| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the doxepin-7415 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AHI1 | Abelson helper integration site 1 |
| AKAP17A | A kinase (PRKA) anchor protein 17A |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| BBS9 | Bardet-Biedl syndrome 9 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CAMK2B | calcium/calmodulin-dependent protein kinase II beta |
| CAMK2G | calcium/calmodulin-dependent protein kinase II gamma |
| CAPG | capping protein (actin filament), gelsolin-like |
| CCDC134 | coiled-coil domain containing 134 |
| CCNG2 | cyclin G2 |
| CEP162 | centrosomal protein 162kDa |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 |
| DIMT1 | DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae) |
| DUSP2 | dual specificity phosphatase 2 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| ELK4 | ELK4, ETS-domain protein (SRF accessory protein 1) |
| FADS3 | fatty acid desaturase 3 |
| FGFR1 | fibroblast growth factor receptor 1 |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 |
| GPR137 | G protein-coupled receptor 137 |
| HIPK3 | homeodomain interacting protein kinase 3 |
| HIST1H2BC | histone cluster 1, H2bc |
| IL4R | interleukin 4 receptor |
| IRF5 | interferon regulatory factor 5 |
| IRF6 | interferon regulatory factor 6 |
| KDM5A | lysine (K)-specific demethylase 5A |
| KIAA0485 | uncharacterized LOC57235 |
| KIF13B | kinesin family member 13B |
| KRT8 | keratin 8, type II |
| LAMC2 | laminin, gamma 2 |
| LIMK1 | LIM domain kinase 1 |
| LPCAT3 | lysophosphatidylcholine acyltransferase 3 |
| LRRC23 | leucine rich repeat containing 23 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MBD1 | methyl-CpG binding domain protein 1 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 |
| MEF2D | myocyte enhancer factor 2D |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MVD | mevalonate (diphospho) decarboxylase |
| MXD4 | MAX dimerization protein 4 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| N4BP3 | NEDD4 binding protein 3 |
| NAAA | N-acylethanolamine acid amidase |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NKX3-1 | NK3 homeobox 1 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| ORAI2 | ORAI calcium release-activated calcium modulator 2 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PLAGL1 | pleiomorphic adenoma gene-like 1 |
| PLIN2 | perilipin 2 |
| POFUT1 | protein O-fucosyltransferase 1 |
| POLL | polymerase (DNA directed), lambda |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| PPFIA3 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 |
| PRY | PTPN13-like, Y-linked |
| PXDC1 | PX domain containing 1 |
| RAB40B | RAB40B, member RAS oncogene family |
| RECQL5 | RecQ protein-like 5 |
| RIN1 | Ras and Rab interactor 1 |
| RNF39 | ring finger protein 39 |
| RSU1 | Ras suppressor protein 1 |
| RTN2 | reticulon 2 |
| RUFY3 | RUN and FYVE domain containing 3 |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SH2B1 | SH2B adaptor protein 1 |
| SIK2 | salt-inducible kinase 2 |
| SLC1A7 | solute carrier family 1 (glutamate transporter), member 7 |
| SNAI2 | snail family zinc finger 2 |
| SND1-IT1 | SND1 intronic transcript 1 |
| SPAM1 | sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) |
| SYMPK | symplekin |
| SYNGR1 | synaptogyrin 1 |
| TADA2A | transcriptional adaptor 2A |
| TAPBP | TAP binding protein (tapasin) |
| TRAIP | TRAF interacting protein |
| TRIM2 | tripartite motif containing 2 |
| TTC33 | tetratricopeptide repeat domain 33 |
| USP34 | ubiquitin specific peptidase 34 |
| VLDLR | very low density lipoprotein receptor |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| WWTR1 | WW domain containing transcription regulator 1 |
| YTHDC2 | YTH domain containing 2 |
| ZFAND6 | zinc finger, AN1-type domain 6 |
| ZMYM2 | zinc finger, MYM-type 2 |
| ZNF136 | zinc finger protein 136 |
| ZNF45 | zinc finger protein 45 |
| Symbol | Name |
|---|---|
| ABHD4 | abhydrolase domain containing 4 |
| ACO1 | aconitase 1, soluble |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ALPK1 | alpha-kinase 1 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| AP3M2 | adaptor-related protein complex 3, mu 2 subunit |
| APOO | apolipoprotein O |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) |
| ARL15 | ADP-ribosylation factor-like 15 |
| AXIN1 | axin 1 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| CLSPN | claspin |
| COQ9 | coenzyme Q9 |
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DDIT3 | DNA-damage-inducible transcript 3 |
| ECH1 | enoyl CoA hydratase 1, peroxisomal |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FKBP5 | FK506 binding protein 5 |
| FOSL1 | FOS-like antigen 1 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| FRAT1 | frequently rearranged in advanced T-cell lymphomas 1 |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| FUZ | fuzzy planar cell polarity protein |
| FZD4 | frizzled class receptor 4 |
| GAREM | GRB2 associated, regulator of MAPK1 |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GPR87 | G protein-coupled receptor 87 |
| HMBOX1 | homeobox containing 1 |
| HOXC10 | homeobox C10 |
| IRX4 | iroquois homeobox 4 |
| KLHL21 | kelch-like family member 21 |
| KRBOX4 | KRAB box domain containing 4 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 |
| LOC100272216 | uncharacterized LOC100272216 |
| LOC100287590 | uncharacterized LOC100287590 |
| LRRC37A2 | leucine rich repeat containing 37, member A2 |
| LYPD1 | LY6/PLAUR domain containing 1 |
| LZTFL1 | leucine zipper transcription factor-like 1 |
| MAGEH1 | melanoma antigen family H1 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MCOLN1 | mucolipin 1 |
| MEIS1 | Meis homeobox 1 |
| MICALL2 | MICAL-like 2 |
| MUM1 | melanoma associated antigen (mutated) 1 |
| MYO1E | myosin IE |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NRSN2 | neurensin 2 |
| NVL | nuclear VCP-like |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PER3 | period circadian clock 3 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PGPEP1 | pyroglutamyl-peptidase I |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| PMM1 | phosphomannomutase 1 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| RCOR3 | REST corepressor 3 |
| RNASEH2B | ribonuclease H2, subunit B |
| RNF123 | ring finger protein 123 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SLC37A1 | solute carrier family 37 (glucose-6-phosphate transporter), member 1 |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| SPATA7 | spermatogenesis associated 7 |
| STX17 | syntaxin 17 |
| TBC1D17 | TBC1 domain family, member 17 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) |
| TM7SF3 | transmembrane 7 superfamily member 3 |
| TRABD | TraB domain containing |
| TRIM25 | tripartite motif containing 25 |
| TSPAN1 | tetraspanin 1 |
| TUBA3C | tubulin, alpha 3c |
| TXLNG | taxilin gamma |
| TXNL4B | thioredoxin-like 4B |
| VPS11 | vacuolar protein sorting 11 homolog (S. cerevisiae) |
| WDR60 | WD repeat domain 60 |
| YEATS2 | YEATS domain containing 2 |
| YIPF1 | Yip1 domain family, member 1 |
| ZNF205 | zinc finger protein 205 |
| ZNF286A | zinc finger protein 286A |
| ZNF428 | zinc finger protein 428 |
| ZNF787 | zinc finger protein 787 |
| ZW10 | zw10 kinetochore protein |
