driven Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

314 genes co-occuring with the biological term driven in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ADAM15 ADAM metallopeptidase domain 15
ADARB1 adenosine deaminase, RNA-specific, B1
ADIPOQ adiponectin, C1Q and collagen domain containing
ADORA2A adenosine A2a receptor
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
APC adenomatous polyposis coli
APCS amyloid P component, serum
APLN apelin
APOB apolipoprotein B
APP amyloid beta (A4) precursor protein
ARRDC3 arrestin domain containing 3
ATF4 activating transcription factor 4
ATF5 activating transcription factor 5
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
ATXN3 ataxin 3
AURKA aurora kinase A
AXL AXL receptor tyrosine kinase
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BID BH3 interacting domain death agonist
BIRC5 baculoviral IAP repeat containing 5
BMP2 bone morphogenetic protein 2
BMP4 bone morphogenetic protein 4
BMP7 bone morphogenetic protein 7
BMPR1B bone morphogenetic protein receptor, type IB
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
C11ORF30 chromosome 11 open reading frame 30
C1QA complement component 1, q subcomponent, A chain
CAV1 caveolin 1, caveolae protein, 22kDa
CCL2 chemokine (C-C motif) ligand 2
CCND1 cyclin D1
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR8 chemokine (C-C motif) receptor 8
CD4 CD4 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD80 CD80 molecule
CD8A CD8a molecule
CD9 CD9 molecule
CD99 CD99 molecule
CDCP1 CUB domain containing protein 1
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDHR2 cadherin-related family member 2
CDHR5 cadherin-related family member 5
CDK6 cyclin-dependent kinase 6
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CELF2 CUGBP, Elav-like family member 2
CETP cholesteryl ester transfer protein, plasma
CHUK conserved helix-loop-helix ubiquitous kinase
CIITA class II, major histocompatibility complex, transactivator
CKS1B CDC28 protein kinase regulatory subunit 1B
CLCNKB chloride channel, voltage-sensitive Kb
COL2A1 collagen, type II, alpha 1
CRP C-reactive protein, pentraxin-related
CRTAM cytotoxic and regulatory T cell molecule
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CTCF CCCTC-binding factor (zinc finger protein)
CTCFL CCCTC-binding factor (zinc finger protein)-like
CTGF connective tissue growth factor
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CUL1 cullin 1
CUL5 cullin 5
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL11 chemokine (C-X-C motif) ligand 11
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR4 chemokine (C-X-C motif) receptor 4
CYBA cytochrome b-245, alpha polypeptide
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide
DNM1L dynamin 1-like
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DOT1L DOT1-like histone H3K79 methyltransferase
DRD2 dopamine receptor D2
DSG1 desmoglein 1
DSG2 desmoglein 2
DYM dymeclin
DYNLL1 dynein, light chain, LC8-type 1
E2F1 E2F transcription factor 1
EGFR epidermal growth factor receptor
ELAVL4 ELAV like neuron-specific RNA binding protein 4
EPAS1 endothelial PAS domain protein 1
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERCC2 excision repair cross-complementation group 2
ERCC3 excision repair cross-complementation group 3
ESR1 estrogen receptor 1
ETV6 ets variant 6
FER fer (fps/fes related) tyrosine kinase
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FGFR4 fibroblast growth factor receptor 4
FLT3 fms-related tyrosine kinase 3
FOSL1 FOS-like antigen 1
FOXA1 forkhead box A1
FOXO1 forkhead box O1
FOXP3 forkhead box P3
FTMT ferritin mitochondrial
FYN FYN proto-oncogene, Src family tyrosine kinase
GAB2 GRB2-associated binding protein 2
GALR3 galanin receptor 3
GBA glucosidase, beta, acid
GLI1 GLI family zinc finger 1
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GP6 glycoprotein VI (platelet)
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa
HAMP hepcidin antimicrobial peptide
HAVCR2 hepatitis A virus cellular receptor 2
HCRTR1 hypocretin (orexin) receptor 1
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIST2H2BE histone cluster 2, H2be
HLA-C major histocompatibility complex, class I, C
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-E major histocompatibility complex, class I, E
HLA-G major histocompatibility complex, class I, G
HMGB1 high mobility group box 1
HMOX1 heme oxygenase 1
HNF4A hepatocyte nuclear factor 4, alpha
HPSE heparanase
HRAS Harvey rat sarcoma viral oncogene homolog
HSF1 heat shock transcription factor 1
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular)
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGF2R insulin-like growth factor 2 receptor
IGL immunoglobulin lambda locus
IL17A interleukin 17A
IL1B interleukin 1, beta
IL21R interleukin 21 receptor
IL27 interleukin 27
IL6ST interleukin 6 signal transducer
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
INS insulin
IP6K1 inositol hexakisphosphate kinase 1
IRF4 interferon regulatory factor 4
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KDM2A lysine (K)-specific demethylase 2A
KDM3A lysine (K)-specific demethylase 3A
KEAP1 kelch-like ECH-associated protein 1
KIAA0391 KIAA0391
KIF5B kinesin family member 5B
