doxylamine-1973 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the doxylamine-1973 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AACS acetoacetyl-CoA synthetase
AAK1 AP2 associated kinase 1
ABHD3 abhydrolase domain containing 3
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
ANKRD12 ankyrin repeat domain 12
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASB8 ankyrin repeat and SOCS box containing 8
ASPH aspartate beta-hydroxylase
AVL9 AVL9 homolog (S. cerevisiase)
B3GNT1
BBIP1 BBSome interacting protein 1
BBS1 Bardet-Biedl syndrome 1
BBX bobby sox homolog (Drosophila)
BEX1 brain expressed, X-linked 1
CASP7 caspase 7, apoptosis-related cysteine peptidase
CD164 CD164 molecule, sialomucin
CD2AP CD2-associated protein
CETN1 centrin, EF-hand protein, 1
CHD9 chromodomain helicase DNA binding protein 9
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
COG5 component of oligomeric golgi complex 5
CYB561 cytochrome b561
DEAF1 DEAF1 transcription factor
DMBT1 deleted in malignant brain tumors 1
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DSN1 DSN1, MIS12 kinetochore complex component
EFR3A EFR3 homolog A (S. cerevisiae)
EIF4E eukaryotic translation initiation factor 4E
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FAM106A family with sequence similarity 106, member A
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FN1 fibronectin 1
FTH1 ferritin, heavy polypeptide 1
GIN1 gypsy retrotransposon integrase 1
HIGD2A HIG1 hypoxia inducible domain family, member 2A
HIRA histone cell cycle regulator
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
IDS iduronate 2-sulfatase
IL1RAP interleukin 1 receptor accessory protein
IRAK3 interleukin-1 receptor-associated kinase 3
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KDM2A lysine (K)-specific demethylase 2A
KIFC1 kinesin family member C1
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LIN7C lin-7 homolog C (C. elegans)
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAGED2 melanoma antigen family D2
MAGT1 magnesium transporter 1
MAN1A1 mannosidase, alpha, class 1A, member 1
MGAM maltase-glucoamylase
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MNS1 meiosis-specific nuclear structural 1
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MTMR2 myotubularin related protein 2
MYL10 myosin, light chain 10, regulatory
NEK7 NIMA-related kinase 7
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NIPAL2 NIPA-like domain containing 2
PCDH7 protocadherin 7
PEX13 peroxisomal biogenesis factor 13
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLCD1 phospholipase C, delta 1
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PPP1R7 protein phosphatase 1, regulatory subunit 7
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PRKRIR protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
RAB7A RAB7A, member RAS oncogene family
RABGAP1L RAB GTPase activating protein 1-like
RABGGTB Rab geranylgeranyltransferase, beta subunit
RAD23B RAD23 homolog B (S. cerevisiae)
RNF121 ring finger protein 121
SAT1 spermidine/spermine N1-acetyltransferase 1
SDHAF3 succinate dehydrogenase complex assembly factor 3
SKAP2 src kinase associated phosphoprotein 2
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
STAT1 signal transducer and activator of transcription 1, 91kDa
SUGP1 SURP and G patch domain containing 1
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)
TFG TRK-fused gene
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TRD T cell receptor delta locus
TRHDE thyrotropin-releasing hormone degrading enzyme
TSFM Ts translation elongation factor, mitochondrial
TSPYL2 TSPY-like 2
UBXN2B UBX domain protein 2B
USP46 ubiquitin specific peptidase 46
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
ZNF197 zinc finger protein 197
ZNF302 zinc finger protein 302
ZNF609 zinc finger protein 609
ZNF696 zinc finger protein 696
ZNF83 zinc finger protein 83

decreased expression

Symbol Name
ACO1 aconitase 1, soluble
ADAM23 ADAM metallopeptidase domain 23
ANAPC2 anaphase promoting complex subunit 2
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ANXA6 annexin A6
AP1G1 adaptor-related protein complex 1, gamma 1 subunit
APH1B APH1B gamma secretase subunit
APOBR apolipoprotein B receptor
ATXN2 ataxin 2
BCL7C B-cell CLL/lymphoma 7C
BTNL3 butyrophilin-like 3
C1ORF109 chromosome 1 open reading frame 109
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CEND1 cell cycle exit and neuronal differentiation 1
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase
COPS7B COP9 signalosome subunit 7B
CORO7 coronin 7
CRYBB2P1 crystallin, beta B2 pseudogene 1
DBF4B DBF4 zinc finger B
DCAF16 DDB1 and CUL4 associated factor 16
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DOK3 docking protein 3
DPH2 DPH2 homolog (S. cerevisiae)
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha)
ERCC2 excision repair cross-complementation group 2
FANCE Fanconi anemia, complementation group E
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GMEB1 glucocorticoid modulatory element binding protein 1
GOLM1 golgi membrane protein 1
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HARS histidyl-tRNA synthetase
IFI30 interferon, gamma-inducible protein 30
IFITM3 interferon induced transmembrane protein 3
INTS9 integrator complex subunit 9
IRF1 interferon regulatory factor 1
ITFG1 integrin alpha FG-GAP repeat containing 1
ITGA10 integrin, alpha 10
JUNB jun B proto-oncogene
KCTD15 potassium channel tetramerization domain containing 15
KRI1 KRI1 homolog (S. cerevisiae)
KRT38 keratin 38, type I
LRRC37A3 leucine rich repeat containing 37, member A3
LRRK1 leucine-rich repeat kinase 1
LTB lymphotoxin beta (TNF superfamily, member 3)
MAD2L1BP MAD2L1 binding protein
MAPK10 mitogen-activated protein kinase 10
MFSD11 major facilitator superfamily domain containing 11
MON1B MON1 secretory trafficking family member B
MT1HL1 metallothionein 1H-like 1
MXRA8 matrix-remodelling associated 8
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OXCT1 3-oxoacid CoA transferase 1
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
PCDHGB5 protocadherin gamma subfamily B, 5
PCNXL4 pecanex-like 4 (Drosophila)
PCSK7 proprotein convertase subtilisin/kexin type 7
PDCD5 programmed cell death 5
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PISD phosphatidylserine decarboxylase
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PTOV1 prostate tumor overexpressed 1
PUS1 pseudouridylate synthase 1
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
RRP1 ribosomal RNA processing 1
SERTAD3 SERTA domain containing 3
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SH3GL1 SH3-domain GRB2-like 1
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMYD5 SMYD family member 5
SND1 staphylococcal nuclease and tudor domain containing 1
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STX4 syntaxin 4
TAC3 tachykinin 3
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative)
TM7SF2 transmembrane 7 superfamily member 2
TMED1 transmembrane emp24 protein transport domain containing 1
TRIM26 tripartite motif containing 26
TSEN2 TSEN2 tRNA splicing endonuclease subunit
TWF2 twinfilin actin binding protein 2
UBA5 ubiquitin-like modifier activating enzyme 5
USB1 U6 snRNA biogenesis 1
WNT10B wingless-type MMTV integration site family, member 10B
XPO4 exportin 4
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial
ZDHHC18 zinc finger, DHHC-type containing 18
ZDHHC6 zinc finger, DHHC-type containing 6
ZDHHC7 zinc finger, DHHC-type containing 7
ZNF282 zinc finger protein 282
ZNF8 zinc finger protein 8