| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the doxylamine-4235 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ACACB | acetyl-CoA carboxylase beta |
| ACVR1B | activin A receptor, type IB |
| ADH7 | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide |
| AGBL3 | ATP/GTP binding protein-like 3 |
| AK1 | adenylate kinase 1 |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| B9D1 | B9 protein domain 1 |
| BCL2 | B-cell CLL/lymphoma 2 |
| BTBD18 | BTB (POZ) domain containing 18 |
| BUD31 | BUD31 homolog (S. cerevisiae) |
| C9ORF156 | chromosome 9 open reading frame 156 |
| CASR | calcium-sensing receptor |
| CCDC177 | coiled-coil domain containing 177 |
| CCND2 | cyclin D2 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CD48 | CD48 molecule |
| CEMP1 | cementum protein 1 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLSTN3 | calsyntenin 3 |
| CNTFR | ciliary neurotrophic factor receptor |
| COL1A2 | collagen, type I, alpha 2 |
| CRLF2 | cytokine receptor-like factor 2 |
| DMP1 | dentin matrix acidic phosphoprotein 1 |
| DPF3 | D4, zinc and double PHD fingers, family 3 |
| EFR3B | EFR3 homolog B (S. cerevisiae) |
| EXOSC2 | exosome component 2 |
| FAM65B | family with sequence similarity 65, member B |
| FGF18 | fibroblast growth factor 18 |
| FGF22 | fibroblast growth factor 22 |
| GAB1 | GRB2-associated binding protein 1 |
| GFI1 | growth factor independent 1 transcription repressor |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPR21 | G protein-coupled receptor 21 |
| HIPK3 | homeodomain interacting protein kinase 3 |
| HLA-F | major histocompatibility complex, class I, F |
| HPX | hemopexin |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| IL16 | interleukin 16 |
| IL21R | interleukin 21 receptor |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
| KLF4 | Kruppel-like factor 4 (gut) |
| KLK2 | kallikrein-related peptidase 2 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LOX | lysyl oxidase |
| LRRC17 | leucine rich repeat containing 17 |
| LRRC2 | leucine rich repeat containing 2 |
| MCF2L | MCF.2 cell line derived transforming sequence-like |
| MST1 | macrophage stimulating 1 |
| N4BP1 | NEDD4 binding protein 1 |
| NEU3 | sialidase 3 (membrane sialidase) |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NPR1 | natriuretic peptide receptor 1 |
| NPY2R | neuropeptide Y receptor Y2 |
| NR1H4 | nuclear receptor subfamily 1, group H, member 4 |
| NRCAM | neuronal cell adhesion molecule |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
| OAZ3 | ornithine decarboxylase antizyme 3 |
| OCM2 | oncomodulin 2 |
| PAOX | polyamine oxidase (exo-N4-amino) |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited |
| PDLIM4 | PDZ and LIM domain 4 |
| PLCL2 | phospholipase C-like 2 |
| PLEKHG3 | pleckstrin homology domain containing, family G (with RhoGef domain) member 3 |
| POU2F2 | POU class 2 homeobox 2 |
| PTPN22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) |
| PTPRR | protein tyrosine phosphatase, receptor type, R |
| RAD23B | RAD23 homolog B (S. cerevisiae) |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RGS5 | regulator of G-protein signaling 5 |
| RUNX1 | runt-related transcription factor 1 |
| S100A8 | S100 calcium binding protein A8 |
| SLC12A5 | solute carrier family 12 (potassium/chloride transporter), member 5 |
| SLC13A1 | solute carrier family 13 (sodium/sulfate symporter), member 1 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 |
| SPOCK3 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 |
| SPON1 | spondin 1, extracellular matrix protein |
| SPTB | spectrin, beta, erythrocytic |
| SSTR4 | somatostatin receptor 4 |
| STON1 | stonin 1 |
| SUGP1 | SURP and G patch domain containing 1 |
| TFCP2L1 | transcription factor CP2-like 1 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 |
| VAX2 | ventral anterior homeobox 2 |
| VNN2 | vanin 2 |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) |
| WDR62 | WD repeat domain 62 |
| ZNF141 | zinc finger protein 141 |
| ZNF219 | zinc finger protein 219 |
| ZNF268 | zinc finger protein 268 |
| Symbol | Name |
|---|---|
| ADAM2 | ADAM metallopeptidase domain 2 |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| AK5 | adenylate kinase 5 |
| ALDH1B1 | aldehyde dehydrogenase 1 family, member B1 |
| ANKRD36 | ankyrin repeat domain 36 |
| ARRB2 | arrestin, beta 2 |
| AXIN1 | axin 1 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| C14ORF105 | chromosome 14 open reading frame 105 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C4ORF19 | chromosome 4 open reading frame 19 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CAPN15 | calpain 15 |
| CBX8 | chromobox homolog 8 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CD68 | CD68 molecule |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) |
| CES3 | carboxylesterase 3 |
| CFAP45 | cilia and flagella associated protein 45 |
| CHMP6 | charged multivesicular body protein 6 |
| CXCR2 | chemokine (C-X-C motif) receptor 2 |
| CXORF21 | chromosome X open reading frame 21 |
| DOK5 | docking protein 5 |
| ERI3 | ERI1 exoribonuclease family member 3 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FAM222B | family with sequence similarity 222, member B |
| FBRS | fibrosin |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FBXO2 | F-box protein 2 |
| FKBP5 | FK506 binding protein 5 |
| FLT4 | fms-related tyrosine kinase 4 |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GALK1 | galactokinase 1 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GRINA | glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) |
| GRM4 | glutamate receptor, metabotropic 4 |
| HIST1H3A | histone cluster 1, H3a |
| HIST1H3G | histone cluster 1, H3g |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HOXC5 | homeobox C5 |
| IFNA17 | interferon, alpha 17 |
| IFT54 | intraflagellar transport 54 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KANSL3 | KAT8 regulatory NSL complex subunit 3 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KLF13 | Kruppel-like factor 13 |
| LMCD1 | LIM and cysteine-rich domains 1 |
| LRP5 | low density lipoprotein receptor-related protein 5 |
| LY6E | lymphocyte antigen 6 complex, locus E |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MYL9 | myosin, light chain 9, regulatory |
| MYO1F | myosin IF |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NPFFR1 | neuropeptide FF receptor 1 |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| P3H1 | prolyl 3-hydroxylase 1 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PARD6A | par-6 family cell polarity regulator alpha |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PLBD1 | phospholipase B domain containing 1 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PRF1 | perforin 1 (pore forming protein) |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRM2 | protamine 2 |
| PRSS53 | protease, serine, 53 |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| PXMP4 | peroxisomal membrane protein 4, 24kDa |
| RAB3A | RAB3A, member RAS oncogene family |
| RABEP1 | rabaptin, RAB GTPase binding effector protein 1 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SCARA3 | scavenger receptor class A, member 3 |
| SCEL | sciellin |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SOD3 | superoxide dismutase 3, extracellular |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SSBP3 | single stranded DNA binding protein 3 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TBC1D17 | TBC1 domain family, member 17 |
| TEX15 | testis expressed 15 |
| TLN1 | talin 1 |
| TRAC | T cell receptor alpha constant |
| TRIM25 | tripartite motif containing 25 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| TUBA3C | tubulin, alpha 3c |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| ZFP30 | ZFP30 zinc finger protein |
| ZNF140 | zinc finger protein 140 |