KLC2 kinesin light chain 2
KLF11 Kruppel-like factor 11
KLF4 Kruppel-like factor 4 (gut)
KMT2D lysine (K)-specific methyltransferase 2D
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT14 keratin 14, type I
LCN2 lipocalin 2
LDHB lactate dehydrogenase B
LEF1 lymphoid enhancer-binding factor 1
LEP leptin
LRP1 low density lipoprotein receptor-related protein 1
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK7 mitogen-activated protein kinase 7
MAPK8 mitogen-activated protein kinase 8
MAPT microtubule-associated protein tau
MCL1 myeloid cell leukemia 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MET MET proto-oncogene, receptor tyrosine kinase
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR155 microRNA 155
MIR200C microRNA 200c
MIR205 microRNA 205
MIR21 microRNA 21
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MME membrane metallo-endopeptidase
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYD88 myeloid differentiation primary response 88
MYH11 myosin, heavy chain 11, smooth muscle
MYO1A myosin IA
MYOD1 myogenic differentiation 1
NCAM1 neural cell adhesion molecule 1
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
NF1 neurofibromin 1
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFYA nuclear transcription factor Y, alpha
NKX2-5 NK2 homeobox 5
NOX4 NADPH oxidase 4
NPPB natriuretic peptide B
NQO1 NAD(P)H dehydrogenase, quinone 1
NR0B2 nuclear receptor subfamily 0, group B, member 2
NR1H3 nuclear receptor subfamily 1, group H, member 3
NR1H4 nuclear receptor subfamily 1, group H, member 4
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NSD1 nuclear receptor binding SET domain protein 1
NUSAP1 nucleolar and spindle associated protein 1
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
PADI3 peptidyl arginine deiminase, type III
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAX2 paired box 2
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PDGFC platelet derived growth factor C
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDZK1IP1 PDZK1 interacting protein 1
PER3 period circadian clock 3
PGR progesterone receptor
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PLAUR plasminogen activator, urokinase receptor
PLXNB1 plexin B1
PNPLA3 patatin-like phospholipase domain containing 3
POLI polymerase (DNA directed) iota
PPARA peroxisome proliferator-activated receptor alpha
PPARG peroxisome proliferator-activated receptor gamma
PRKCD protein kinase C, delta
PRKCE protein kinase C, epsilon
PRKG1 protein kinase, cGMP-dependent, type I
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2 protein tyrosine kinase 2
RB1 retinoblastoma 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RHAG Rh-associated glycoprotein
RNF20 ring finger protein 20, E3 ubiquitin protein ligase
RNF40 ring finger protein 40, E3 ubiquitin protein ligase
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RSF1 remodeling and spacing factor 1
RUNX1 runt-related transcription factor 1
RXRA retinoid X receptor, alpha
SAMHD1 SAM domain and HD domain 1
SDC1 syndecan 1
SELPLG selectin P ligand
SERPINA2 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene)
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
SIRPA signal-regulatory protein alpha
SIRPG signal-regulatory protein gamma
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SMAD1 SMAD family member 1
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMAD6 SMAD family member 6
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SNAI1 snail family zinc finger 1
SNAP25 synaptosomal-associated protein, 25kDa
SOD1 superoxide dismutase 1, soluble
SOST sclerostin
SP1 Sp1 transcription factor
SP3 Sp3 transcription factor
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPN sialophorin
SPTA1 spectrin, alpha, erythrocytic 1
SPTB spectrin, beta, erythrocytic
SSTR1 somatostatin receptor 1
STAG2 stromal antigen 2
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STK11 serine/threonine kinase 11
STMN1 stathmin 1
STX1A syntaxin 1A (brain)
SUMO1 small ubiquitin-like modifier 1
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae)
SYCE2 synaptonemal complex central element protein 2
TAC1 tachykinin, precursor 1
TBK1 TANK-binding kinase 1
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TERF2 telomeric repeat binding factor 2
TERT telomerase reverse transcriptase
TEX12 testis expressed 12
TGFB1 transforming growth factor, beta 1
TGFBI transforming growth factor, beta-induced, 68kDa
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THBS1 thrombospondin 1
THRB thyroid hormone receptor, beta
THY1 Thy-1 cell surface antigen
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR6 toll-like receptor 6
TMEM173 transmembrane protein 173
TMSB10 thymosin beta 10
TNF tumor necrosis factor
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TP53 tumor protein p53
TRB T cell receptor beta locus
VCAM1 vascular cell adhesion molecule 1
VEGFA vascular endothelial growth factor A
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
WIF1 WNT inhibitory factor 1
WNT5A wingless-type MMTV integration site family, member 5A
XBP1 X-box binding protein 1
XDH xanthine dehydrogenase
YAP1 Yes-associated protein 1
ZEB1 zinc finger E-box binding homeobox 1