| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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195 genes differentially expressed following the drofenine-2714 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB8 | ATP-binding cassette, sub-family B (MDR/TAP), member 8 |
| ACVR1B | activin A receptor, type IB |
| ADRB3 | adrenoceptor beta 3 |
| AIPL1 | aryl hydrocarbon receptor interacting protein-like 1 |
| AP1M2 | adaptor-related protein complex 1, mu 2 subunit |
| APOL2 | apolipoprotein L, 2 |
| AR | androgen receptor |
| ARID4B | AT rich interactive domain 4B (RBP1-like) |
| BAIAP2 | BAI1-associated protein 2 |
| BCL2L14 | BCL2-like 14 (apoptosis facilitator) |
| BEST1 | bestrophin 1 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| C1ORF68 | chromosome 1 open reading frame 68 |
| CACFD1 | calcium channel flower domain containing 1 |
| CCDC82 | coiled-coil domain containing 82 |
| CD27 | CD27 molecule |
| CIZ1 | CDKN1A interacting zinc finger protein 1 |
| CLTA | clathrin, light chain A |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CPSF1 | cleavage and polyadenylation specific factor 1, 160kDa |
| CXCR1 | chemokine (C-X-C motif) receptor 1 |
| DAPK1 | death-associated protein kinase 1 |
| DCTN2 | dynactin 2 (p50) |
| DMTN | dematin actin binding protein |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNAJC16 | DnaJ (Hsp40) homolog, subfamily C, member 16 |
| DOK5 | docking protein 5 |
| DRD5 | dopamine receptor D5 |
| EFNA3 | ephrin-A3 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 |
| EML2 | echinoderm microtubule associated protein like 2 |
| FBXO21 | F-box protein 21 |
| FGF17 | fibroblast growth factor 17 |
| FUT7 | fucosyltransferase 7 (alpha (1,3) fucosyltransferase) |
| GPR132 | G protein-coupled receptor 132 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 |
| GPRC5D | G protein-coupled receptor, class C, group 5, member D |
| HIPK3 | homeodomain interacting protein kinase 3 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HOXA11 | homeobox A11 |
| HSPA2 | heat shock 70kDa protein 2 |
| IFI44 | interferon-induced protein 44 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 |
| KIAA0513 | KIAA0513 |
| KLF6 | Kruppel-like factor 6 |
| LEFTY1 | left-right determination factor 1 |
| LMNA | lamin A/C |
| MC5R | melanocortin 5 receptor |
| MFAP5 | microfibrillar associated protein 5 |
| MGAT3 | mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MYH14 | myosin, heavy chain 14, non-muscle |
| MYOM1 | myomesin 1 |
| NCKAP1 | NCK-associated protein 1 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase |
| NELL2 | NEL-like 2 (chicken) |
| NKX2-5 | NK2 homeobox 5 |
| NRF1 | nuclear respiratory factor 1 |
| OR6A2 | olfactory receptor, family 6, subfamily A, member 2 |
| OTUB1 | OTU deubiquitinase, ubiquitin aldehyde binding 1 |
| PAPPA2 | pappalysin 2 |
| PCDHA6 | protocadherin alpha 6 |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) |
| POFUT2 | protein O-fucosyltransferase 2 |
| PRUNE | prune exopolyphosphatase |
| PSEN2 | presenilin 2 |
| PTPRF | protein tyrosine phosphatase, receptor type, F |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RENBP | renin binding protein |
| RHOD | ras homolog family member D |
| RORA | RAR-related orphan receptor A |
| RUNDC3A | RUN domain containing 3A |
| SCAMP5 | secretory carrier membrane protein 5 |
| SEC14L5 | SEC14-like 5 (S. cerevisiae) |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 |
| SLC25A30 | solute carrier family 25, member 30 |
| SLC35D1 | solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 |
| SOX13 | SRY (sex determining region Y)-box 13 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| SRRM2 | serine/arginine repetitive matrix 2 |
| SSX3 | synovial sarcoma, X breakpoint 3 |
| STAC | SH3 and cysteine rich domain |
| SYNM | synemin, intermediate filament protein |
| TMOD1 | tropomodulin 1 |
| TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) |
| TPH1 | tryptophan hydroxylase 1 |
| TRIM62 | tripartite motif containing 62 |
| TYMP | thymidine phosphorylase |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 |
| XDH | xanthine dehydrogenase |
| ZHX3 | zinc fingers and homeoboxes 3 |
| ZNF185 | zinc finger protein 185 (LIM domain) |
| Symbol | Name |
|---|---|
| ABCF3 | ATP-binding cassette, sub-family F (GCN20), member 3 |
| ACPP | acid phosphatase, prostate |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| AMDHD2 | amidohydrolase domain containing 2 |
| ANKRD36 | ankyrin repeat domain 36 |
| ANXA2P2 | annexin A2 pseudogene 2 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| C9ORF114 | chromosome 9 open reading frame 114 |
| CCDC85C | coiled-coil domain containing 85C |
| CDK3 | cyclin-dependent kinase 3 |
| CEP97 | centrosomal protein 97kDa |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 |
| CISH | cytokine inducible SH2-containing protein |
| CLEC2D | C-type lectin domain family 2, member D |
| CTSV | cathepsin V |
| DDN | dendrin |
| DENND5B | DENN/MADD domain containing 5B |
| DNAL4 | dynein, axonemal, light chain 4 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| DTX4 | deltex 4, E3 ubiquitin ligase |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 |
| FAM102A | family with sequence similarity 102, member A |
| FER | fer (fps/fes related) tyrosine kinase |
| FOXD1 | forkhead box D1 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) |
| GALK1 | galactokinase 1 |
| GCH1 | GTP cyclohydrolase 1 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPR75 | G protein-coupled receptor 75 |
| GRIP2 | glutamate receptor interacting protein 2 |
| GRPR | gastrin-releasing peptide receptor |
| GSTZ1 | glutathione S-transferase zeta 1 |
| HDAC7 | histone deacetylase 7 |
| HIST1H2AM | histone cluster 1, H2am |
| HIST1H2BI | histone cluster 1, H2bi |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IGSF6 | immunoglobulin superfamily, member 6 |
| IL4R | interleukin 4 receptor |
| INO80D | INO80 complex subunit D |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 |
| KIAA0319L | KIAA0319-like |
| KLHL36 | kelch-like family member 36 |
| LPPR3 | lipid phosphate phosphatase-related protein type 3 |
| LTBP3 | latent transforming growth factor beta binding protein 3 |
| LYPLA2P1 | lysophospholipase II pseudogene 1 |
| MAP3K3 | mitogen-activated protein kinase kinase kinase 3 |
| NAG18 | NAG18 mRNA |
| NBEA | neurobeachin |
| NCS1 | neuronal calcium sensor 1 |
| NHEJ1 | nonhomologous end-joining factor 1 |
| NME8 | NME/NM23 family member 8 |
| NOL10 | nucleolar protein 10 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| OLAH | oleoyl-ACP hydrolase |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PKD2L2 | polycystic kidney disease 2-like 2 |
| PLA2G1B | phospholipase A2, group IB (pancreas) |
| PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) |
| RAB3A | RAB3A, member RAS oncogene family |
| RCAN3 | RCAN family member 3 |
| REC8 | REC8 meiotic recombination protein |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| S1PR4 | sphingosine-1-phosphate receptor 4 |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SHARPIN | SHANK-associated RH domain interactor |
| SPATA1 | spermatogenesis associated 1 |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| ST8SIA5 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TAS2R10 | taste receptor, type 2, member 10 |
| TBL1Y | transducin (beta)-like 1, Y-linked |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TMEM209 | transmembrane protein 209 |
| TOR4A | torsin family 4, member A |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| USP6NL | USP6 N-terminal like |
| VASH1 | vasohibin 1 |
| ZBTB25 | zinc finger and BTB domain containing 25 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZNF250 | zinc finger protein 250 |
| ZNF747 | zinc finger protein 747 |