| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the doxazosin-3363 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADD2 | adducin 2 (beta) |
| AGTPBP1 | ATP/GTP binding protein 1 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 |
| ANO1 | anoctamin 1, calcium activated chloride channel |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide |
| BIRC7 | baculoviral IAP repeat containing 7 |
| BLNK | B-cell linker |
| C11ORF16 | chromosome 11 open reading frame 16 |
| CALML3 | calmodulin-like 3 |
| CCDC57 | coiled-coil domain containing 57 |
| CFHR4 | complement factor H-related 4 |
| CHODL | chondrolectin |
| CHRNE | cholinergic receptor, nicotinic, epsilon (muscle) |
| CLCA2 | chloride channel accessory 2 |
| CLEC4M | C-type lectin domain family 4, member M |
| CYP4F12 | cytochrome P450, family 4, subfamily F, polypeptide 12 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 |
| DCN | decorin |
| DDX51 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DRD2 | dopamine receptor D2 |
| EFNB1 | ephrin-B1 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| EPHB6 | EPH receptor B6 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| FBXO4 | F-box protein 4 |
| FCN2 | ficolin (collagen/fibrinogen domain containing lectin) 2 |
| FHL1 | four and a half LIM domains 1 |
| FKBP6 | FK506 binding protein 6, 36kDa |
| FRMD8 | FERM domain containing 8 |
| FST | follistatin |
| FUT2 | fucosyltransferase 2 (secretor status included) |
| FUT4 | fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) |
| FZD5 | frizzled class receptor 5 |
| GLIPR1 | GLI pathogenesis-related 1 |
| H6PD | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) |
| HIPK2 | homeodomain interacting protein kinase 2 |
| HIST1H1T | histone cluster 1, H1t |
| IFNA17 | interferon, alpha 17 |
| IL1B | interleukin 1, beta |
| IL1RN | interleukin 1 receptor antagonist |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| IQCC | IQ motif containing C |
| KIAA0485 | uncharacterized LOC57235 |
| KIAA1456 | KIAA1456 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LMX1B | LIM homeobox transcription factor 1, beta |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAP1A | microtubule-associated protein 1A |
| MCAM | melanoma cell adhesion molecule |
| MID1 | midline 1 |
| MIR622 | microRNA 622 |
| MMP3 | matrix metallopeptidase 3 |
| MOBP | myelin-associated oligodendrocyte basic protein |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MUC3B | mucin 3B, cell surface associated |
| MYOZ3 | myozenin 3 |
| NELL2 | NEL-like 2 (chicken) |
| NNAT | neuronatin |
| NOP16 | NOP16 nucleolar protein |
| NPTX2 | neuronal pentraxin II |
| NUP214 | nucleoporin 214kDa |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF |
| PDE4C | phosphodiesterase 4C, cAMP-specific |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PLXNB1 | plexin B1 |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit |
| PRKACA | protein kinase, cAMP-dependent, catalytic, alpha |
| PROL1 | proline rich, lacrimal 1 |
| PRUNE2 | prune homolog 2 (Drosophila) |
| PVR | poliovirus receptor |
| RAB33A | RAB33A, member RAS oncogene family |
| RAB40C | RAB40C, member RAS oncogene family |
| RALGPS1 | Ral GEF with PH domain and SH3 binding motif 1 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 |
| RIF1 | replication timing regulatory factor 1 |
| RORC | RAR-related orphan receptor C |
| RPL10 | ribosomal protein L10 |
| RPS6KA6 | ribosomal protein S6 kinase, 90kDa, polypeptide 6 |
| S100A13 | S100 calcium binding protein A13 |
| SAG | S-antigen; retina and pineal gland (arrestin) |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SCNN1G | sodium channel, non voltage gated 1 gamma subunit |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SLCO1A2 | solute carrier organic anion transporter family, member 1A2 |
| SPON1 | spondin 1, extracellular matrix protein |
| TBX5 | T-box 5 |
| TEK | TEK tyrosine kinase, endothelial |
| TRIM29 | tripartite motif containing 29 |
| TRMT44 | tRNA methyltransferase 44 homolog (S. cerevisiae) |
| UBA6 | ubiquitin-like modifier activating enzyme 6 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 |
| USP22 | ubiquitin specific peptidase 22 |
| ZNF117 | zinc finger protein 117 |
| ZNF384 | zinc finger protein 384 |
| Symbol | Name |
|---|---|
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CAPN5 | calpain 5 |
| CCDC121 | coiled-coil domain containing 121 |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CLGN | calmegin |
| CNTN1 | contactin 1 |
| CPSF7 | cleavage and polyadenylation specific factor 7, 59kDa |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DAGLA | diacylglycerol lipase, alpha |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| ERCC6 | excision repair cross-complementation group 6 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 |
| FGF23 | fibroblast growth factor 23 |
| FHOD1 | formin homology 2 domain containing 1 |
| FRK | fyn-related Src family tyrosine kinase |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GLCE | glucuronic acid epimerase |
| GMPR | guanosine monophosphate reductase |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GPR143 | G protein-coupled receptor 143 |
| GPR21 | G protein-coupled receptor 21 |
| HIST1H2BO | histone cluster 1, H2bo |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HOXC8 | homeobox C8 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IL22 | interleukin 22 |
| IQCG | IQ motif containing G |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KAT2A | K(lysine) acetyltransferase 2A |
| KCNK5 | potassium channel, two pore domain subfamily K, member 5 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIAA0319L | KIAA0319-like |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| LAMP3 | lysosomal-associated membrane protein 3 |
| LHX1 | LIM homeobox 1 |
| MAGEA3 | melanoma antigen family A3 |
| MBIP | MAP3K12 binding inhibitory protein 1 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric |
| NDRG4 | NDRG family member 4 |
| NKX3-2 | NK3 homeobox 2 |
| NPTX1 | neuronal pentraxin I |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| PARD6A | par-6 family cell polarity regulator alpha |
| PEX26 | peroxisomal biogenesis factor 26 |
| PLCD1 | phospholipase C, delta 1 |
| POLM | polymerase (DNA directed), mu |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| PRAMEF11 | PRAME family member 11 |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| RAB5B | RAB5B, member RAS oncogene family |
| RFTN1 | raftlin, lipid raft linker 1 |
| RGS20 | regulator of G-protein signaling 20 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RNF208 | ring finger protein 208 |
| RPGRIP1L | RPGRIP1-like |
| RPL10L | ribosomal protein L10-like |
| S100A9 | S100 calcium binding protein A9 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SHARPIN | SHANK-associated RH domain interactor |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SOX3 | SRY (sex determining region Y)-box 3 |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STIM1 | stromal interaction molecule 1 |
| STX1A | syntaxin 1A (brain) |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TBC1D2 | TBC1 domain family, member 2 |
| TET3 | tet methylcytosine dioxygenase 3 |
| TMC7 | transmembrane channel-like 7 |
| TMEM242 | transmembrane protein 242 |
| TMEM45A | transmembrane protein 45A |
| TMPRSS4 | transmembrane protease, serine 4 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TRIM21 | tripartite motif containing 21 |
| TSC22D4 | TSC22 domain family, member 4 |
| UPK2 | uroplakin 2 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZNF446 | zinc finger protein 446 |
| ZNF532 | zinc finger protein 532 |
| ZNF768 | zinc finger protein 768 |
| ZNF804A | zinc finger protein 804A |
