droperidol-5690 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the droperidol-5690 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
APOE apolipoprotein E
C22ORF24 chromosome 22 open reading frame 24
CALD1 caldesmon 1
CCDC181 coiled-coil domain containing 181
CCR2 chemokine (C-C motif) receptor 2
CD80 CD80 molecule
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CFAP69 cilia and flagella associated protein 69
CHAD chondroadherin
CHL1 cell adhesion molecule L1-like
CLCN4 chloride channel, voltage-sensitive 4
COL1A2 collagen, type I, alpha 2
COL5A2 collagen, type V, alpha 2
COL6A1 collagen, type VI, alpha 1
CORO7 coronin 7
CSTA cystatin A (stefin A)
CXCR3 chemokine (C-X-C motif) receptor 3
DCX doublecortin
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
DNAH3 dynein, axonemal, heavy chain 3
DSCC1 DNA replication and sister chromatid cohesion 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EFHC2 EF-hand domain (C-terminal) containing 2
EGFR epidermal growth factor receptor
ELAVL2 ELAV like neuron-specific RNA binding protein 2
EPYC epiphycan
EVI2B ecotropic viral integration site 2B
FBXO40 F-box protein 40
FOXD3 forkhead box D3
FRMPD1 FERM and PDZ domain containing 1
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GAMT guanidinoacetate N-methyltransferase
GPR68 G protein-coupled receptor 68
GRIK5 glutamate receptor, ionotropic, kainate 5
GRM8 glutamate receptor, metabotropic 8
GUK1 guanylate kinase 1
HFE hemochromatosis
HIST1H1B histone cluster 1, H1b
HR hair growth associated
HSPA12A heat shock 70kDa protein 12A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
ICAM1 intercellular adhesion molecule 1
ICOSLG inducible T-cell co-stimulator ligand
IGH immunoglobulin heavy locus
IL1R1 interleukin 1 receptor, type I
IL2RB interleukin 2 receptor, beta
KALRN kalirin, RhoGEF kinase
KIAA1644 KIAA1644
KLK13 kallikrein-related peptidase 13
LDLR low density lipoprotein receptor
LINC01587 long intergenic non-protein coding RNA 1587
LPAR1 lysophosphatidic acid receptor 1
LRP1 low density lipoprotein receptor-related protein 1
LRP12 low density lipoprotein receptor-related protein 12
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MYH15 myosin, heavy chain 15
MYO9B myosin IXB
NOL10 nucleolar protein 10
NOVA2 neuro-oncological ventral antigen 2
NR6A1 nuclear receptor subfamily 6, group A, member 1
NRXN3 neurexin 3
OR7A10 olfactory receptor, family 7, subfamily A, member 10
OSGIN1 oxidative stress induced growth inhibitor 1
PCDHB13 protocadherin beta 13
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PDLIM4 PDZ and LIM domain 4
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PLXNB1 plexin B1
PMEL premelanosome protein
POU6F2 POU class 6 homeobox 2
PPARD peroxisome proliferator-activated receptor delta
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PRDM14 PR domain containing 14
PRLR prolactin receptor
PRR5L proline rich 5 like
RAB30 RAB30, member RAS oncogene family
RBBP4 retinoblastoma binding protein 4
RGCC regulator of cell cycle
RUNX1 runt-related transcription factor 1
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SCARA3 scavenger receptor class A, member 3
SLA Src-like-adaptor
SLC17A2 solute carrier family 17, member 2
SLC43A3 solute carrier family 43, member 3
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SOX21 SRY (sex determining region Y)-box 21
SYNDIG1 synapse differentiation inducing 1
TAS2R1 taste receptor, type 2, member 1
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TEF thyrotrophic embryonic factor
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TOX3 TOX high mobility group box family member 3
TUBA4B tubulin, alpha 4b
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
ZNF639 zinc finger protein 639
ZNF767P zinc finger family member 767, pseudogene
ZNRF4 zinc and ring finger 4

