drosha Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description drosha, ribonuclease type III|Members of the ribonuclease III superfamily of double-stranded (ds) RNA-specific endoribonucleases participate in diverse RNA maturation and decay pathways in eukaryotic and prokaryotic cells (Fortin et al., 2002 [PubMed 12191433]). The RNase III Drosha is the core nuclease that executes the initiation step of microRNA (miRNA) processing in the nucleus (Lee et al., 2003 [PubMed 14508493]).[supplied by OMIM, Mar 2008] (NCBI Entrez Gene Database, 29102)
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Genes

27 genes co-occuring with the biological term drosha in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AFF1 AF4/FMR2 family, member 1
AGO1 argonaute RISC catalytic component 1
AGO2 argonaute RISC catalytic component 2
AURKB aurora kinase B
BRCA1 breast cancer 1, early onset
DGCR8 DGCR8 microprocessor complex subunit
DICER1 dicer 1, ribonuclease type III
DROSHA drosha, ribonuclease type III
E2F1 E2F transcription factor 1
FUS FUS RNA binding protein
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
KHSRP KH-type splicing regulatory protein
KMT2A lysine (K)-specific methyltransferase 2A
MIR18A microRNA 18a
MIR21 microRNA 21
MIR27B microRNA 27b
MIR630 microRNA 630
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
PTEN phosphatase and tensin homolog
RNH1 ribonuclease/angiogenin inhibitor 1
SBDS Shwachman-Bodian-Diamond syndrome
SNIP1 Smad nuclear interacting protein 1
TARBP2 TAR (HIV-1) RNA binding protein 2
TARDBP TAR DNA binding protein
TP53 tumor protein p53
XPO5 exportin 5
ZNF512B zinc finger protein 512B