doxazosin Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A member of the class of quinazolines that is quinazoline substituted by an amino group at position 4, methoxy groups at positions 6 and 7 and a piperazin-1-yl group at position 2 which in turn is substituted by a 2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl group at position 4. An antihypertensive agent, it is used in the treatment of high blood pressure. (Chemical Entities of Biological Interest Ontology, CHEBI_4708)
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Genes

9 genes co-occuring with the biological term doxazosin in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ADRA1A adrenoceptor alpha 1A
CFLAR CASP8 and FADD-like apoptosis regulator
CYBA cytochrome b-245, alpha polypeptide
HSPB1 heat shock 27kDa protein 1
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)