dyclonine Gene Set

Dataset	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category	transcriptomics
Type	small molecule perturbation
Description	N-Ethylpiperidine in which one of the hydrogens attached to the methyl group is substituted by a 4-butoxybenzoyl group. (Chemical Entities of Biological Interest Ontology, CHEBI_4724)
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Genes

16 genes differentially expressed following the dyclonine small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol	Name	Standardized Value
COQ8A	coenzyme Q8A	5.42516
STUB1	STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase	3.96735
KLHDC2	kelch domain containing 2	3.69633
SERPINB8	serpin peptidase inhibitor, clade B (ovalbumin), member 8	3.15878
ECHDC3	enoyl CoA hydratase domain containing 3	3.05105

decreased expression

Symbol	Name	Standardized Value
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	-4.80977
RFX5	regulatory factor X, 5 (influences HLA class II expression)	-3.68633
PCNA	proliferating cell nuclear antigen	-3.66003
CANT1	calcium activated nucleotidase 1	-3.62105
OPRL1	opiate receptor-like 1	-3.60236
CDC25B	cell division cycle 25B	-3.47038
SIRT3	sirtuin 3	-3.20185
EDA	ectodysplasin A	-3.02462
SNORA21	small nucleolar RNA, H/ACA box 21	-3.02372
ATP8B4	ATPase, class I, type 8B, member 4	-3.0189
MAP7	microtubule-associated protein 7	-3.00395