droperidol-4629 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the droperidol-4629 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ABHD8 abhydrolase domain containing 8
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADARB1 adenosine deaminase, RNA-specific, B1
ADRA1A adrenoceptor alpha 1A
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
APOB apolipoprotein B
ARTN artemin
BHMT2 betaine--homocysteine S-methyltransferase 2
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CADM1 cell adhesion molecule 1
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCL11 chemokine (C-C motif) ligand 11
CD53 CD53 molecule
CDH8 cadherin 8, type 2
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CELA2A chymotrypsin-like elastase family, member 2A
CHGA chromogranin A
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
COL9A2 collagen, type IX, alpha 2
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CTRC chymotrypsin C (caldecrin)
CYTH1 cytohesin 1
ERN2 endoplasmic reticulum to nucleus signaling 2
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit
F2RL3 coagulation factor II (thrombin) receptor-like 3
FAM63A family with sequence similarity 63, member A
FLJ11292
FLT3LG fms-related tyrosine kinase 3 ligand
FOXN3 forkhead box N3
FUZ fuzzy planar cell polarity protein
GPR27 G protein-coupled receptor 27
GRM8 glutamate receptor, metabotropic 8
GTPBP1 GTP binding protein 1
HESX1 HESX homeobox 1
HOXA6 homeobox A6
HSF1 heat shock transcription factor 1
IDUA iduronidase, alpha-L-
IFIH1 interferon induced with helicase C domain 1
IFT54 intraflagellar transport 54
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KALRN kalirin, RhoGEF kinase
KCTD14 potassium channel tetramerization domain containing 14
KHSRP KH-type splicing regulatory protein
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KRAS Kirsten rat sarcoma viral oncogene homolog
KSR1 kinase suppressor of ras 1
LEF1 lymphoid enhancer-binding factor 1
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LOC390998 ribosomal protein L10 pseudogene
LOC57399 uncharacterized gastric protein ZA52P
LPPR4 lipid phosphate phosphatase-related protein type 4
MEG3 maternally expressed 3 (non-protein coding)
MPL MPL proto-oncogene, thrombopoietin receptor
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
NEUROD4 neuronal differentiation 4
NPIPB3 nuclear pore complex interacting protein family, member B3
NRXN2 neurexin 2
PACRG PARK2 co-regulated
PARP8 poly (ADP-ribose) polymerase family, member 8
PCDH11Y protocadherin 11 Y-linked
PDLIM3 PDZ and LIM domain 3
PHLDB1 pleckstrin homology-like domain, family B, member 1
PRB1 proline-rich protein BstNI subfamily 1
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PROL1 proline rich, lacrimal 1
PTPRF protein tyrosine phosphatase, receptor type, F
RAP2B RAP2B, member of RAS oncogene family
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RPH3AL rabphilin 3A-like (without C2 domains)
RPL18 ribosomal protein L18
SCG2 secretogranin II
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOCS3 suppressor of cytokine signaling 3
SOCS6 suppressor of cytokine signaling 6
SPTBN5 spectrin, beta, non-erythrocytic 5
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SYCP2 synaptonemal complex protein 2
TAAR5 trace amine associated receptor 5
TAL1 T-cell acute lymphocytic leukemia 1
TAPBP TAP binding protein (tapasin)
TBX2 T-box 2
TCF3 transcription factor 3
TGFB1 transforming growth factor, beta 1
TMEM246 transmembrane protein 246
TRIM14 tripartite motif containing 14
TSHR thyroid stimulating hormone receptor
TSPY1 testis specific protein, Y-linked 1
TXK TXK tyrosine kinase
UBE3A ubiquitin protein ligase E3A
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae)
ZBTB7A zinc finger and BTB domain containing 7A
ZNF467 zinc finger protein 467

decreased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABHD17B abhydrolase domain containing 17B
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACE angiotensin I converting enzyme
ADCY6 adenylate cyclase 6
ADGRB2 adhesion G protein-coupled receptor B2
AGO4 argonaute RISC catalytic component 4
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ALS2CL ALS2 C-terminal like
AMT aminomethyltransferase
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ANKRD36 ankyrin repeat domain 36
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
C11ORF30 chromosome 11 open reading frame 30
C7ORF69 chromosome 7 open reading frame 69
C9ORF40 chromosome 9 open reading frame 40
CA11 carbonic anhydrase XI
CARD8 caspase recruitment domain family, member 8
CDK6 cyclin-dependent kinase 6
CFAP44 cilia and flagella associated protein 44
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7
CHMP6 charged multivesicular body protein 6
CNR2 cannabinoid receptor 2 (macrophage)
CTSF cathepsin F
CTSK cathepsin K
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DMTN dematin actin binding protein
DNM3 dynamin 3
EGF epidermal growth factor
ERCC4 excision repair cross-complementation group 4
FAM13C family with sequence similarity 13, member C
FAM160B2 family with sequence similarity 160, member B2
FBRS fibrosin
FBXW12 F-box and WD repeat domain containing 12
FILIP1L filamin A interacting protein 1-like
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GSTA3 glutathione S-transferase alpha 3
HAMP hepcidin antimicrobial peptide
HIST1H3C histone cluster 1, H3c
HIST1H3I histone cluster 1, H3i
HOXA1 homeobox A1
HOXA4 homeobox A4
ICOS inducible T-cell co-stimulator
IL15RA interleukin 15 receptor, alpha
ITGB7 integrin, beta 7
KDM7A lysine (K)-specific demethylase 7A
KLF3 Kruppel-like factor 3 (basic)
KLHL28 kelch-like family member 28
KRT20 keratin 20, type I
LINC00341 long intergenic non-protein coding RNA 341
LINC00597 long intergenic non-protein coding RNA 597
LINS lines homolog (Drosophila)
LOC100287590 uncharacterized LOC100287590
LOC202181 SUMO-interacting motifs containing 1 pseudogene
MBTD1 mbt domain containing 1
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MRPL41 mitochondrial ribosomal protein L41
MYLIP myosin regulatory light chain interacting protein
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NPFFR1 neuropeptide FF receptor 1
NPPB natriuretic peptide B
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OSMR oncostatin M receptor
OSR2 odd-skipped related transciption factor 2
PLAG1 pleiomorphic adenoma gene 1
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PODXL2 podocalyxin-like 2
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
PRM2 protamine 2
PTK6 protein tyrosine kinase 6
PTPRS protein tyrosine phosphatase, receptor type, S
RABL6 RAB, member RAS oncogene family-like 6
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RIBC2 RIB43A domain with coiled-coils 2
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SPINK1 serine peptidase inhibitor, Kazal type 1
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TBX19 T-box 19
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TSNAXIP1 translin-associated factor X interacting protein 1
TTLL1 tubulin tyrosine ligase-like family member 1
USB1 U6 snRNA biogenesis 1
VWA1 von Willebrand factor A domain containing 1
WASF1 WAS protein family, member 1
WNT10B wingless-type MMTV integration site family, member 10B
ZBTB44 zinc finger and BTB domain containing 44
ZNF528 zinc finger protein 528