| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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195 genes differentially expressed following the doxylamine-4819 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTN2 | actinin, alpha 2 |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| AMPD1 | adenosine monophosphate deaminase 1 |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| ATXN2L | ataxin 2-like |
| BGN | biglycan |
| BIRC7 | baculoviral IAP repeat containing 7 |
| BLZF1 | basic leucine zipper nuclear factor 1 |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| C6ORF62 | chromosome 6 open reading frame 62 |
| C8ORF44 | chromosome 8 open reading frame 44 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) |
| CAV2 | caveolin 2 |
| CCDC71 | coiled-coil domain containing 71 |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CDK18 | cyclin-dependent kinase 18 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CEP41 | centrosomal protein 41kDa |
| CES3 | carboxylesterase 3 |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CPB2 | carboxypeptidase B2 (plasma) |
| CPD | carboxypeptidase D |
| CT62 | cancer/testis antigen 62 |
| CTNS | cystinosin, lysosomal cystine transporter |
| CTSF | cathepsin F |
| CTSZ | cathepsin Z |
| DDR1-AS1 | DDR1 antisense RNA 1 (head to head) |
| EFNA3 | ephrin-A3 |
| EGR1 | early growth response 1 |
| ELAC1 | elaC ribonuclease Z 1 |
| FAS | Fas cell surface death receptor |
| FHL1 | four and a half LIM domains 1 |
| FRMD4B | FERM domain containing 4B |
| GAS7 | growth arrest-specific 7 |
| GGA3 | golgi-associated, gamma adaptin ear containing, ARF binding protein 3 |
| GLIPR1 | GLI pathogenesis-related 1 |
| GP6 | glycoprotein VI (platelet) |
| GPATCH2L | G patch domain containing 2-like |
| GRAMD1C | GRAM domain containing 1C |
| H2AFJ | H2A histone family, member J |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HEXIM1 | hexamethylene bis-acetamide inducible 1 |
| HIC2 | hypermethylated in cancer 2 |
| HLF | hepatic leukemia factor |
| HOXB2 | homeobox B2 |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IFT27 | intraflagellar transport 27 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon |
| ISG20L2 | interferon stimulated exonuclease gene 20kDa-like 2 |
| ITGA6 | integrin, alpha 6 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KCNQ2 | potassium channel, voltage gated KQT-like subfamily Q, member 2 |
| KRT19P2 | keratin 19 pseudogene 2 |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MAPK7 | mitogen-activated protein kinase 7 |
| MASP2 | mannan-binding lectin serine peptidase 2 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| METTL7A | methyltransferase like 7A |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs |
| MMP3 | matrix metallopeptidase 3 |
| NEK1 | NIMA-related kinase 1 |
| NOS1 | nitric oxide synthase 1 (neuronal) |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| OSGIN2 | oxidative stress induced growth inhibitor family member 2 |
| PARVA | parvin, alpha |
| PCNX | pecanex homolog (Drosophila) |
| PDE10A | phosphodiesterase 10A |
| PLCL2 | phospholipase C-like 2 |
| PODNL1 | podocan-like 1 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A |
| PQLC2 | PQ loop repeat containing 2 |
| PRMT2IP | PRMT2 interacting protein |
| PVRL3 | poliovirus receptor-related 3 |
| QSER1 | glutamine and serine rich 1 |
| RABGAP1 | RAB GTPase activating protein 1 |
| RASIP1 | Ras interacting protein 1 |
| RND1 | Rho family GTPase 1 |
| RRAGB | Ras-related GTP binding B |
| RRAGD | Ras-related GTP binding D |
| SMAD5 | SMAD family member 5 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| STIM1 | stromal interaction molecule 1 |
| SUGP1 | SURP and G patch domain containing 1 |
| TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) |
| TBC1D2 | TBC1 domain family, member 2 |
| TBX5 | T-box 5 |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TLDC1 | TBC/LysM-associated domain containing 1 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TRD | T cell receptor delta locus |
| TSC22D4 | TSC22 domain family, member 4 |
| UPK1A | uroplakin 1A |
| XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 |
| Symbol | Name |
|---|---|
| AARSD1 | alanyl-tRNA synthetase domain containing 1 |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATXN2 | ataxin 2 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BCAS1 | breast carcinoma amplified sequence 1 |
| BMP4 | bone morphogenetic protein 4 |
| BPGM | 2,3-bisphosphoglycerate mutase |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C2ORF44 | chromosome 2 open reading frame 44 |
| CAPN5 | calpain 5 |
| CCDC85C | coiled-coil domain containing 85C |
| CCDC94 | coiled-coil domain containing 94 |
| CDK3 | cyclin-dependent kinase 3 |
| CEP85 | centrosomal protein 85kDa |
| CFAP44 | cilia and flagella associated protein 44 |
| CHCHD3 | coiled-coil-helix-coiled-coil-helix domain containing 3 |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CORO7 | coronin 7 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CUL9 | cullin 9 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| EGFL7 | EGF-like-domain, multiple 7 |
| FADS2 | fatty acid desaturase 2 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| FLJ21369 | uncharacterized protein FLJ21369 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GALK1 | galactokinase 1 |
| GCHFR | GTP cyclohydrolase I feedback regulator |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GPKOW | G patch domain and KOW motifs |
| GPR87 | G protein-coupled receptor 87 |
| GPX2 | glutathione peroxidase 2 |
| GRB7 | growth factor receptor-bound protein 7 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HIST1H2BI | histone cluster 1, H2bi |
| IPO13 | importin 13 |
| JMJD4 | jumonji domain containing 4 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KIAA0125 | KIAA0125 |
| KIAA0556 | KIAA0556 |
| KLF13 | Kruppel-like factor 13 |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LIG1 | ligase I, DNA, ATP-dependent |
| LIN37 | lin-37 DREAM MuvB core complex component |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MB | myoglobin |
| MFSD10 | major facilitator superfamily domain containing 10 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
| MOSPD3 | motile sperm domain containing 3 |
| MPDU1 | mannose-P-dolichol utilization defect 1 |
| MYO1D | myosin ID |
| NIPAL2 | NIPA-like domain containing 2 |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 |
| ODF2 | outer dense fiber of sperm tails 2 |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PES1 | pescadillo ribosomal biogenesis factor 1 |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta |
| PLA2G3 | phospholipase A2, group III |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PPP2R1A | protein phosphatase 2, regulatory subunit A, alpha |
| RAB3A | RAB3A, member RAS oncogene family |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RBM23 | RNA binding motif protein 23 |
| RRP1 | ribosomal RNA processing 1 |
| S100A6 | S100 calcium binding protein A6 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| SREK1IP1 | SREK1-interacting protein 1 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
| TCTN1 | tectonic family member 1 |
| TH | tyrosine hydroxylase |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) |
| TMEM57 | transmembrane protein 57 |
| TMEM8A | transmembrane protein 8A |
| TSPO | translocator protein (18kDa) |
| TUBA3C | tubulin, alpha 3c |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| UPP1 | uridine phosphorylase 1 |
| USB1 | U6 snRNA biogenesis 1 |
| USP18 | ubiquitin specific peptidase 18 |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| WDR91 | WD repeat domain 91 |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZNF747 | zinc finger protein 747 |
| ZNF804A | zinc finger protein 804A |