doxylamine-1893 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the doxylamine-1893 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
APOE apolipoprotein E
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15
ATXN2 ataxin 2
BCL2L14 BCL2-like 14 (apoptosis facilitator)
BMP1 bone morphogenetic protein 1
C19ORF40 chromosome 19 open reading frame 40
CALD1 caldesmon 1
CBFB core-binding factor, beta subunit
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CEND1 cell cycle exit and neuronal differentiation 1
CENPT centromere protein T
CETN1 centrin, EF-hand protein, 1
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CRCP CGRP receptor component
CREB1 cAMP responsive element binding protein 1
CRMP1 collapsin response mediator protein 1
DEK DEK proto-oncogene
DENND3 DENN/MADD domain containing 3
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAAF2 dynein, axonemal, assembly factor 2
ERAP1 endoplasmic reticulum aminopeptidase 1
ETAA1 Ewing tumor-associated antigen 1
EVPL envoplakin
FAM63A family with sequence similarity 63, member A
FBXW12 F-box and WD repeat domain containing 12
FGFR1 fibroblast growth factor receptor 1
GATA2 GATA binding protein 2
GCDH glutaryl-CoA dehydrogenase
GJD2 gap junction protein, delta 2, 36kDa
GLE1 GLE1 RNA export mediator
GTPBP1 GTP binding protein 1
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HMGN5 high mobility group nucleosome binding domain 5
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IPP intracisternal A particle-promoted polypeptide
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIAA1549L KIAA1549-like
KLHL24 kelch-like family member 24
KPTN kaptin (actin binding protein)
LECT1 leukocyte cell derived chemotaxin 1
LIAS lipoic acid synthetase
LIMK2 LIM domain kinase 2
LIMS2 LIM and senescent cell antigen-like domains 2
MCC mutated in colorectal cancers
MED13L mediator complex subunit 13-like
MFSD11 major facilitator superfamily domain containing 11
MPHOSPH9 M-phase phosphoprotein 9
MST1 macrophage stimulating 1
MYL10 myosin, light chain 10, regulatory
MZT2B mitotic spindle organizing protein 2B
NAP1L1 nucleosome assembly protein 1-like 1
NKIRAS2 NFKB inhibitor interacting Ras-like 2
NPEPL1 aminopeptidase-like 1
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
NUP214 nucleoporin 214kDa
ORAI3 ORAI calcium release-activated calcium modulator 3
PCM1 pericentriolar material 1
PDE3B phosphodiesterase 3B, cGMP-inhibited
PLK4 polo-like kinase 4
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PRRC2B proline-rich coiled-coil 2B
PTP4A1 protein tyrosine phosphatase type IVA, member 1
REPS2 RALBP1 associated Eps domain containing 2
RGS19 regulator of G-protein signaling 19
RHOQ ras homolog family member Q
RIOK3 RIO kinase 3
RNF144A ring finger protein 144A
RNGTT RNA guanylyltransferase and 5'-phosphatase
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila)
RPL14 ribosomal protein L14
SAP18 Sin3A-associated protein, 18kDa
SIPA1L3 signal-induced proliferation-associated 1 like 3
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SPN sialophorin
STX1A syntaxin 1A (brain)
SVIL supervillin
TBCD tubulin folding cofactor D
THRB thyroid hormone receptor, beta
TMCC2 transmembrane and coiled-coil domain family 2
TMEM156 transmembrane protein 156
TMPRSS5 transmembrane protease, serine 5
TMSB4Y thymosin beta 4, Y-linked
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TSPAN15 tetraspanin 15
U2SURP U2 snRNP-associated SURP domain containing
USP34 ubiquitin specific peptidase 34
WDR19 WD repeat domain 19
WEE1 WEE1 G2 checkpoint kinase
WIZ widely interspaced zinc finger motifs
WWP1 WW domain containing E3 ubiquitin protein ligase 1
ZC3H7B zinc finger CCCH-type containing 7B
ZNF107 zinc finger protein 107
ZNF710 zinc finger protein 710

