| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the doxazosin-4988 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) |
| ACSBG1 | acyl-CoA synthetase bubblegum family member 1 |
| AKAP4 | A kinase (PRKA) anchor protein 4 |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| ALDOB | aldolase B, fructose-bisphosphate |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 |
| ATF7IP | activating transcription factor 7 interacting protein |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CABIN1 | calcineurin binding protein 1 |
| CADM3 | cell adhesion molecule 3 |
| CCDC88A | coiled-coil domain containing 88A |
| CCR1 | chemokine (C-C motif) receptor 1 |
| CD22 | CD22 molecule |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DGCR2 | DiGeorge syndrome critical region gene 2 |
| DHRS12 | dehydrogenase/reductase (SDR family) member 12 |
| DMBT1 | deleted in malignant brain tumors 1 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) |
| ELSPBP1 | epididymal sperm binding protein 1 |
| ETV5 | ets variant 5 |
| EXOSC1 | exosome component 1 |
| FAM182B | family with sequence similarity 182, member B |
| FOXG1 | forkhead box G1 |
| FUS | FUS RNA binding protein |
| GDF5 | growth differentiation factor 5 |
| GFER | growth factor, augmenter of liver regeneration |
| GNRH2 | gonadotropin-releasing hormone 2 |
| HCRP1 | hepatocellular carcinoma-related HCRP1 |
| HDLBP | high density lipoprotein binding protein |
| HIST1H3F | histone cluster 1, H3f |
| HOXB2 | homeobox B2 |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IL4R | interleukin 4 receptor |
| INHBA | inhibin, beta A |
| INSL5 | insulin-like 5 |
| IZUMO4 | IZUMO family member 4 |
| KIF21B | kinesin family member 21B |
| KIF5A | kinesin family member 5A |
| KITLG | KIT ligand |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LIMK1 | LIM domain kinase 1 |
| LPAR4 | lysophosphatidic acid receptor 4 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MBD2 | methyl-CpG binding domain protein 2 |
| MID1 | midline 1 |
| MIER2 | mesoderm induction early response 1, family member 2 |
| MIIP | migration and invasion inhibitory protein |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MMP25 | matrix metallopeptidase 25 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming |
| MYH14 | myosin, heavy chain 14, non-muscle |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NR0B2 | nuclear receptor subfamily 0, group B, member 2 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 |
| NUP214 | nucleoporin 214kDa |
| OGFR | opioid growth factor receptor |
| PAX8 | paired box 8 |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
| PLAC4 | placenta-specific 4 |
| POPDC3 | popeye domain containing 3 |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RGS20 | regulator of G-protein signaling 20 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SNN | stannin |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| SUGCT | succinyl-CoA:glutarate-CoA transferase |
| TBX2 | T-box 2 |
| TCP10L | t-complex 10-like |
| TEF | thyrotrophic embryonic factor |
| TK2 | thymidine kinase 2, mitochondrial |
| TLR2 | toll-like receptor 2 |
| TMEM53 | transmembrane protein 53 |
| TNN | tenascin N |
| TRIM14 | tripartite motif containing 14 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 |
| TTC9 | tetratricopeptide repeat domain 9 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| TTLL5 | tubulin tyrosine ligase-like family member 5 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| UCN | urocortin |
| UROD | uroporphyrinogen decarboxylase |
| VEGFB | vascular endothelial growth factor B |
| VIM | vimentin |
| ZFHX2 | zinc finger homeobox 2 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| APH1A | APH1A gamma secretase subunit |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ARMC6 | armadillo repeat containing 6 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| BBC3 | BCL2 binding component 3 |
| BCL9 | B-cell CLL/lymphoma 9 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C1ORF35 | chromosome 1 open reading frame 35 |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CCDC121 | coiled-coil domain containing 121 |
| CGA | glycoprotein hormones, alpha polypeptide |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CST6 | cystatin E/M |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
| DDB1 | damage-specific DNA binding protein 1, 127kDa |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DUSP2 | dual specificity phosphatase 2 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| EPPK1 | epiplakin 1 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| FAAH | fatty acid amide hydrolase |
| FER | fer (fps/fes related) tyrosine kinase |
| GCA | grancalcin, EF-hand calcium binding protein |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GPR1 | G protein-coupled receptor 1 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HDAC4 | histone deacetylase 4 |
| HMOX1 | heme oxygenase 1 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI6 | interferon, alpha-inducible protein 6 |
| KIAA0319L | KIAA0319-like |
| KLF11 | Kruppel-like factor 11 |
| LMBR1L | limb development membrane protein 1-like |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
| LRRC61 | leucine rich repeat containing 61 |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MED15 | mediator complex subunit 15 |
| MRPL2 | mitochondrial ribosomal protein L2 |
| MSMB | microseminoprotein, beta- |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MVP | major vault protein |
| NBEAL2 | neurobeachin-like 2 |
| NME5 | NME/NM23 family member 5 |
| PADI2 | peptidyl arginine deiminase, type II |
| PARD6A | par-6 family cell polarity regulator alpha |
| PDIA3 | protein disulfide isomerase family A, member 3 |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PKN1 | protein kinase N1 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PNPLA6 | patatin-like phospholipase domain containing 6 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRR14L | proline rich 14-like |
| PRRG2 | proline rich Gla (G-carboxyglutamic acid) 2 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 |
| RAB5B | RAB5B, member RAS oncogene family |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RECQL4 | RecQ protein-like 4 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| ROM1 | retinal outer segment membrane protein 1 |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SLC26A6 | solute carrier family 26 (anion exchanger), member 6 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SNHG3 | small nucleolar RNA host gene 3 |
| SPHK1 | sphingosine kinase 1 |
| SPIDR | scaffolding protein involved in DNA repair |
| SPRYD7 | SPRY domain containing 7 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TCTN1 | tectonic family member 1 |
| TRIM25 | tripartite motif containing 25 |
| TYW1 | tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| WDR13 | WD repeat domain 13 |
| WDR76 | WD repeat domain 76 |
| WDR82 | WD repeat domain 82 |
| XAB2 | XPA binding protein 2 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZNF551 | zinc finger protein 551 |
| ZNF767P | zinc finger family member 767, pseudogene |
| ZNF804A | zinc finger protein 804A |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |
