drotaverine Gene Set
Genes
18 genes differentially expressed following the drotaverine small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
WASHC4
|
WASH complex subunit 4
|
4.49278
|
|
COPS7A
|
COP9 signalosome subunit 7A
|
3.75607
|
|
SIRAL2
|
SIR2 antiphage like 2
|
3.46792
|
|
PCP4
|
Purkinje cell protein 4
|
3.33479
|
|
AMT
|
aminomethyltransferase
|
3.31406
|
|
AMD1
|
adenosylmethionine decarboxylase 1
|
3.18616
|
|
CASP10
|
caspase 10, apoptosis-related cysteine peptidase
|
3.12418
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
3.07369
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
E2F2
|
E2F transcription factor 2
|
-4.99679
|
|
RRAD
|
Ras-related associated with diabetes
|
-4.48356
|
|
MAGEB1
|
melanoma antigen family B1
|
-3.51492
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.27606
|
|
MAMLD1
|
mastermind-like domain containing 1
|
-3.1354
|
|
S100A3
|
S100 calcium binding protein A3
|
-3.04824
|
|
MAGEA1
|
melanoma antigen family A1
|
-3.04114
|
|
HAPLN2
|
hyaluronan and proteoglycan link protein 2
|
-3.02591
|
|
MAGEC1
|
melanoma antigen family C1
|
-3.01108
|
|
IL11
|
interleukin 11
|
-3.00775
|
