 2 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| KIAA1456 | KIAA1456 |
| KLHL26 | kelch-like family member 26 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LMNB1 | lamin B1 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LY75 | lymphocyte antigen 75 |
| MANSC1 | MANSC domain containing 1 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MBTD1 | mbt domain containing 1 |
| MRPS18C | mitochondrial ribosomal protein S18C |
| MRPS27 | mitochondrial ribosomal protein S27 |
| MTSS1L | metastasis suppressor 1-like |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NCKAP1L | NCK-associated protein 1-like |
| NDE1 | nudE neurodevelopment protein 1 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| ODF2 | outer dense fiber of sperm tails 2 |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PLAT | plasminogen activator, tissue |
| PLTP | phospholipid transfer protein |
| PMFBP1 | polyamine modulated factor 1 binding protein 1 |
| POMGNT1 | protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) |
| PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) |
| PRSS53 | protease, serine, 53 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RAB13 | RAB13, member RAS oncogene family |
| RCAN3 | RCAN family member 3 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RHOBTB1 | Rho-related BTB domain containing 1 |
| SENP7 | SUMO1/sentrin specific peptidase 7 |
| SIL1 | SIL1 nucleotide exchange factor |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPATA1 | spermatogenesis associated 1 |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| ST8SIA4 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 |
| ST8SIA5 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TMEM212 | transmembrane protein 212 |
| TMEM38B | transmembrane protein 38B |
| TRAIP | TRAF interacting protein |
| TRDMT1 | tRNA aspartic acid methyltransferase 1 |
| UPK3A | uroplakin 3A |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZBTB3 | zinc finger and BTB domain containing 3 |
| ZNF286A | zinc finger protein 286A |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF529 | zinc finger protein 529 |
| ZNF668 | zinc finger protein 668 |
| ZNF76 | zinc finger protein 76 |
