dropropizine-7429 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the dropropizine-7429 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AIM1L absent in melanoma 1-like
AK1 adenylate kinase 1
AKAP17A A kinase (PRKA) anchor protein 17A
AKR1C2 aldo-keto reductase family 1, member C2
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
APOC4 apolipoprotein C-IV
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATRX alpha thalassemia/mental retardation syndrome X-linked
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BTG2 BTG family, member 2
CA12 carbonic anhydrase XII
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CBX7 chromobox homolog 7
CD79B CD79b molecule, immunoglobulin-associated beta
CLTA clathrin, light chain A
CNGB3 cyclic nucleotide gated channel beta 3
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CSPP1 centrosome and spindle pole associated protein 1
DCN decorin
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
DIEXF digestive organ expansion factor homolog (zebrafish)
DOK4 docking protein 4
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EFNA3 ephrin-A3
EPOR erythropoietin receptor
EPS8L1 EPS8-like 1
EXOC7 exocyst complex component 7
FADS3 fatty acid desaturase 3
FAM65A family with sequence similarity 65, member A
FASTKD2 FAST kinase domains 2
FLT4 fms-related tyrosine kinase 4
FSCN1 fascin actin-bundling protein 1
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GRTP1 growth hormone regulated TBC protein 1
HAUS5 HAUS augmin-like complex, subunit 5
HS6ST1 heparan sulfate 6-O-sulfotransferase 1
HSF1 heat shock transcription factor 1
HTT huntingtin
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
IRF1 interferon regulatory factor 1
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KRT6B keratin 6B, type II
LIMS2 LIM and senescent cell antigen-like domains 2
LONP2 lon peptidase 2, peroxisomal
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MAX MYC associated factor X
MBOAT2 membrane bound O-acyltransferase domain containing 2
MFAP3 microfibrillar-associated protein 3
MON1B MON1 secretory trafficking family member B
MPPED2 metallophosphoesterase domain containing 2
MRC2 mannose receptor, C type 2
MXD3 MAX dimerization protein 3
MZF1 myeloid zinc finger 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NPFFR1 neuropeptide FF receptor 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
OGFR opioid growth factor receptor
PAPPA2 pappalysin 2
PCNX pecanex homolog (Drosophila)
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
POLH polymerase (DNA directed), eta
PRF1 perforin 1 (pore forming protein)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PXDC1 PX domain containing 1
QKI QKI, KH domain containing, RNA binding
RAD54L2 RAD54-like 2 (S. cerevisiae)
RANBP3 RAN binding protein 3
RPAP2 RNA polymerase II associated protein 2
S100A8 S100 calcium binding protein A8
SIRAL2 SIR2 antiphage like 2
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SPTBN1 spectrin, beta, non-erythrocytic 1
ST20 suppressor of tumorigenicity 20
STS steroid sulfatase (microsomal), isozyme S
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRIM2 tripartite motif containing 2
USB1 U6 snRNA biogenesis 1
USP34 ubiquitin specific peptidase 34
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
YY1 YY1 transcription factor
ZBTB40 zinc finger and BTB domain containing 40
ZCCHC24 zinc finger, CCHC domain containing 24
ZKSCAN1 zinc finger with KRAB and SCAN domains 1
ZNF614 zinc finger protein 614
ZNF770 zinc finger protein 770

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADCY6 adenylate cyclase 6
ANXA2P3 annexin A2 pseudogene 3
ATG14 autophagy related 14
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
AXIN1 axin 1
BAGE B melanoma antigen
BCL9 B-cell CLL/lymphoma 9
C5 complement component 5
C7ORF43 chromosome 7 open reading frame 43
CALCOCO1 calcium binding and coiled-coil domain 1
CAMKMT calmodulin-lysine N-methyltransferase
CCDC186 coiled-coil domain containing 186
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CEP97 centrosomal protein 97kDa
CFD complement factor D (adipsin)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DDIT3 DNA-damage-inducible transcript 3
DGKD diacylglycerol kinase, delta 130kDa
DOCK1 dedicator of cytokinesis 1
ECHDC2 enoyl CoA hydratase domain containing 2
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EPPK1 epiplakin 1
ERMAP erythroblast membrane-associated protein (Scianna blood group)
EYA2 EYA transcriptional coactivator and phosphatase 2
FOSL1 FOS-like antigen 1
FURIN furin (paired basic amino acid cleaving enzyme)
GAN gigaxonin
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GRB7 growth factor receptor-bound protein 7
GYS1 glycogen synthase 1 (muscle)
HINFP histone H4 transcription factor
HIRA histone cell cycle regulator
HIST1H4D histone cluster 1, H4d
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
JADE1 jade family PHD finger 1
KCNK15 potassium channel, two pore domain subfamily K, member 15
KLHL21 kelch-like family member 21
LINS lines homolog (Drosophila)
LOC100287590 uncharacterized LOC100287590
LRRC61 leucine rich repeat containing 61
LZTFL1 leucine zipper transcription factor-like 1
MAP6D1 MAP6 domain containing 1
MCOLN1 mucolipin 1
METTL8 methyltransferase like 8
MID1IP1 MID1 interacting protein 1
MMD monocyte to macrophage differentiation-associated
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NT5C 5', 3'-nucleotidase, cytosolic
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PAQR3 progestin and adipoQ receptor family member III
PBLD phenazine biosynthesis-like protein domain containing
PC pyruvate carboxylase
PCF11 PCF11 cleavage and polyadenylation factor subunit
PCSK7 proprotein convertase subtilisin/kexin type 7
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PGPEP1 pyroglutamyl-peptidase I
PHC1 polyhomeotic homolog 1 (Drosophila)
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PLD3 phospholipase D family, member 3
PLXNA3 plexin A3
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PRR14L proline rich 14-like
QSOX1 quiescin Q6 sulfhydryl oxidase 1
RAP1GAP2 RAP1 GTPase activating protein 2
RCOR3 REST corepressor 3
RECQL4 RecQ protein-like 4
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RNF126P1 ring finger protein 126 pseudogene 1
S100A4 S100 calcium binding protein A4
SCHIP1 schwannomin interacting protein 1
SCML2 sex comb on midleg-like 2 (Drosophila)
SCUBE2 signal peptide, CUB domain, EGF-like 2
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SREK1IP1 SREK1-interacting protein 1
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TGFBI transforming growth factor, beta-induced, 68kDa
TMEM209 transmembrane protein 209
TPCN1 two pore segment channel 1
TPST2 tyrosylprotein sulfotransferase 2
TRABD TraB domain containing
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TUBA3D tubulin, alpha 3d
UBXN6 UBX domain protein 6
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF248 zinc finger protein 248
ZNF250 zinc finger protein 250
ZNF286A zinc finger protein 286A
ZNF428 zinc finger protein 428
ZNF586 zinc finger protein 586
ZNF74 zinc finger protein 74
ZNF767P zinc finger family member 767, pseudogene