| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the doxazosin-6642 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADORA3 | adenosine A3 receptor |
| AFF2 | AF4/FMR2 family, member 2 |
| AGTR1 | angiotensin II receptor, type 1 |
| AIF1 | allograft inflammatory factor 1 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| APOA1 | apolipoprotein A-I |
| ARID5A | AT rich interactive domain 5A (MRF1-like) |
| ATP6V1G2 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 |
| AVPR1A | arginine vasopressin receptor 1A |
| BMP7 | bone morphogenetic protein 7 |
| BTG2 | BTG family, member 2 |
| C1QB | complement component 1, q subcomponent, B chain |
| CABP2 | calcium binding protein 2 |
| CARD10 | caspase recruitment domain family, member 10 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CD160 | CD160 molecule |
| CD6 | CD6 molecule |
| CD68 | CD68 molecule |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CEBPE | CCAAT/enhancer binding protein (C/EBP), epsilon |
| CLCA2 | chloride channel accessory 2 |
| CLIC2 | chloride intracellular channel 2 |
| CLTA | clathrin, light chain A |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
| DKKL1 | dickkopf-like 1 |
| DNAAF1 | dynein, axonemal, assembly factor 1 |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| E2F2 | E2F transcription factor 2 |
| EFNB3 | ephrin-B3 |
| EFS | embryonal Fyn-associated substrate |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| ERGIC3 | ERGIC and golgi 3 |
| FETUB | fetuin B |
| FFAR2 | free fatty acid receptor 2 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 |
| GNAS | GNAS complex locus |
| HBZ | hemoglobin, zeta |
| HDAC6 | histone deacetylase 6 |
| HGD | homogentisate 1,2-dioxygenase |
| HIST1H2AB | histone cluster 1, H2ab |
| IFFO1 | intermediate filament family orphan 1 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| JAK3 | Janus kinase 3 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KCNE2 | potassium channel, voltage gated subfamily E regulatory beta subunit 2 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KIF1C | kinesin family member 1C |
| KLK10 | kallikrein-related peptidase 10 |
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 |
| LGALS9 | lectin, galactoside-binding, soluble, 9 |
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
| MAPK8 | mitogen-activated protein kinase 8 |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| MTCP1 | mature T-cell proliferation 1 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NEIL1 | nei endonuclease VIII-like 1 (E. coli) |
| NEK9 | NIMA-related kinase 9 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| OR2H2 | olfactory receptor, family 2, subfamily H, member 2 |
| PAOX | polyamine oxidase (exo-N4-amino) |
| PBOV1 | prostate and breast cancer overexpressed 1 |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PKD2L2 | polycystic kidney disease 2-like 2 |
| PKN2 | protein kinase N2 |
| PLA2G10 | phospholipase A2, group X |
| PLCE1 | phospholipase C, epsilon 1 |
| POLL | polymerase (DNA directed), lambda |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A |
| PPP2CB | protein phosphatase 2, catalytic subunit, beta isozyme |
| PRAMEF10 | PRAME family member 10 |
| PTGDR | prostaglandin D2 receptor (DP) |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| RASAL2 | RAS protein activator like 2 |
| RGS6 | regulator of G-protein signaling 6 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) |
| RUNDC3A | RUN domain containing 3A |
| SEMA3G | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SLIT1 | slit homolog 1 (Drosophila) |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| SRP72 | signal recognition particle 72kDa |
| SSX3 | synovial sarcoma, X breakpoint 3 |
| TAPT1 | transmembrane anterior posterior transformation 1 |
| THOC5 | THO complex 5 |
| TLX3 | T-cell leukemia homeobox 3 |
| TMPRSS5 | transmembrane protease, serine 5 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TRIM46 | tripartite motif containing 46 |
| TRMT44 | tRNA methyltransferase 44 homolog (S. cerevisiae) |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 |
| WIZ | widely interspaced zinc finger motifs |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF639 | zinc finger protein 639 |
| Symbol | Name |
|---|---|
| ADAM15 | ADAM metallopeptidase domain 15 |
| ALPK1 | alpha-kinase 1 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATPAF2 | ATP synthase mitochondrial F1 complex assembly factor 2 |
| BCL2L2 | BCL2-like 2 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CDT1 | chromatin licensing and DNA replication factor 1 |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CPA4 | carboxypeptidase A4 |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DCLRE1A | DNA cross-link repair 1A |
| DNAL4 | dynein, axonemal, light chain 4 |
| DNMBP | dynamin binding protein |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| ERCC2 | excision repair cross-complementation group 2 |
| ETV4 | ets variant 4 |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FKBP5 | FK506 binding protein 5 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GPC3 | glypican 3 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| HAUS6 | HAUS augmin-like complex, subunit 6 |
| HOMER2 | homer scaffolding protein 2 |
| HOXA4 | homeobox A4 |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 |
| HYMAI | hydatidiform mole associated and imprinted (non-protein coding) |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa |
| IPO8 | importin 8 |
| LRIG2 | leucine-rich repeats and immunoglobulin-like domains 2 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MED31 | mediator complex subunit 31 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MITF | microphthalmia-associated transcription factor |
| MTA2 | metastasis associated 1 family, member 2 |
| MTMR11 | myotubularin related protein 11 |
| MYL9 | myosin, light chain 9, regulatory |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NKX3-2 | NK3 homeobox 2 |
| NME5 | NME/NM23 family member 5 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| POLM | polymerase (DNA directed), mu |
| POLR2F | polymerase (RNA) II (DNA directed) polypeptide F |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRKX | protein kinase, X-linked |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| PTPRH | protein tyrosine phosphatase, receptor type, H |
| RAB5B | RAB5B, member RAS oncogene family |
| RASA2 | RAS p21 protein activator 2 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit |
| ROM1 | retinal outer segment membrane protein 1 |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| SCD5 | stearoyl-CoA desaturase 5 |
| SCIN | scinderin |
| SEC14L2 | SEC14-like 2 (S. cerevisiae) |
| SENP7 | SUMO1/sentrin specific peptidase 7 |
| SIK1 | salt-inducible kinase 1 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC35C2 | solute carrier family 35 (GDP-fucose transporter), member C2 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SND1-IT1 | SND1 intronic transcript 1 |
| STAC | SH3 and cysteine rich domain |
| SYNPO | synaptopodin |
| TARS2 | threonyl-tRNA synthetase 2, mitochondrial (putative) |
| TDRD7 | tudor domain containing 7 |
| TENM1 | teneurin transmembrane protein 1 |
| TMEM121 | transmembrane protein 121 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TWISTNB | TWIST neighbor |
| WDR18 | WD repeat domain 18 |
| YOD1 | YOD1 deubiquitinase |
| ZNF141 | zinc finger protein 141 |
| ZNF214 | zinc finger protein 214 |
| ZNF253 | zinc finger protein 253 |
| ZNF276 | zinc finger protein 276 |
| ZNF574 | zinc finger protein 574 |
| ZNF671 | zinc finger protein 671 |
| ZNF747 | zinc finger protein 747 |
| ZNF768 | zinc finger protein 768 |
| ZW10 | zw10 kinetochore protein |
