doxylamine-4819 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the doxylamine-4819 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTN2 actinin, alpha 2
AGMAT agmatine ureohydrolase (agmatinase)
AMPD1 adenosine monophosphate deaminase 1
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
ATXN2L ataxin 2-like
BGN biglycan
BIRC7 baculoviral IAP repeat containing 7
BLZF1 basic leucine zipper nuclear factor 1
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C6ORF62 chromosome 6 open reading frame 62
C8ORF44 chromosome 8 open reading frame 44
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CAV2 caveolin 2
CCDC71 coiled-coil domain containing 71
CD79B CD79b molecule, immunoglobulin-associated beta
CDK18 cyclin-dependent kinase 18
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEP41 centrosomal protein 41kDa
CES3 carboxylesterase 3
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CPB2 carboxypeptidase B2 (plasma)
CPD carboxypeptidase D
CT62 cancer/testis antigen 62
CTNS cystinosin, lysosomal cystine transporter
CTSF cathepsin F
CTSZ cathepsin Z
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
EFNA3 ephrin-A3
EGR1 early growth response 1
ELAC1 elaC ribonuclease Z 1
FAS Fas cell surface death receptor
FHL1 four and a half LIM domains 1
FRMD4B FERM domain containing 4B
GAS7 growth arrest-specific 7
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GLIPR1 GLI pathogenesis-related 1
GP6 glycoprotein VI (platelet)
GPATCH2L G patch domain containing 2-like
GRAMD1C GRAM domain containing 1C
H2AFJ H2A histone family, member J
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HEXIM1 hexamethylene bis-acetamide inducible 1
HIC2 hypermethylated in cancer 2
HLF hepatic leukemia factor
HOXB2 homeobox B2
ICA1 islet cell autoantigen 1, 69kDa
IFT27 intraflagellar transport 27
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2
ITGA6 integrin, alpha 6
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2
KRT19P2 keratin 19 pseudogene 2
L3MBTL1 l(3)mbt-like 1 (Drosophila)
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAPK7 mitogen-activated protein kinase 7
MASP2 mannan-binding lectin serine peptidase 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
METTL7A methyltransferase like 7A
MKLN1 muskelin 1, intracellular mediator containing kelch motifs
MMP3 matrix metallopeptidase 3
NEK1 NIMA-related kinase 1
NOS1 nitric oxide synthase 1 (neuronal)
NT5M 5',3'-nucleotidase, mitochondrial
OSGIN2 oxidative stress induced growth inhibitor family member 2
PARVA parvin, alpha
PCNX pecanex homolog (Drosophila)
PDE10A phosphodiesterase 10A
PLCL2 phospholipase C-like 2
PODNL1 podocan-like 1
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PQLC2 PQ loop repeat containing 2
PRMT2IP PRMT2 interacting protein
PVRL3 poliovirus receptor-related 3
QSER1 glutamine and serine rich 1
RABGAP1 RAB GTPase activating protein 1
RASIP1 Ras interacting protein 1
RND1 Rho family GTPase 1
RRAGB Ras-related GTP binding B
RRAGD Ras-related GTP binding D
SMAD5 SMAD family member 5
SMG6 SMG6 nonsense mediated mRNA decay factor
SPDEF SAM pointed domain containing ETS transcription factor
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
STIM1 stromal interaction molecule 1
SUGP1 SURP and G patch domain containing 1
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TBC1D2 TBC1 domain family, member 2
TBX5 T-box 5
TCP11L1 t-complex 11, testis-specific-like 1
TLDC1 TBC/LysM-associated domain containing 1
TM4SF1 transmembrane 4 L six family member 1
TRD T cell receptor delta locus
TSC22D4 TSC22 domain family, member 4
UPK1A uroplakin 1A
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4

decreased expression

Symbol Name
AARSD1 alanyl-tRNA synthetase domain containing 1
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATXN2 ataxin 2
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BCAS1 breast carcinoma amplified sequence 1
BMP4 bone morphogenetic protein 4
BPGM 2,3-bisphosphoglycerate mutase
C11ORF63 chromosome 11 open reading frame 63
C11ORF80 chromosome 11 open reading frame 80
C2ORF44 chromosome 2 open reading frame 44
CAPN5 calpain 5
CCDC85C coiled-coil domain containing 85C
CCDC94 coiled-coil domain containing 94
CDK3 cyclin-dependent kinase 3
CEP85 centrosomal protein 85kDa
CFAP44 cilia and flagella associated protein 44
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3
COPZ2 coatomer protein complex, subunit zeta 2
CORO7 coronin 7
CPPED1 calcineurin-like phosphoesterase domain containing 1
CUL9 cullin 9
DDIT3 DNA-damage-inducible transcript 3
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
EGFL7 EGF-like-domain, multiple 7
FADS2 fatty acid desaturase 2
FKBP1B FK506 binding protein 1B, 12.6 kDa
FLJ21369 uncharacterized protein FLJ21369
FSTL3 follistatin-like 3 (secreted glycoprotein)
GALK1 galactokinase 1
GCHFR GTP cyclohydrolase I feedback regulator
GMEB1 glucocorticoid modulatory element binding protein 1
GPKOW G patch domain and KOW motifs
GPR87 G protein-coupled receptor 87
GPX2 glutathione peroxidase 2
GRB7 growth factor receptor-bound protein 7
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HIST1H2BI histone cluster 1, H2bi
IPO13 importin 13
JMJD4 jumonji domain containing 4
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIAA0125 KIAA0125
KIAA0556 KIAA0556
KLF13 Kruppel-like factor 13
KRI1 KRI1 homolog (S. cerevisiae)
LARP6 La ribonucleoprotein domain family, member 6
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LIG1 ligase I, DNA, ATP-dependent
LIN37 lin-37 DREAM MuvB core complex component
LRP3 low density lipoprotein receptor-related protein 3
LY6D lymphocyte antigen 6 complex, locus D
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MB myoglobin
MFSD10 major facilitator superfamily domain containing 10
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MOSPD3 motile sperm domain containing 3
MPDU1 mannose-P-dolichol utilization defect 1
MYO1D myosin ID
NIPAL2 NIPA-like domain containing 2
NKAIN1 Na+/K+ transporting ATPase interacting 1
NR1H2 nuclear receptor subfamily 1, group H, member 2
ODF2 outer dense fiber of sperm tails 2
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PES1 pescadillo ribosomal biogenesis factor 1
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PLA2G3 phospholipase A2, group III
PLEKHA6 pleckstrin homology domain containing, family A member 6
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
RAB3A RAB3A, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RBM23 RNA binding motif protein 23
RRP1 ribosomal RNA processing 1
S100A6 S100 calcium binding protein A6
SCGB2A2 secretoglobin, family 2A, member 2
SETD8 SET domain containing (lysine methyltransferase) 8
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SNORA21 small nucleolar RNA, H/ACA box 21
SREK1IP1 SREK1-interacting protein 1
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TCTN1 tectonic family member 1
TH tyrosine hydroxylase
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast)
TMEM57 transmembrane protein 57
TMEM8A transmembrane protein 8A
TSPO translocator protein (18kDa)
TUBA3C tubulin, alpha 3c
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UPP1 uridine phosphorylase 1
USB1 U6 snRNA biogenesis 1
USP18 ubiquitin specific peptidase 18
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WDR91 WD repeat domain 91
ZC3H12A zinc finger CCCH-type containing 12A
ZNF747 zinc finger protein 747
ZNF804A zinc finger protein 804A