| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the doxepin-2384 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADD2 | adducin 2 (beta) |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| APOE | apolipoprotein E |
| ARRB2 | arrestin, beta 2 |
| B3GALNT1 | beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| C19ORF66 | chromosome 19 open reading frame 66 |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CD24 | CD24 molecule |
| CD59 | CD59 molecule, complement regulatory protein |
| CDHR2 | cadherin-related family member 2 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CLEC3B | C-type lectin domain family 3, member B |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa |
| CYHR1 | cysteine/histidine-rich 1 |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| DGCR2 | DiGeorge syndrome critical region gene 2 |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 |
| DOLK | dolichol kinase |
| EGR1 | early growth response 1 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| ENDOD1 | endonuclease domain containing 1 |
| FAM127B | family with sequence similarity 127, member B |
| FAM3A | family with sequence similarity 3, member A |
| FAM63B | family with sequence similarity 63, member B |
| FBXO40 | F-box protein 40 |
| FOXG1 | forkhead box G1 |
| FUT2 | fucosyltransferase 2 (secretor status included) |
| GABRA4 | gamma-aminobutyric acid (GABA) A receptor, alpha 4 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GLIPR1 | GLI pathogenesis-related 1 |
| GP6 | glycoprotein VI (platelet) |
| GPD2 | glycerol-3-phosphate dehydrogenase 2 (mitochondrial) |
| HEXIM1 | hexamethylene bis-acetamide inducible 1 |
| HFE | hemochromatosis |
| HHLA3 | HERV-H LTR-associating 3 |
| HOMER3 | homer scaffolding protein 3 |
| HOXA1 | homeobox A1 |
| HOXA4 | homeobox A4 |
| HOXD9 | homeobox D9 |
| HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
| ICA1 | islet cell autoantigen 1, 69kDa |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| INHBA | inhibin, beta A |
| INPP5K | inositol polyphosphate-5-phosphatase K |
| KDM4B | lysine (K)-specific demethylase 4B |
| KLF3 | Kruppel-like factor 3 (basic) |
| KLHL36 | kelch-like family member 36 |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| MAP3K12 | mitogen-activated protein kinase kinase kinase 12 |
| MAPK8 | mitogen-activated protein kinase 8 |
| MAPT | microtubule-associated protein tau |
| MATN1 | matrilin 1, cartilage matrix protein |
| MCOLN1 | mucolipin 1 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MST1 | macrophage stimulating 1 |
| NCLN | nicalin |
| NUDT13 | nudix (nucleoside diphosphate linked moiety X)-type motif 13 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor |
| PDE4D | phosphodiesterase 4D, cAMP-specific |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) |
| PLP1 | proteolipid protein 1 |
| PRDM1 | PR domain containing 1, with ZNF domain |
| PTPN2 | protein tyrosine phosphatase, non-receptor type 2 |
| PYGB | phosphorylase, glycogen; brain |
| QSER1 | glutamine and serine rich 1 |
| RASAL2 | RAS protein activator like 2 |
| RBKS | ribokinase |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RUNX1 | runt-related transcription factor 1 |
| RXRB | retinoid X receptor, beta |
| SAMD4A | sterile alpha motif domain containing 4A |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SRR | serine racemase |
| SSBP2 | single-stranded DNA binding protein 2 |
| STS | steroid sulfatase (microsomal), isozyme S |
| STX1A | syntaxin 1A (brain) |
| STX5 | syntaxin 5 |
| THRB | thyroid hormone receptor, beta |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TSC22D4 | TSC22 domain family, member 4 |
| ZNF185 | zinc finger protein 185 (LIM domain) |
| ZNF287 | zinc finger protein 287 |
| ZNF34 | zinc finger protein 34 |
| ZNF500 | zinc finger protein 500 |
| ZNF510 | zinc finger protein 510 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 |
| Symbol | Name |
|---|---|
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| ALDOC | aldolase C, fructose-bisphosphate |
| ALPK1 | alpha-kinase 1 |
| ALS2CL | ALS2 C-terminal like |
| ANKRD36 | ankyrin repeat domain 36 |
| APOBR | apolipoprotein B receptor |
| APOL6 | apolipoprotein L, 6 |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ARHGAP12 | Rho GTPase activating protein 12 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| ASPN | asporin |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C1ORF95 | chromosome 1 open reading frame 95 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CAPN5 | calpain 5 |
| CCDC176 | coiled-coil domain containing 176 |
| CCDC85C | coiled-coil domain containing 85C |
| CCNT1 | cyclin T1 |
| CD70 | CD70 molecule |
| CDA | cytidine deaminase |
| CIC | capicua transcriptional repressor |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CNPY4 | canopy FGF signaling regulator 4 |
| COLEC10 | collectin sub-family member 10 (C-type lectin) |
| CRYL1 | crystallin, lambda 1 |
| DDN | dendrin |
| DENND2D | DENN/MADD domain containing 2D |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EML4 | echinoderm microtubule associated protein like 4 |
| ERCC4 | excision repair cross-complementation group 4 |
| FAM102A | family with sequence similarity 102, member A |
| FAM204A | family with sequence similarity 204, member A |
| GALT | galactose-1-phosphate uridylyltransferase |
| GBF1 | golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
| GPR27 | G protein-coupled receptor 27 |
| HIST1H2AJ | histone cluster 1, H2aj |
| IFT46 | intraflagellar transport 46 |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| KLF1 | Kruppel-like factor 1 (erythroid) |
| KLHL26 | kelch-like family member 26 |
| L2HGDH | L-2-hydroxyglutarate dehydrogenase |
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 |
| LIN7B | lin-7 homolog B (C. elegans) |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| MCMBP | minichromosome maintenance complex binding protein |
| MED15 | mediator complex subunit 15 |
| MEGF8 | multiple EGF-like-domains 8 |
| MLC1 | megalencephalic leukoencephalopathy with subcortical cysts 1 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MTG1 | mitochondrial ribosome-associated GTPase 1 |
| MXD3 | MAX dimerization protein 3 |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NCS1 | neuronal calcium sensor 1 |
| NPFFR1 | neuropeptide FF receptor 1 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PDZD7 | PDZ domain containing 7 |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 |
| PODXL2 | podocalyxin-like 2 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RABL6 | RAB, member RAS oncogene family-like 6 |
| RGP1 | RGP1 retrograde golgi transport homolog (S. cerevisiae) |
| RNF31 | ring finger protein 31 |
| S1PR4 | sphingosine-1-phosphate receptor 4 |
| SHARPIN | SHANK-associated RH domain interactor |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SPATS2 | spermatogenesis associated, serine-rich 2 |
| STEAP3 | STEAP family member 3, metalloreductase |
| STXBP1 | syntaxin binding protein 1 |
| TET3 | tet methylcytosine dioxygenase 3 |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TMC7 | transmembrane channel-like 7 |
| TMEM187 | transmembrane protein 187 |
| TMEM209 | transmembrane protein 209 |
| TMOD3 | tropomodulin 3 (ubiquitous) |
| TMUB2 | transmembrane and ubiquitin-like domain containing 2 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TSPAN5 | tetraspanin 5 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| WARS2 | tryptophanyl tRNA synthetase 2, mitochondrial |
| ZC2HC1A | zinc finger, C2HC-type containing 1A |
| ZNF350 | zinc finger protein 350 |
| ZNF354A | zinc finger protein 354A |
| ZNF552 | zinc finger protein 552 |
