drofenine-6776 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the drofenine-6776 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
APOE apolipoprotein E
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ATAT1 alpha tubulin acetyltransferase 1
ATF3 activating transcription factor 3
BAAT bile acid CoA:amino acid N-acyltransferase
BIRC3 baculoviral IAP repeat containing 3
BMP1 bone morphogenetic protein 1
CALD1 caldesmon 1
CD58 CD58 molecule
CD70 CD70 molecule
CDK13 cyclin-dependent kinase 13
CHKB choline kinase beta
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CXCR4 chemokine (C-X-C motif) receptor 4
DCTN1 dynactin 1
DDIT4 DNA-damage-inducible transcript 4
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DOCK5 dedicator of cytokinesis 5
DOPEY2 dopey family member 2
EGR1 early growth response 1
EHBP1L1 EH domain binding protein 1-like 1
ELSPBP1 epididymal sperm binding protein 1
FBXO4 F-box protein 4
FGF18 fibroblast growth factor 18
FOS FBJ murine osteosarcoma viral oncogene homolog
FSCN3 fascin actin-bundling protein 3, testicular
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
GBP1 guanylate binding protein 1, interferon-inducible
GJA9 gap junction protein, alpha 9, 59kDa
GPC3 glypican 3
GSAP gamma-secretase activating protein
HIST1H1E histone cluster 1, H1e
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
ICAM1 intercellular adhesion molecule 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
IL17RC interleukin 17 receptor C
IL6R interleukin 6 receptor
IRF9 interferon regulatory factor 9
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
JAK2 Janus kinase 2
JAKMIP2 janus kinase and microtubule interacting protein 2
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KAT6A K(lysine) acetyltransferase 6A
KIR3DX1 killer cell immunoglobulin-like receptor, three domains, X1
KLHL24 kelch-like family member 24
LAMC2 laminin, gamma 2
LOC157562 uncharacterized LOC157562
LONRF3 LON peptidase N-terminal domain and ring finger 3
LRRC8B leucine rich repeat containing 8 family, member B
LYST lysosomal trafficking regulator
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MED25 mediator complex subunit 25
MMP19 matrix metallopeptidase 19
N4BP1 NEDD4 binding protein 1
NF1 neurofibromin 1
NFIB nuclear factor I/B
NPAS3 neuronal PAS domain protein 3
NUPR1 nuclear protein, transcriptional regulator, 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OASL 2'-5'-oligoadenylate synthetase-like
PARD6B par-6 family cell polarity regulator beta
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PDLIM5 PDZ and LIM domain 5
PGAP1 post-GPI attachment to proteins 1
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PLEC plectin
PLXND1 plexin D1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PRDM2 PR domain containing 2, with ZNF domain
PRKCE protein kinase C, epsilon
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RND1 Rho family GTPase 1
RREB1 ras responsive element binding protein 1
SCGB2A2 secretoglobin, family 2A, member 2
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SPON2 spondin 2, extracellular matrix protein
SSTR5 somatostatin receptor 5
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TBC1D2B TBC1 domain family, member 2B
TCF3 transcription factor 3
TGFBR3 transforming growth factor, beta receptor III
TJAP1 tight junction associated protein 1 (peripheral)
TJP3 tight junction protein 3
TLR2 toll-like receptor 2
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TTC38 tetratricopeptide repeat domain 38
VASH2 vasohibin 2
VWA5A von Willebrand factor A domain containing 5A
WDR62 WD repeat domain 62
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ACAD10 acyl-CoA dehydrogenase family, member 10
ACTG2 actin, gamma 2, smooth muscle, enteric
ANKRD40 ankyrin repeat domain 40
ANXA2P3 annexin A2 pseudogene 3
ARC activity-regulated cytoskeleton-associated protein
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BBS1 Bardet-Biedl syndrome 1
BMP4 bone morphogenetic protein 4
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBX4 chromobox homolog 4
CCDC134 coiled-coil domain containing 134
CCDC88C coiled-coil domain containing 88C
CD82 CD82 molecule
CDK3 cyclin-dependent kinase 3
CFD complement factor D (adipsin)
CHRM3 cholinergic receptor, muscarinic 3
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CIDEB cell death-inducing DFFA-like effector b
CIDEC cell death-inducing DFFA-like effector c
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CPPED1 calcineurin-like phosphoesterase domain containing 1
CPSF3L cleavage and polyadenylation specific factor 3-like
CRY2 cryptochrome circadian clock 2
CRYBG3 beta-gamma crystallin domain containing 3
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DAGLA diacylglycerol lipase, alpha
EDC3 enhancer of mRNA decapping 3
ELAVL3 ELAV like neuron-specific RNA binding protein 3
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ERN2 endoplasmic reticulum to nucleus signaling 2
ETAA1 Ewing tumor-associated antigen 1
FA2H fatty acid 2-hydroxylase
FAM63A family with sequence similarity 63, member A
FLT4 fms-related tyrosine kinase 4
FMO4 flavin containing monooxygenase 4
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPR27 G protein-coupled receptor 27
GSTCD glutathione S-transferase, C-terminal domain containing
GTF2I general transcription factor IIi
HSPA1L heat shock 70kDa protein 1-like
IPO13 importin 13
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
JMJD4 jumonji domain containing 4
KDM5C lysine (K)-specific demethylase 5C
KLHL12 kelch-like family member 12
KLHL26 kelch-like family member 26
KLHL28 kelch-like family member 28
LGALS4 lectin, galactoside-binding, soluble, 4
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LOC730101 uncharacterized LOC730101
LYRM9 LYR motif containing 9
MAN2C1 mannosidase, alpha, class 2C, member 1
MEFV Mediterranean fever
MFAP2 microfibrillar-associated protein 2
MTERF1 mitochondrial transcription termination factor 1
NEK11 NIMA-related kinase 11
NIPAL2 NIPA-like domain containing 2
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
OVGP1 oviductal glycoprotein 1, 120kDa
PCDH12 protocadherin 12
PDE12 phosphodiesterase 12
PYCRL pyrroline-5-carboxylate reductase-like
RAB30 RAB30, member RAS oncogene family
RFXAP regulatory factor X-associated protein
RHBG Rh family, B glycoprotein (gene/pseudogene)
RIBC2 RIB43A domain with coiled-coils 2
RNF170 ring finger protein 170
SCRN3 secernin 3
SETD1A SET domain containing 1A
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SORBS3 sorbin and SH3 domain containing 3
SPATA7 spermatogenesis associated 7
SPRR2B small proline-rich protein 2B
SPRY2 sprouty homolog 2 (Drosophila)
STMN3 stathmin-like 3
SYCP2 synaptonemal complex protein 2
TBL3 transducin (beta)-like 3
TCHH trichohyalin
TCTN1 tectonic family member 1
TGFB3 transforming growth factor, beta 3
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TNS2 tensin 2
TRAIP TRAF interacting protein
TSPYL2 TSPY-like 2
USB1 U6 snRNA biogenesis 1
WDR91 WD repeat domain 91
XAB2 XPA binding protein 2
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF35 zinc finger protein 35
ZNF442 zinc finger protein 442
ZNF573 zinc finger protein 573
ZW10 zw10 kinetochore protein