dyclonine-7423 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the dyclonine-7423 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ADCK2 aarF domain containing kinase 2
ADRBK1 adrenergic, beta, receptor kinase 1
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ANKRD12 ankyrin repeat domain 12
ARFRP1 ADP-ribosylation factor related protein 1
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATN1 atrophin 1
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
CAMK1 calcium/calmodulin-dependent protein kinase I
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDK20 cyclin-dependent kinase 20
CLDN15 claudin 15
CNTNAP2 contactin associated protein-like 2
CTNS cystinosin, lysosomal cystine transporter
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DGKE diacylglycerol kinase, epsilon 64kDa
DIEXF digestive organ expansion factor homolog (zebrafish)
DST dystonin
DUSP4 dual specificity phosphatase 4
EHBP1L1 EH domain binding protein 1-like 1
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
EPHB4 EPH receptor B4
FBXL15 F-box and leucine-rich repeat protein 15
FGFR1 fibroblast growth factor receptor 1
FGGY FGGY carbohydrate kinase domain containing
FLJ11292
FLT4 fms-related tyrosine kinase 4
FSTL3 follistatin-like 3 (secreted glycoprotein)
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GCLM glutamate-cysteine ligase, modifier subunit
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GID4 GID complex subunit 4
GPR137 G protein-coupled receptor 137
H2AFX H2A histone family, member X
HMOX1 heme oxygenase 1
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IL11 interleukin 11
IL15RA interleukin 15 receptor, alpha
INSR insulin receptor
KIF3C kinesin family member 3C
KRBOX4 KRAB box domain containing 4
KRT8 keratin 8, type II
LEPR leptin receptor
LOC399491
LRRC14 leucine rich repeat containing 14
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MIIP migration and invasion inhibitory protein
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MZF1 myeloid zinc finger 1
NDRG1 N-myc downstream regulated 1
OSGIN1 oxidative stress induced growth inhibitor 1
PACS1 phosphofurin acidic cluster sorting protein 1
PILRB paired immunoglobin-like type 2 receptor beta
PLAA phospholipase A2-activating protein
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
POFUT1 protein O-fucosyltransferase 1
PPAP2B phosphatidic acid phosphatase type 2B
PROL1 proline rich, lacrimal 1
PSG9 pregnancy specific beta-1-glycoprotein 9
RANBP3 RAN binding protein 3
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
SGPL1 sphingosine-1-phosphate lyase 1
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC25A40 solute carrier family 25, member 40
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SPTBN1 spectrin, beta, non-erythrocytic 1
STX7 syntaxin 7
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TBX19 T-box 19
TMCO1 transmembrane and coiled-coil domains 1
TMCO3 transmembrane and coiled-coil domains 3
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TPD52 tumor protein D52
TTC23 tetratricopeptide repeat domain 23
TXNRD1 thioredoxin reductase 1
USP27X ubiquitin specific peptidase 27, X-linked
USP34 ubiquitin specific peptidase 34
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WDR19 WD repeat domain 19
WDR48 WD repeat domain 48
WSCD1 WSC domain containing 1
ZFHX2 zinc finger homeobox 2
ZNF141 zinc finger protein 141
ZNF202 zinc finger protein 202
ZNF446 zinc finger protein 446
ZNF473 zinc finger protein 473
ZNF609 zinc finger protein 609
ZNF839 zinc finger protein 839
ZSCAN32 zinc finger and SCAN domain containing 32

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKRD40 ankyrin repeat domain 40
ARHGAP10 Rho GTPase activating protein 10
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ASB7 ankyrin repeat and SOCS box containing 7
ASTE1 asteroid homolog 1 (Drosophila)
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
AUH AU RNA binding protein/enoyl-CoA hydratase
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BBS1 Bardet-Biedl syndrome 1
BCAS1 breast carcinoma amplified sequence 1
BIK BCL2-interacting killer (apoptosis-inducing)
BMP4 bone morphogenetic protein 4
C17ORF70 chromosome 17 open reading frame 70
C19ORF40 chromosome 19 open reading frame 40
CAMKMT calmodulin-lysine N-methyltransferase
CARD8 caspase recruitment domain family, member 8
CCDC85C coiled-coil domain containing 85C
CERK ceramide kinase
CGREF1 cell growth regulator with EF-hand domain 1
CHST10 carbohydrate sulfotransferase 10
CISH cytokine inducible SH2-containing protein
CLSPN claspin
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
COPZ1 coatomer protein complex, subunit zeta 1
DEAF1 DEAF1 transcription factor
EFNA1 ephrin-A1
EFNA4 ephrin-A4
FAM131A family with sequence similarity 131, member A
FAM50B family with sequence similarity 50, member B
FAN1 FANCD2/FANCI-associated nuclease 1
FBXL6 F-box and leucine-rich repeat protein 6
FPGS folylpolyglutamate synthase
FURIN furin (paired basic amino acid cleaving enzyme)
GCHFR GTP cyclohydrolase I feedback regulator
GJA1 gap junction protein, alpha 1, 43kDa
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GRB7 growth factor receptor-bound protein 7
GRWD1 glutamate-rich WD repeat containing 1
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4
HLA-J major histocompatibility complex, class I, J (pseudogene)
INCENP inner centromere protein antigens 135/155kDa
IRF7 interferon regulatory factor 7
IRF9 interferon regulatory factor 9
JUNB jun B proto-oncogene
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LPPR2 lipid phosphate phosphatase-related protein type 2
LRRC8E leucine rich repeat containing 8 family, member E
MAGEH1 melanoma antigen family H1
MED15 mediator complex subunit 15
MEIS2 Meis homeobox 2
MGC12488
MICALL2 MICAL-like 2
MYLIP myosin regulatory light chain interacting protein
NBEAL2 neurobeachin-like 2
ONECUT2 one cut homeobox 2
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNF126P1 ring finger protein 126 pseudogene 1
RPAP1 RNA polymerase II associated protein 1
RPUSD2 RNA pseudouridylate synthase domain containing 2
SCD5 stearoyl-CoA desaturase 5
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SETD1A SET domain containing 1A
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SH2D4A SH2 domain containing 4A
SIRT6 sirtuin 6
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SNRPC small nuclear ribonucleoprotein polypeptide C
SP140L SP140 nuclear body protein-like
SPINK4 serine peptidase inhibitor, Kazal type 4
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STX17 syntaxin 17
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TCTA T-cell leukemia translocation altered
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMEM53 transmembrane protein 53
TMUB2 transmembrane and ubiquitin-like domain containing 2
TPCN1 two pore segment channel 1
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TSPYL2 TSPY-like 2
TUBGCP5 tubulin, gamma complex associated protein 5
UBQLN4 ubiquilin 4
VAV1 vav 1 guanine nucleotide exchange factor
YEATS2 YEATS domain containing 2
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF205 zinc finger protein 205
ZNF586 zinc finger protein 586
ZNF629 zinc finger protein 629