droperidol-2645 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the droperidol-2645 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A1CF APOBEC1 complementation factor
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ADAM19 ADAM metallopeptidase domain 19
ADARB1 adenosine deaminase, RNA-specific, B1
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ANKMY1 ankyrin repeat and MYND domain containing 1
APC adenomatous polyposis coli
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ATAD5 ATPase family, AAA domain containing 5
ATG10 autophagy related 10
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BEGAIN brain-enriched guanylate kinase-associated
C11ORF21 chromosome 11 open reading frame 21
C3 complement component 3
CA1 carbonic anhydrase I
CACYBP calcyclin binding protein
CAMK4 calcium/calmodulin-dependent protein kinase IV
CASP2 caspase 2, apoptosis-related cysteine peptidase
CST1 cystatin SN
CTIF CBP80/20-dependent translation initiation factor
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
EGF epidermal growth factor
EHBP1L1 EH domain binding protein 1-like 1
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1)
EPHX2 epoxide hydrolase 2, cytoplasmic
EPOR erythropoietin receptor
F2RL2 coagulation factor II (thrombin) receptor-like 2
F5 coagulation factor V (proaccelerin, labile factor)
FAM131A family with sequence similarity 131, member A
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FFAR3 free fatty acid receptor 3
FRMD8 FERM domain containing 8
GFER growth factor, augmenter of liver regeneration
GGT1 gamma-glutamyltransferase 1
GGTLC1 gamma-glutamyltransferase light chain 1
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPATCH4 G patch domain containing 4
HOXD1 homeobox D1
HSPB6 heat shock protein, alpha-crystallin-related, B6
IGFBP5 insulin-like growth factor binding protein 5
INPP5J inositol polyphosphate-5-phosphatase J
INSL4 insulin-like 4 (placenta)
ITGA7 integrin, alpha 7
ITGB4 integrin, beta 4
JUN jun proto-oncogene
KDM8 lysine (K)-specific demethylase 8
KLHL35 kelch-like family member 35
KRT31 keratin 31, type I
LIMCH1 LIM and calponin homology domains 1
NAT6 N-acetyltransferase 6 (GCN5-related)
NCOR2 nuclear receptor corepressor 2
NOS1 nitric oxide synthase 1 (neuronal)
NR6A1 nuclear receptor subfamily 6, group A, member 1
NXPE3 neurexophilin and PC-esterase domain family, member 3
OVOL2 ovo-like zinc finger 2
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PARVA parvin, alpha
PCDH12 protocadherin 12
PDE10A phosphodiesterase 10A
PDE4DIP phosphodiesterase 4D interacting protein
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLCD1 phospholipase C, delta 1
PLEKHS1 pleckstrin homology domain containing, family S member 1
PLK4 polo-like kinase 4
PON3 paraoxonase 3
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic)
RPL35A ribosomal protein L35a
RUNX1 runt-related transcription factor 1
RYR2 ryanodine receptor 2 (cardiac)
SCRG1 stimulator of chondrogenesis 1
SDC2 syndecan 2
SFTPB surfactant protein B
SIGLEC7 sialic acid binding Ig-like lectin 7
SNW1 SNW domain containing 1
SPATA5L1 spermatogenesis associated 5-like 1
STK3 serine/threonine kinase 3
TADA2A transcriptional adaptor 2A
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TAT tyrosine aminotransferase
TCP11L1 t-complex 11, testis-specific-like 1
TFCP2L1 transcription factor CP2-like 1
TIGD6 tigger transposable element derived 6
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TRIM10 tripartite motif containing 10
UPK2 uroplakin 2
USP34 ubiquitin specific peptidase 34
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
VPRBP Vpr (HIV-1) binding protein
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WIPI2 WD repeat domain, phosphoinositide interacting 2
ZNF747 zinc finger protein 747
ZNF778 zinc finger protein 778

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ANKFY1 ankyrin repeat and FYVE domain containing 1
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARID3A AT rich interactive domain 3A (BRIGHT-like)
BMP4 bone morphogenetic protein 4
C2ORF54 chromosome 2 open reading frame 54
C5AR2 complement component 5a receptor 2
CCDC9 coiled-coil domain containing 9
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CDKL3 cyclin-dependent kinase-like 3
CGA glycoprotein hormones, alpha polypeptide
CHML choroideremia-like (Rab escort protein 2)
CLCF1 cardiotrophin-like cytokine factor 1
CLCN2 chloride channel, voltage-sensitive 2
CLSPN claspin
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DAGLA diacylglycerol lipase, alpha
DCP1A decapping mRNA 1A
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DOC2A double C2-like domains, alpha
DTX4 deltex 4, E3 ubiquitin ligase
DYSF dysferlin
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EMID1 EMI domain containing 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
EXD3 exonuclease 3'-5' domain containing 3
F2R coagulation factor II (thrombin) receptor
F3 coagulation factor III (thromboplastin, tissue factor)
FBRS fibrosin
FER fer (fps/fes related) tyrosine kinase
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
GRPR gastrin-releasing peptide receptor
HOXC10 homeobox C10
HSPA1L heat shock 70kDa protein 1-like
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFI35 interferon-induced protein 35
IGFBP6 insulin-like growth factor binding protein 6
IRF1 interferon regulatory factor 1
KIAA0513 KIAA0513
KIAA0894 KIAA0894 protein
KIZ kizuna centrosomal protein
KLHL21 kelch-like family member 21
KLHL25 kelch-like family member 25
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LZTR1 leucine-zipper-like transcription regulator 1
MANBA mannosidase, beta A, lysosomal
MED15 mediator complex subunit 15
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NPM3 nucleophosmin/nucleoplasmin 3
NR1H3 nuclear receptor subfamily 1, group H, member 3
NRSN2 neurensin 2
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PELI1 pellino E3 ubiquitin protein ligase 1
PEX26 peroxisomal biogenesis factor 26
PPT2 palmitoyl-protein thioesterase 2
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RCOR3 REST corepressor 3
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RIN2 Ras and Rab interactor 2
RNF122 ring finger protein 122
RNF39 ring finger protein 39
RPAP2 RNA polymerase II associated protein 2
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SHPK sedoheptulokinase
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SOX3 SRY (sex determining region Y)-box 3
SPINK5 serine peptidase inhibitor, Kazal type 5
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STX5 syntaxin 5
TEAD3 TEA domain family member 3
TMEM183A transmembrane protein 183A
TMEM62 transmembrane protein 62
TP53I3 tumor protein p53 inducible protein 3
TRAF2 TNF receptor-associated factor 2
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TSPYL2 TSPY-like 2
TUBA3C tubulin, alpha 3c
ULBP2 UL16 binding protein 2
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
ZBED1 zinc finger, BED-type containing 1
ZC3H12A zinc finger CCCH-type containing 12A
ZDHHC14 zinc finger, DHHC-type containing 14
ZMAT5 zinc finger, matrin-type 5
ZNF34 zinc finger protein 34
ZNF623 zinc finger protein 623
ZNF768 zinc finger protein 768