decreased expression

Symbol Name
ABHD14A abhydrolase domain containing 14A
AFAP1 actin filament associated protein 1
ARMC6 armadillo repeat containing 6
ARRB1 arrestin, beta 1
ASPHD1 aspartate beta-hydroxylase domain containing 1
BCAS1 breast carcinoma amplified sequence 1
BCL9 B-cell CLL/lymphoma 9
BTF3P12 basic transcription factor 3 pseudogene 12
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C7ORF43 chromosome 7 open reading frame 43
CAPG capping protein (actin filament), gelsolin-like
CBX7 chromobox homolog 7
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC85C coiled-coil domain containing 85C
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CHKB choline kinase beta
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CLDN1 claudin 1
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
COCH cochlin
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DGAT1 diacylglycerol O-acyltransferase 1
DUSP8 dual specificity phosphatase 8
EAF2 ELL associated factor 2
FAAH fatty acid amide hydrolase
FAM160B2 family with sequence similarity 160, member B2
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FSTL3 follistatin-like 3 (secreted glycoprotein)
FUZ fuzzy planar cell polarity protein
FZD2 frizzled class receptor 2
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GNL1 guanine nucleotide binding protein-like 1
HDAC4 histone deacetylase 4
HMHA1 histocompatibility (minor) HA-1
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IGSF1 immunoglobulin superfamily, member 1
IRF6 interferon regulatory factor 6
KRT13 keratin 13, type I
LIG4 ligase IV, DNA, ATP-dependent
LOC202181 SUMO-interacting motifs containing 1 pseudogene
METTL16 methyltransferase like 16
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MNX1 motor neuron and pancreas homeobox 1
MOCS3 molybdenum cofactor synthesis 3
MSMB microseminoprotein, beta-
MUM1 melanoma associated antigen (mutated) 1
MXD3 MAX dimerization protein 3
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NFE2L3 nuclear factor, erythroid 2-like 3
NPFFR1 neuropeptide FF receptor 1
OSMR oncostatin M receptor
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PCBP4 poly(rC) binding protein 4
PCSK7 proprotein convertase subtilisin/kexin type 7
PGP phosphoglycolate phosphatase
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
POLL polymerase (DNA directed), lambda
POR P450 (cytochrome) oxidoreductase
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PTK6 protein tyrosine kinase 6
RAD54L2 RAD54-like 2 (S. cerevisiae)
RBL1 retinoblastoma-like 1
RHOF ras homolog family member F (in filopodia)
RIBC2 RIB43A domain with coiled-coils 2
RPH3AL rabphilin 3A-like (without C2 domains)
S100A4 S100 calcium binding protein A4
SCAMP4 secretory carrier membrane protein 4
SH2B3 SH2B adaptor protein 3
SH3GLB2 SH3-domain GRB2-like endophilin B2
SLC44A1 solute carrier family 44 (choline transporter), member 1
SND1-IT1 SND1 intronic transcript 1
SPIDR scaffolding protein involved in DNA repair
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SSBP3 single stranded DNA binding protein 3
STX5 syntaxin 5
TDRD1 tudor domain containing 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TNS2 tensin 2
TPCN1 two pore segment channel 1
TRAF2 TNF receptor-associated factor 2
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TUBGCP5 tubulin, gamma complex associated protein 5
UBTD1 ubiquitin domain containing 1
VWA1 von Willebrand factor A domain containing 1
WLS wntless Wnt ligand secretion mediator
WWC2 WW and C2 domain containing 2
XK X-linked Kx blood group
ZC3H3 zinc finger CCCH-type containing 3
ZNF136 zinc finger protein 136
ZNF211 zinc finger protein 211
ZNF329 zinc finger protein 329
ZNF74 zinc finger protein 74
ZNF747 zinc finger protein 747
ZNF862 zinc finger protein 862
ZNHIT2 zinc finger, HIT-type containing 2