droperidol-1290 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the droperidol-1290 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ATP2A3 ATPase, Ca++ transporting, ubiquitous
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
CAPN2 calpain 2, (m/II) large subunit
CDADC1 cytidine and dCMP deaminase domain containing 1
CHML choroideremia-like (Rab escort protein 2)
CLEC4A C-type lectin domain family 4, member A
CREM cAMP responsive element modulator
CYB561 cytochrome b561
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DAPK1 death-associated protein kinase 1
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DSCR3 Down syndrome critical region 3
ERAP1 endoplasmic reticulum aminopeptidase 1
F12 coagulation factor XII (Hageman factor)
FBXW11 F-box and WD repeat domain containing 11
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GFOD2 glucose-fructose oxidoreductase domain containing 2
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GK3P glycerol kinase 3 pseudogene
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPATCH3 G patch domain containing 3
GUSBP3 glucuronidase, beta pseudogene 3
HIPK3 homeodomain interacting protein kinase 3
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IL6R interleukin 6 receptor
INHBA inhibin, beta A
IPO8 importin 8
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KLF6 Kruppel-like factor 6
LDB1 LIM domain binding 1
LIG4 ligase IV, DNA, ATP-dependent
LIN7A lin-7 homolog A (C. elegans)
MAN1A1 mannosidase, alpha, class 1A, member 1
MAN1C1 mannosidase, alpha, class 1C, member 1
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAPK14 mitogen-activated protein kinase 14
METTL2B methyltransferase like 2B
METTL5 methyltransferase like 5
MOCS3 molybdenum cofactor synthesis 3
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
MYOZ3 myozenin 3
NBPF10 neuroblastoma breakpoint family, member 10
NCBP1 nuclear cap binding protein subunit 1, 80kDa
NEK1 NIMA-related kinase 1
NFYA nuclear transcription factor Y, alpha
NREP neuronal regeneration related protein
NRP1 neuropilin 1
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1
NUP160 nucleoporin 160kDa
NXT2 nuclear transport factor 2-like export factor 2
PEX11A peroxisomal biogenesis factor 11 alpha
PGM3 phosphoglucomutase 3
PHC1 polyhomeotic homolog 1 (Drosophila)
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PITX2 paired-like homeodomain 2
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PTAFR platelet-activating factor receptor
PTCRA pre T-cell antigen receptor alpha
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTPRA protein tyrosine phosphatase, receptor type, A
RAB23 RAB23, member RAS oncogene family
RCAN1 regulator of calcineurin 1
RPS2 ribosomal protein S2
SAP30 Sin3A-associated protein, 30kDa
SC5D sterol-C5-desaturase
SCCPDH saccharopine dehydrogenase (putative)
SLC38A6 solute carrier family 38, member 6
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLITRK5 SLIT and NTRK-like family, member 5
SNX29P2 sorting nexin 29 pseudogene 2
SPAST spastin
SPATA5L1 spermatogenesis associated 5-like 1
SPRYD7 SPRY domain containing 7
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TCTN2 tectonic family member 2
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TMC7 transmembrane channel-like 7
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TWIST1 twist family bHLH transcription factor 1
UNC45A unc-45 homolog A (C. elegans)
UTRN utrophin
VDAC3 voltage-dependent anion channel 3
WSB1 WD repeat and SOCS box containing 1
ZBTB40 zinc finger and BTB domain containing 40
ZFAND5 zinc finger, AN1-type domain 5
ZNF10 zinc finger protein 10
ZNF322P1 zinc finger protein 322 pseudogene 1
ZNF468 zinc finger protein 468
ZNF493 zinc finger protein 493
ZNF668 zinc finger protein 668

decreased expression

Symbol Name
ADAP1 ArfGAP with dual PH domains 1
ARID5A AT rich interactive domain 5A (MRF1-like)
ASGR2 asialoglycoprotein receptor 2
ATG9A autophagy related 9A
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BATF basic leucine zipper transcription factor, ATF-like
BBC3 BCL2 binding component 3
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
C5AR1 complement component 5a receptor 1
C5ORF45 chromosome 5 open reading frame 45
C6ORF47 chromosome 6 open reading frame 47
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCDC69 coiled-coil domain containing 69
CCNJ cyclin J
CDIP1 cell death-inducing p53 target 1
CENPT centromere protein T
CHKB choline kinase beta
CLASRP CLK4-associating serine/arginine rich protein
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CTDNEP1 CTD nuclear envelope phosphatase 1
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DHRS9 dehydrogenase/reductase (SDR family) member 9
DVL1 dishevelled segment polarity protein 1
E4F1 E4F transcription factor 1
ECHDC2 enoyl CoA hydratase domain containing 2
EDC4 enhancer of mRNA decapping 4
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EHBP1L1 EH domain binding protein 1-like 1
ETV4 ets variant 4
FAM173A family with sequence similarity 173, member A
FAM188A family with sequence similarity 188, member A
FAM193B family with sequence similarity 193, member B
FAM86B1 family with sequence similarity 86, member B1
FCHO1 FCH domain only 1
FHIT fragile histidine triad
FHL3 four and a half LIM domains 3
FPGS folylpolyglutamate synthase
FURIN furin (paired basic amino acid cleaving enzyme)
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GGTLC1 gamma-glutamyltransferase light chain 1
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GNL1 guanine nucleotide binding protein-like 1
HHLA3 HERV-H LTR-associating 3
ITPKC inositol-trisphosphate 3-kinase C
JUP junction plakoglobin
KIAA0556 KIAA0556
KIAA0894 KIAA0894 protein
LPAR4 lysophosphatidic acid receptor 4
LRP3 low density lipoprotein receptor-related protein 3
LY6E lymphocyte antigen 6 complex, locus E
MAN2B1 mannosidase, alpha, class 2B, member 1
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MAPKAP1 mitogen-activated protein kinase associated protein 1
MAPKBP1 mitogen-activated protein kinase binding protein 1
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MXD3 MAX dimerization protein 3
MYL5 myosin, light chain 5, regulatory
NABP2 nucleic acid binding protein 2
NAT6 N-acetyltransferase 6 (GCN5-related)
NTSR1 neurotensin receptor 1 (high affinity)
NUBPL nucleotide binding protein-like
OTUD3 OTU deubiquitinase 3
PGPEP1 pyroglutamyl-peptidase I
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHO1 pleckstrin homology domain containing, family O member 1
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
PNPLA6 patatin-like phospholipase domain containing 6
POMZP3 POM121 and ZP3 fusion
POR P450 (cytochrome) oxidoreductase
PRKCSH protein kinase C substrate 80K-H
PTDSS2 phosphatidylserine synthase 2
PYCR1 pyrroline-5-carboxylate reductase 1
RABGGTA Rab geranylgeranyltransferase, alpha subunit
RHOBTB2 Rho-related BTB domain containing 2
RPA4 replication protein A4, 30kDa
RPP25 ribonuclease P/MRP 25kDa subunit
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
SIRT2 sirtuin 2
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SPINT1 serine peptidase inhibitor, Kunitz type 1
STON1 stonin 1
TM7SF3 transmembrane 7 superfamily member 3
TNNT1 troponin T type 1 (skeletal, slow)
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TSPYL2 TSPY-like 2
TUBA3C tubulin, alpha 3c
TUBA3D tubulin, alpha 3d
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
ZNF134 zinc finger protein 134
ZNF692 zinc finger protein 692
ZNF787 zinc finger protein 787