| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the drofenine-3455 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AKAP7 | A kinase (PRKA) anchor protein 7 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| ARHGAP35 | Rho GTPase activating protein 35 |
| ASIC1 | acid sensing (proton gated) ion channel 1 |
| ATF3 | activating transcription factor 3 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| CALD1 | caldesmon 1 |
| CCDC186 | coiled-coil domain containing 186 |
| CCNK | cyclin K |
| CD58 | CD58 molecule |
| CHRNA9 | cholinergic receptor, nicotinic, alpha 9 (neuronal) |
| COL11A2 | collagen, type XI, alpha 2 |
| CYLD | cylindromatosis (turban tumor syndrome) |
| DCAF15 | DDB1 and CUL4 associated factor 15 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DIO2 | deiodinase, iodothyronine, type II |
| DOK4 | docking protein 4 |
| EFNA3 | ephrin-A3 |
| EGR1 | early growth response 1 |
| ENTPD4 | ectonucleoside triphosphate diphosphohydrolase 4 |
| EPOR | erythropoietin receptor |
| EPX | eosinophil peroxidase |
| FADS3 | fatty acid desaturase 3 |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FGF18 | fibroblast growth factor 18 |
| FGF6 | fibroblast growth factor 6 |
| FPR3 | formyl peptide receptor 3 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GTPBP3 | GTP binding protein 3 (mitochondrial) |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HIST1H1D | histone cluster 1, H1d |
| HRK | harakiri, BCL2 interacting protein |
| ICAM1 | intercellular adhesion molecule 1 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IL5RA | interleukin 5 receptor, alpha |
| INHBE | inhibin, beta E |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KIF5A | kinesin family member 5A |
| KLHL22 | kelch-like family member 22 |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 |
| LHX6 | LIM homeobox 6 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAPRE3 | microtubule-associated protein, RP/EB family, member 3 |
| MARC2 | mitochondrial amidoxime reducing component 2 |
| MCOLN1 | mucolipin 1 |
| MED1 | mediator complex subunit 1 |
| MEFV | Mediterranean fever |
| MMP13 | matrix metallopeptidase 13 |
| NEURL1 | neuralized E3 ubiquitin protein ligase 1 |
| NF1 | neurofibromin 1 |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| OLFML2A | olfactomedin-like 2A |
| PICK1 | protein interacting with PRKCA 1 |
| PIGC | phosphatidylinositol glycan anchor biosynthesis, class C |
| PIP | prolactin-induced protein |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A |
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta |
| PSG9 | pregnancy specific beta-1-glycoprotein 9 |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| RASAL2 | RAS protein activator like 2 |
| RNF31 | ring finger protein 31 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| SATB2 | SATB homeobox 2 |
| SDC3 | syndecan 3 |
| SGSM3 | small G protein signaling modulator 3 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| SMARCD1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 |
| ST3GAL2 | ST3 beta-galactoside alpha-2,3-sialyltransferase 2 |
| STOML1 | stomatin (EPB72)-like 1 |
| STON1 | stonin 1 |
| STS | steroid sulfatase (microsomal), isozyme S |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TH | tyrosine hydroxylase |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TRAF2 | TNF receptor-associated factor 2 |
| TRIM3 | tripartite motif containing 3 |
| TRIM36 | tripartite motif containing 36 |
| TRMT44 | tRNA methyltransferase 44 homolog (S. cerevisiae) |
| VLDLR | very low density lipoprotein receptor |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
| ZEB1 | zinc finger E-box binding homeobox 1 |
| ZHX3 | zinc fingers and homeoboxes 3 |
| ZNF10 | zinc finger protein 10 |
| ZNF202 | zinc finger protein 202 |
| ZNF862 | zinc finger protein 862 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| ABLIM3 | actin binding LIM protein family, member 3 |
| AMDHD2 | amidohydrolase domain containing 2 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 |
| BTBD3 | BTB (POZ) domain containing 3 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C2ORF54 | chromosome 2 open reading frame 54 |
| CDC37L1 | cell division cycle 37-like 1 |
| CDK3 | cyclin-dependent kinase 3 |
| CLDND1 | claudin domain containing 1 |
| CLK1 | CDC-like kinase 1 |
| CORT | cortistatin |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CRY2 | cryptochrome circadian clock 2 |
| CRYBG3 | beta-gamma crystallin domain containing 3 |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| DMC1 | DNA meiotic recombinase 1 |
| ECSIT | ECSIT signalling integrator |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 |
| FAAH | fatty acid amide hydrolase |
| FANCC | Fanconi anemia, complementation group C |
| FANCE | Fanconi anemia, complementation group E |
| FBRS | fibrosin |
| FBXO31 | F-box protein 31 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FCHO1 | FCH domain only 1 |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HDAC4 | histone deacetylase 4 |
| HIRA | histone cell cycle regulator |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H2BE | histone cluster 1, H2be |
| HIST1H3B | histone cluster 1, H3b |
| HMG20A | high mobility group 20A |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KCTD3 | potassium channel tetramerization domain containing 3 |
| KLHL2 | kelch-like family member 2 |
| KLHL26 | kelch-like family member 26 |
| L2HGDH | L-2-hydroxyglutarate dehydrogenase |
| LIG1 | ligase I, DNA, ATP-dependent |
| LRP6 | low density lipoprotein receptor-related protein 6 |
| LRRC61 | leucine rich repeat containing 61 |
| LRRC8E | leucine rich repeat containing 8 family, member E |
| NEK11 | NIMA-related kinase 11 |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NUBPL | nucleotide binding protein-like |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
| PARD6A | par-6 family cell polarity regulator alpha |
| PC | pyruvate carboxylase |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PLA2G12A | phospholipase A2, group XIIA |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PPIP5K2 | diphosphoinositol pentakisphosphate kinase 2 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| REEP4 | receptor accessory protein 4 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SIRT6 | sirtuin 6 |
| SLC26A6 | solute carrier family 26 (anion exchanger), member 6 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SOWAHC | sosondowah ankyrin repeat domain family member C |
| SP1 | Sp1 transcription factor |
| SPATA2L | spermatogenesis associated 2-like |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| SYCP2 | synaptonemal complex protein 2 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| TCTN1 | tectonic family member 1 |
| TET3 | tet methylcytosine dioxygenase 3 |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TMEM2 | transmembrane protein 2 |
| TMEM260 | transmembrane protein 260 |
| TMOD3 | tropomodulin 3 (ubiquitous) |
| TOM1 | target of myb1 (chicken) |
| TRIM25 | tripartite motif containing 25 |
| TRIM66 | tripartite motif containing 66 |
| TTC33 | tetratricopeptide repeat domain 33 |
| TUBGCP5 | tubulin, gamma complex associated protein 5 |
| URGCP | upregulator of cell proliferation |
| WDR47 | WD repeat domain 47 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| YEATS4 | YEATS domain containing 4 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZNF205 | zinc finger protein 205 |
| ZNF211 | zinc finger protein 211 |
| ZNF227 | zinc finger protein 227 |
| ZNF675 | zinc finger protein 675 |
| ZNHIT6 | zinc finger, HIT-type containing 6 |
