| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the doxepin-6337 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| ANGPTL2 | angiopoietin-like 2 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| ASPN | asporin |
| BBC3 | BCL2 binding component 3 |
| C21ORF2 | chromosome 21 open reading frame 2 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CALD1 | caldesmon 1 |
| CEACAM3 | carcinoembryonic antigen-related cell adhesion molecule 3 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| COL11A2 | collagen, type XI, alpha 2 |
| CYP2W1 | cytochrome P450, family 2, subfamily W, polypeptide 1 |
| DCTN1 | dynactin 1 |
| DENND3 | DENN/MADD domain containing 3 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| DVL2 | dishevelled segment polarity protein 2 |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| EGFR | epidermal growth factor receptor |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
| EMP1 | epithelial membrane protein 1 |
| ENTPD4 | ectonucleoside triphosphate diphosphohydrolase 4 |
| EPN3 | epsin 3 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| FGL1 | fibrinogen-like 1 |
| FNDC4 | fibronectin type III domain containing 4 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GRM4 | glutamate receptor, metabotropic 4 |
| GYPC | glycophorin C (Gerbich blood group) |
| HCRTR2 | hypocretin (orexin) receptor 2 |
| HIP1 | huntingtin interacting protein 1 |
| HIST1H2AK | histone cluster 1, H2ak |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
| HPN | hepsin |
| IDH3G | isocitrate dehydrogenase 3 (NAD+) gamma |
| IGHMBP2 | immunoglobulin mu binding protein 2 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon |
| KIAA1467 | KIAA1467 |
| KRT31 | keratin 31, type I |
| LDB3 | LIM domain binding 3 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MASP2 | mannan-binding lectin serine peptidase 2 |
| MED31 | mediator complex subunit 31 |
| MEF2D | myocyte enhancer factor 2D |
| MEFV | Mediterranean fever |
| METTL7A | methyltransferase like 7A |
| MXRA8 | matrix-remodelling associated 8 |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PCDHA6 | protocadherin alpha 6 |
| PDGFB | platelet-derived growth factor beta polypeptide |
| PHF7 | PHD finger protein 7 |
| PKP3 | plakophilin 3 |
| PLCL2 | phospholipase C-like 2 |
| PLD2 | phospholipase D2 |
| PRUNE2 | prune homolog 2 (Drosophila) |
| PTBP3 | polypyrimidine tract binding protein 3 |
| PTGES | prostaglandin E synthase |
| PTPN7 | protein tyrosine phosphatase, non-receptor type 7 |
| PXMP4 | peroxisomal membrane protein 4, 24kDa |
| RBM12B | RNA binding motif protein 12B |
| RFPL3 | ret finger protein-like 3 |
| RNF19B | ring finger protein 19B |
| ROR1 | receptor tyrosine kinase-like orphan receptor 1 |
| RUNX1-IT1 | RUNX1 intronic transcript 1 |
| S100A13 | S100 calcium binding protein A13 |
| SCARB1 | scavenger receptor class B, member 1 |
| SEMA4G | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G |
| SENP5 | SUMO1/sentrin specific peptidase 5 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SFRP4 | secreted frizzled-related protein 4 |
| SH2B1 | SH2B adaptor protein 1 |
| SIRT6 | sirtuin 6 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 |
| SLC6A2 | solute carrier family 6 (neurotransmitter transporter), member 2 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| ST8SIA3 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 |
| SYNDIG1 | synapse differentiation inducing 1 |
| TIMM8A | translocase of inner mitochondrial membrane 8 homolog A (yeast) |
| TMEM63A | transmembrane protein 63A |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TP53AIP1 | tumor protein p53 regulated apoptosis inducing protein 1 |
| TRAF3IP2 | TRAF3 interacting protein 2 |
| TRIM3 | tripartite motif containing 3 |
| UNC119 | unc-119 homolog (C. elegans) |
| USB1 | U6 snRNA biogenesis 1 |
| VWA5A | von Willebrand factor A domain containing 5A |
| XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 |
| ZIM2 | zinc finger, imprinted 2 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF75D | zinc finger protein 75D |
| ZNF778 | zinc finger protein 778 |
| Symbol | Name |
|---|---|
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| ALPK1 | alpha-kinase 1 |
| AP1B1 | adaptor-related protein complex 1, beta 1 subunit |
| APH1B | APH1B gamma secretase subunit |
| ARHGAP11A | Rho GTPase activating protein 11A |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| BEX1 | brain expressed, X-linked 1 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C1ORF112 | chromosome 1 open reading frame 112 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C1ORF56 | chromosome 1 open reading frame 56 |
| CABIN1 | calcineurin binding protein 1 |
| CCDC106 | coiled-coil domain containing 106 |
| CENPC | centromere protein C |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| DCLRE1B | DNA cross-link repair 1B |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| DOLK | dolichol kinase |
| EPHA4 | EPH receptor A4 |
| ERF | Ets2 repressor factor |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha |
| FPGS | folylpolyglutamate synthase |
| GMIP | GEM interacting protein |
| GPS1 | G protein pathway suppressor 1 |
| HHLA3 | HERV-H LTR-associating 3 |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H3G | histone cluster 1, H3g |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| IFT54 | intraflagellar transport 54 |
| IFT81 | intraflagellar transport 81 |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
| IRF2 | interferon regulatory factor 2 |
| JUNB | jun B proto-oncogene |
| KRT75 | keratin 75, type II |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LUC7L | LUC7-like (S. cerevisiae) |
| LY6E | lymphocyte antigen 6 complex, locus E |
| MAGEA6 | melanoma antigen family A6 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MAPK12 | mitogen-activated protein kinase 12 |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
| MOGS | mannosyl-oligosaccharide glucosidase |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| NOX5 | NADPH oxidase, EF-hand calcium binding domain 5 |
| NPY1R | neuropeptide Y receptor Y1 |
| NRSN2 | neurensin 2 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PAGR1 | PAXIP1 associated glutamate-rich protein 1 |
| PALMD | palmdelphin |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit |
| PARD6A | par-6 family cell polarity regulator alpha |
| PEX26 | peroxisomal biogenesis factor 26 |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRR3 | proline rich 3 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PRSS2 | protease, serine, 2 (trypsin 2) |
| PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) |
| RIPPLY3 | ripply transcriptional repressor 3 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SALL2 | spalt-like transcription factor 2 |
| SERPIND1 | serpin peptidase inhibitor, clade D (heparin cofactor), member 1 |
| SFT2D2 | SFT2 domain containing 2 |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SND1-IT1 | SND1 intronic transcript 1 |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| SREK1IP1 | SREK1-interacting protein 1 |
| ST5 | suppression of tumorigenicity 5 |
| STAC | SH3 and cysteine rich domain |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TBL3 | transducin (beta)-like 3 |
| TEX40 | testis expressed 40 |
| TMEM104 | transmembrane protein 104 |
| TMEM110 | transmembrane protein 110 |
| TMEM183A | transmembrane protein 183A |
| TMEM209 | transmembrane protein 209 |
| TMEM62 | transmembrane protein 62 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TNRC6B | trinucleotide repeat containing 6B |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TWF2 | twinfilin actin binding protein 2 |
| VWA9 | von Willebrand factor A domain containing 9 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZFP69B | ZFP69 zinc finger protein B |
| ZNF324 | zinc finger protein 324 |
| ZNF408 | zinc finger protein 408 |
| ZNF571 | zinc finger protein 571 |
| ZNF668 | zinc finger protein 668 |
| ZNF767P | zinc finger family member 767, pseudogene |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
