| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the doxycycline-5838 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
| ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 |
| ADGRF5 | adhesion G protein-coupled receptor F5 |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| ALDH1B1 | aldehyde dehydrogenase 1 family, member B1 |
| AMBRA1 | autophagy/beclin-1 regulator 1 |
| ARHGAP1 | Rho GTPase activating protein 1 |
| BRWD1 | bromodomain and WD repeat domain containing 1 |
| BTC | betacellulin |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CD86 | CD86 molecule |
| CDC25C | cell division cycle 25C |
| CES3 | carboxylesterase 3 |
| CHD7 | chromodomain helicase DNA binding protein 7 |
| DDX28 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DOCK9 | dedicator of cytokinesis 9 |
| DTX2P1-UPK3BP1-PMS2P11 | DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene |
| EGFR | epidermal growth factor receptor |
| EXTL3 | exostosin-like glycosyltransferase 3 |
| FSCN3 | fascin actin-bundling protein 3, testicular |
| FYB | FYN binding protein |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GHRH | growth hormone releasing hormone |
| GLB1L2 | galactosidase, beta 1-like 2 |
| GLP1R | glucagon-like peptide 1 receptor |
| GM2A | GM2 ganglioside activator |
| GTPBP4 | GTP binding protein 4 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IL1RN | interleukin 1 receptor antagonist |
| IL6 | interleukin 6 |
| INPP5B | inositol polyphosphate-5-phosphatase, 75kDa |
| INPP5K | inositol polyphosphate-5-phosphatase K |
| KCNJ9 | potassium channel, inwardly rectifying subfamily J, member 9 |
| KCNQ2 | potassium channel, voltage gated KQT-like subfamily Q, member 2 |
| KIAA1462 | KIAA1462 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LCK | LCK proto-oncogene, Src family tyrosine kinase |
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MORC1 | MORC family CW-type zinc finger 1 |
| MST1L | macrophage stimulating 1-like |
| MVP | major vault protein |
| NPY6R | neuropeptide Y receptor Y6 (pseudogene) |
| NUCB1 | nucleobindin 1 |
| ONECUT2 | one cut homeobox 2 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PLCH2 | phospholipase C, eta 2 |
| PLIN2 | perilipin 2 |
| PLXDC1 | plexin domain containing 1 |
| PPARD | peroxisome proliferator-activated receptor delta |
| PRF1 | perforin 1 (pore forming protein) |
| PRR7 | proline rich 7 (synaptic) |
| RAB11B | RAB11B, member RAS oncogene family |
| RAB3B | RAB3B, member RAS oncogene family |
| RGS7 | regulator of G-protein signaling 7 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) |
| RPL13 | ribosomal protein L13 |
| RUNX1 | runt-related transcription factor 1 |
| SCN3B | sodium channel, voltage gated, type III beta subunit |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit |
| SDC2 | syndecan 2 |
| SERPINI2 | serpin peptidase inhibitor, clade I (pancpin), member 2 |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SHMT1 | serine hydroxymethyltransferase 1 (soluble) |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 |
| SIRT3 | sirtuin 3 |
| SLC16A5 | solute carrier family 16 (monocarboxylate transporter), member 5 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| SSH3 | slingshot protein phosphatase 3 |
| STAC | SH3 and cysteine rich domain |
| STMN4 | stathmin-like 4 |
| STS | steroid sulfatase (microsomal), isozyme S |
| SYT17 | synaptotagmin XVII |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TBC1D30 | TBC1 domain family, member 30 |
| TEX40 | testis expressed 40 |
| TMEM132A | transmembrane protein 132A |
| TRIM23 | tripartite motif containing 23 |
| TRIM48 | tripartite motif containing 48 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TSPAN8 | tetraspanin 8 |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| XAF1 | XIAP associated factor 1 |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase |
| YIPF4 | Yip1 domain family, member 4 |
| YY1 | YY1 transcription factor |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZNF324 | zinc finger protein 324 |
