doxorubicin Gene Set

Dataset Phosphosite Textmining Biological Term Annotations
Category structural or functional annotations
Type biological term
Description An anthracycline antibiotic that has formula C27H29NO11. (Chemical Entities of Biological Interest Ontology, CHEBI_28748)
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Genes

57 proteins co-occuring with the biological term doxorubicin in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

Symbol Name
AATF apoptosis antagonizing transcription factor
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ADRBK1 adrenergic, beta, receptor kinase 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
ATM ATM serine/threonine kinase
ATR ATR serine/threonine kinase
BCL2 B-cell CLL/lymphoma 2
BIRC5 baculoviral IAP repeat containing 5
CDC25C cell division cycle 25C
CDK1 cyclin-dependent kinase 1
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
E2F1 E2F transcription factor 1
E2F3 E2F transcription factor 3
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
FOXO3 forkhead box O3
GJA1 gap junction protein, alpha 1, 43kDa
H2AFX H2A histone family, member X
HIST1H3A histone cluster 1, H3a
HSPB1 heat shock 27kDa protein 1
JUN jun proto-oncogene
KAT7 K(lysine) acetyltransferase 7
MAP2K4 mitogen-activated protein kinase kinase 4
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MLH1 mutL homolog 1
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NFE2L2 nuclear factor, erythroid 2-like 2
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PARN poly(A)-specific ribonuclease
PDPK1 3-phosphoinositide dependent protein kinase 1
PLK1 polo-like kinase 1
PLSCR3 phospholipid scramblase 3
PTEN phosphatase and tensin homolog
PTK2 protein tyrosine kinase 2
RAD9A RAD9 homolog A (S. pombe)
RALBP1 ralA binding protein 1
RB1 retinoblastoma 1
RPS6 ribosomal protein S6
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SMC1A structural maintenance of chromosomes 1A
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SSTR2 somatostatin receptor 2
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TOP2A topoisomerase (DNA) II alpha 170kDa
TP53 tumor protein p53
TP63 tumor protein p63
TRIM28 tripartite motif containing 28
TWIST1 twist family bHLH transcription factor 1