decreased expression

Symbol Name
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3
ACTG2 actin, gamma 2, smooth muscle, enteric
AIDA axin interactor, dorsalization associated
APLP1 amyloid beta (A4) precursor-like protein 1
ATG9A autophagy related 9A
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide
BSG basigin (Ok blood group)
C12ORF29 chromosome 12 open reading frame 29
C1ORF123 chromosome 1 open reading frame 123
C21ORF59 chromosome 21 open reading frame 59
CAPG capping protein (actin filament), gelsolin-like
CARHSP1 calcium regulated heat stable protein 1, 24kDa
CCDC53 coiled-coil domain containing 53
CCNT1 cyclin T1
CEP85 centrosomal protein 85kDa
COASY CoA synthase
COMMD10 COMM domain containing 10
CRIP2 cysteine-rich protein 2
CYB5R4 cytochrome b5 reductase 4
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DENND4B DENN/MADD domain containing 4B
DESI1 desumoylating isopeptidase 1
DMBT1 deleted in malignant brain tumors 1
DMTN dematin actin binding protein
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha)
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ERCC2 excision repair cross-complementation group 2
ERI3 ERI1 exoribonuclease family member 3
EVL Enah/Vasp-like
EXOC5 exocyst complex component 5
FAM188A family with sequence similarity 188, member A
FMO4 flavin containing monooxygenase 4
GALR3 galanin receptor 3
GBAP1 glucosidase, beta, acid pseudogene 1
GLI3 GLI family zinc finger 3
GLOD4 glyoxalase domain containing 4
GSTZ1 glutathione S-transferase zeta 1
GTPBP2 GTP binding protein 2
HACD2 3-hydroxyacyl-CoA dehydratase 2
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2
HIST1H2BH histone cluster 1, H2bh
HMGB3P1 high mobility group box 3 pseudogene 1
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
KRT34 keratin 34, type I
KRT86 keratin 86, type II
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAPK3 mitogen-activated protein kinase 3
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MPDU1 mannose-P-dolichol utilization defect 1
MPV17 MpV17 mitochondrial inner membrane protein
MRPL35 mitochondrial ribosomal protein L35
MRPL40 mitochondrial ribosomal protein L40
MT1HL1 metallothionein 1H-like 1
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
OSGEP O-sialoglycoprotein endopeptidase
PAAF1 proteasomal ATPase-associated factor 1
PHB prohibitin
PHKA1 phosphorylase kinase, alpha 1 (muscle)
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PLCD1 phospholipase C, delta 1
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PLEKHO2 pleckstrin homology domain containing, family O member 2
PLTP phospholipid transfer protein
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PPP4C protein phosphatase 4, catalytic subunit
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
PUS1 pseudouridylate synthase 1
PYCRL pyrroline-5-carboxylate reductase-like
RAB17 RAB17, member RAS oncogene family
RAB25 RAB25, member RAS oncogene family
RBM7 RNA binding motif protein 7
RBMS3 RNA binding motif, single stranded interacting protein 3
RIC8A RIC8 guanine nucleotide exchange factor A
RPP30 ribonuclease P/MRP 30kDa subunit
RUVBL1 RuvB-like AAA ATPase 1
RUVBL2 RuvB-like AAA ATPase 2
SAP30L SAP30-like
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC4A2 solute carrier family 4 (anion exchanger), member 2
STK25 serine/threonine kinase 25
STX10 syntaxin 10
SURF2 surfeit 2
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast)
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast)
TMEM110 transmembrane protein 110
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
TTC13 tetratricopeptide repeat domain 13
UBAC1 UBA domain containing 1
UNC13B unc-13 homolog B (C. elegans)
VAT1 vesicle amine transport 1
WDR13 WD repeat domain 13
ZFAND3 zinc finger, AN1-type domain 3