| ZNF362 | zinc finger protein 362 |
| ZNF606 | zinc finger protein 606 |
| Symbol | Name |
|---|---|
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ANAPC2 | anaphase promoting complex subunit 2 |
| ANG | angiogenin, ribonuclease, RNase A family, 5 |
| ANKRD36 | ankyrin repeat domain 36 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| ARHGEF5 | Rho guanine nucleotide exchange factor (GEF) 5 |
| ARL14 | ADP-ribosylation factor-like 14 |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| BHLHB9 | basic helix-loop-helix domain containing, class B, 9 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CARD8 | caspase recruitment domain family, member 8 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CDKN2AIP | CDKN2A interacting protein |
| CIR1 | corepressor interacting with RBPJ, 1 |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| COBL | cordon-bleu WH2 repeat protein |
| COQ6 | coenzyme Q6 monooxygenase |
| CTSO | cathepsin O |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 |
| DCAF16 | DDB1 and CUL4 associated factor 16 |
| DET1 | de-etiolated homolog 1 (Arabidopsis) |
| DNAL4 | dynein, axonemal, light chain 4 |
| EDC3 | enhancer of mRNA decapping 3 |
| EFNA4 | ephrin-A4 |
| EGLN2 | egl-9 family hypoxia-inducible factor 2 |
| ELP3 | elongator acetyltransferase complex subunit 3 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| ERF | Ets2 repressor factor |
| FAM53B | family with sequence similarity 53, member B |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GMIP | GEM interacting protein |
| GRPR | gastrin-releasing peptide receptor |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HLA-J | major histocompatibility complex, class I, J (pseudogene) |
| IFT54 | intraflagellar transport 54 |
| IL17RB | interleukin 17 receptor B |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
| ITPKC | inositol-trisphosphate 3-kinase C |
| KIFC1 | kinesin family member C1 |
| KLF2 | Kruppel-like factor 2 |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MTG1 | mitochondrial ribosome-associated GTPase 1 |
| NARFL | nuclear prelamin A recognition factor-like |
| NCF2 | neutrophil cytosolic factor 2 |
| NCS1 | neuronal calcium sensor 1 |
| NOL12 | nucleolar protein 12 |
| NR2C2 | nuclear receptor subfamily 2, group C, member 2 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| ORC2 | origin recognition complex, subunit 2 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PGM3 | phosphoglucomutase 3 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PPP2R2D | protein phosphatase 2, regulatory subunit B, delta |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit |
| PRRC1 | proline-rich coiled-coil 1 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PTPN3 | protein tyrosine phosphatase, non-receptor type 3 |
| RNF25 | ring finger protein 25 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
| RPAP2 | RNA polymerase II associated protein 2 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SCAMP5 | secretory carrier membrane protein 5 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| STBD1 | starch binding domain 1 |
| STEAP4 | STEAP family member 4 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TKFC | triokinase/FMN cyclase |
| TMEM186 | transmembrane protein 186 |
| TMEM212 | transmembrane protein 212 |
| TMOD3 | tropomodulin 3 (ubiquitous) |
| TNFSF12 | tumor necrosis factor (ligand) superfamily, member 12 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TNRC6B | trinucleotide repeat containing 6B |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| TSPYL2 | TSPY-like 2 |
| UNKL | unkempt family zinc finger-like |
| WDR18 | WD repeat domain 18 |
| WDR76 | WD repeat domain 76 |
| YIPF5 | Yip1 domain family, member 5 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZBTB39 | zinc finger and BTB domain containing 39 |
| ZNF197 | zinc finger protein 197 |
| ZNF34 | zinc finger protein 34 |
| ZNF385D | zinc finger protein 385D |
| ZNF426 | zinc finger protein 426 |
| ZNF8 | zinc finger protein 8 |
| ZNF862 | zinc finger protein 862 |
