dydrogesterone-2811 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the dydrogesterone-2811 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ALDOB aldolase B, fructose-bisphosphate
ALOX5 arachidonate 5-lipoxygenase
ALS2CL ALS2 C-terminal like
ANGPTL2 angiopoietin-like 2
ANKLE2 ankyrin repeat and LEM domain containing 2
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
ASGR2 asialoglycoprotein receptor 2
ATF6B activating transcription factor 6 beta
ATG10 autophagy related 10
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CAPN10 calpain 10
CD8A CD8a molecule
CIB2 calcium and integrin binding family member 2
CLDN11 claudin 11
CNOT2 CCR4-NOT transcription complex, subunit 2
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CTSF cathepsin F
CTSZ cathepsin Z
CXCR4 chemokine (C-X-C motif) receptor 4
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DOK4 docking protein 4
EDNRB endothelin receptor type B
FAM46C family with sequence similarity 46, member C
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FN1 fibronectin 1
FOXN3 forkhead box N3
FPR2 formyl peptide receptor 2
GFER growth factor, augmenter of liver regeneration
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GMPR guanosine monophosphate reductase
GRIK1 glutamate receptor, ionotropic, kainate 1
GRIK5 glutamate receptor, ionotropic, kainate 5
GYPB glycophorin B (MNS blood group)
HIRA histone cell cycle regulator
HLA-DMB major histocompatibility complex, class II, DM beta
ICA1 islet cell autoantigen 1, 69kDa
ICAM2 intercellular adhesion molecule 2
IDS iduronate 2-sulfatase
IL1RN interleukin 1 receptor antagonist
IL22 interleukin 22
ITM2C integral membrane protein 2C
KCNK10 potassium channel, two pore domain subfamily K, member 10
KIAA1324 KIAA1324
KRT2 keratin 2, type II
LATS1 large tumor suppressor kinase 1
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
LRP4 low density lipoprotein receptor-related protein 4
MEF2D myocyte enhancer factor 2D
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
NPPB natriuretic peptide B
OGFR opioid growth factor receptor
ONECUT2 one cut homeobox 2
PACS1 phosphofurin acidic cluster sorting protein 1
PAX5 paired box 5
PEX3 peroxisomal biogenesis factor 3
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLIN2 perilipin 2
PML promyelocytic leukemia
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
PTPRO protein tyrosine phosphatase, receptor type, O
PTRF polymerase I and transcript release factor
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RASA3 RAS p21 protein activator 3
RGS12 regulator of G-protein signaling 12
RHEB Ras homolog enriched in brain
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RYR1 ryanodine receptor 1 (skeletal)
RYR2 ryanodine receptor 2 (cardiac)
SBNO2 strawberry notch homolog 2 (Drosophila)
SCUBE3 signal peptide, CUB domain, EGF-like 3
SDC2 syndecan 2
SLC43A3 solute carrier family 43, member 3
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SPEG SPEG complex locus
SSTR4 somatostatin receptor 4
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
TAOK2 TAO kinase 2
TAPT1 transmembrane anterior posterior transformation 1
TBX5 T-box 5
TICAM1 toll-like receptor adaptor molecule 1
TLDC1 TBC/LysM-associated domain containing 1
TM4SF1 transmembrane 4 L six family member 1
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TPMT thiopurine S-methyltransferase
TRBC1 T cell receptor beta constant 1
TSC22D4 TSC22 domain family, member 4
TUBA3C tubulin, alpha 3c
USP46 ubiquitin specific peptidase 46
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VIM vimentin
VWA5A von Willebrand factor A domain containing 5A
XDH xanthine dehydrogenase
ZFP36L2 ZFP36 ring finger protein-like 2

decreased expression

Symbol Name
ACTN4 actinin, alpha 4
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
APOC1 apolipoprotein C-I
APOLD1 apolipoprotein L domain containing 1
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ATAD3A ATPase family, AAA domain containing 3A
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
BATF basic leucine zipper transcription factor, ATF-like
BCORL1 BCL6 corepressor-like 1
C11ORF95 chromosome 11 open reading frame 95
C17ORF70 chromosome 17 open reading frame 70
C7ORF43 chromosome 7 open reading frame 43
CAMTA2 calmodulin binding transcription activator 2
CBR4 carbonyl reductase 4
CBX8 chromobox homolog 8
CCDC15 coiled-coil domain containing 15
CDR2L cerebellar degeneration-related protein 2-like
CEP72 centrosomal protein 72kDa
CHMP6 charged multivesicular body protein 6
CRY2 cryptochrome circadian clock 2
CTC1 CTS telomere maintenance complex component 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EFHD2 EF-hand domain family, member D2
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
F2R coagulation factor II (thrombin) receptor
FAAH fatty acid amide hydrolase
FAM188A family with sequence similarity 188, member A
FBXL2 F-box and leucine-rich repeat protein 2
FBXO31 F-box protein 31
FCHO1 FCH domain only 1
FOXD1 forkhead box D1
FOXJ2 forkhead box J2
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GAMT guanidinoacetate N-methyltransferase
GLB1L2 galactosidase, beta 1-like 2
GMIP GEM interacting protein
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GRAMD3 GRAM domain containing 3
H1F0 H1 histone family, member 0
HIST1H2AI histone cluster 1, H2ai
IFT22 intraflagellar transport 22
IGSF1 immunoglobulin superfamily, member 1
INF2 inverted formin, FH2 and WH2 domain containing
JUNB jun B proto-oncogene
KIAA0125 KIAA0125
KPNA4 karyopherin alpha 4 (importin alpha 3)
KPNA5 karyopherin alpha 5 (importin alpha 6)
LY6D lymphocyte antigen 6 complex, locus D
LY6G5C lymphocyte antigen 6 complex, locus G5C
LYPD1 LY6/PLAUR domain containing 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MITF microphthalmia-associated transcription factor
MPPED2 metallophosphoesterase domain containing 2
MRPL4 mitochondrial ribosomal protein L4
MTCP1 mature T-cell proliferation 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MUM1 melanoma associated antigen (mutated) 1
MVD mevalonate (diphospho) decarboxylase
MXD3 MAX dimerization protein 3
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
NDRG4 NDRG family member 4
PCF11 PCF11 cleavage and polyadenylation factor subunit
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor
PER3 period circadian clock 3
PHF11 PHD finger protein 11
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLA2G10 phospholipase A2, group X
PLA2G3 phospholipase A2, group III
PRPH peripherin
QTRT1 queuine tRNA-ribosyltransferase 1
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RPL23AP32 ribosomal protein L23a pseudogene 32
SAYSD1 SAYSVFN motif domain containing 1
SCRN3 secernin 3
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SHPK sedoheptulokinase
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
TCTN1 tectonic family member 1
TIGAR TP53 induced glycolysis regulatory phosphatase
TMEM104 transmembrane protein 104
TMEM115 transmembrane protein 115
TMEM222 transmembrane protein 222
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
USB1 U6 snRNA biogenesis 1
WDR6 WD repeat domain 6
XYLT2 xylosyltransferase II
YIPF1 Yip1 domain family, member 1
ZNF134 zinc finger protein 134
ZNF165 zinc finger protein 165
ZNF331 zinc finger protein 331
ZNF365 zinc finger protein 365
ZNF492 zinc finger protein 492
ZNF532 zinc finger protein 532
ZNF862 zinc finger protein 862