dydrogesterone-4254 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the dydrogesterone-4254 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAN aggrecan
ACSBG1 acyl-CoA synthetase bubblegum family member 1
AKR1C2 aldo-keto reductase family 1, member C2
ANKRD7 ankyrin repeat domain 7
ANO2 anoctamin 2, calcium activated chloride channel
ARL14 ADP-ribosylation factor-like 14
ART1 ADP-ribosyltransferase 1
ASIC4 acid sensing (proton gated) ion channel family member 4
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BGN biglycan
BICD1 bicaudal D homolog 1 (Drosophila)
BMP7 bone morphogenetic protein 7
C19ORF73 chromosome 19 open reading frame 73
C22ORF24 chromosome 22 open reading frame 24
CA5B carbonic anhydrase VB, mitochondrial
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CCR7 chemokine (C-C motif) receptor 7
CD8B CD8b molecule
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CNTNAP2 contactin associated protein-like 2
CSF1 colony stimulating factor 1 (macrophage)
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CTRC chymotrypsin C (caldecrin)
CYBA cytochrome b-245, alpha polypeptide
DDIT4 DNA-damage-inducible transcript 4
DKFZP434L187 uncharacterized LOC26082
DRD2 dopamine receptor D2
ENO3 enolase 3 (beta, muscle)
EPN1 epsin 1
FAM63A family with sequence similarity 63, member A
FMO5 flavin containing monooxygenase 5
FOXN3 forkhead box N3
GAS7 growth arrest-specific 7
GEMIN8 gem (nuclear organelle) associated protein 8
GLB1L galactosidase, beta 1-like
GRB7 growth factor receptor-bound protein 7
HIST1H2AB histone cluster 1, H2ab
HPN hepsin
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
HTR7P1 5-hydroxytryptamine (serotonin) receptor 7 pseudogene 1
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGKC immunoglobulin kappa constant
IL12B interleukin 12B
ITGA7 integrin, alpha 7
JADE2 jade family PHD finger 2
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KCTD13 potassium channel tetramerization domain containing 13
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KRT12 keratin 12, type I
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
LINC00115 long intergenic non-protein coding RNA 115
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRRN2 leucine rich repeat neuronal 2
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAN1A2 mannosidase, alpha, class 1A, member 2
MAPK10 mitogen-activated protein kinase 10
MFAP3L microfibrillar-associated protein 3-like
MPZ myelin protein zero
MRC2 mannose receptor, C type 2
MST1 macrophage stimulating 1
NF1 neurofibromin 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NR5A2 nuclear receptor subfamily 5, group A, member 2
NRIP3 nuclear receptor interacting protein 3
ODAM odontogenic, ameloblast asssociated
ONECUT1 one cut homeobox 1
PCSK6 proprotein convertase subtilisin/kexin type 6
PEAK1 pseudopodium-enriched atypical kinase 1
PHF14 PHD finger protein 14
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLXDC1 plexin domain containing 1
PML promyelocytic leukemia
PNPLA3 patatin-like phospholipase domain containing 3
PTK2B protein tyrosine kinase 2 beta
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN21 protein tyrosine phosphatase, non-receptor type 21
RARB retinoic acid receptor, beta
RUNX1 runt-related transcription factor 1
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC6A16 solute carrier family 6, member 16
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SPINK5 serine peptidase inhibitor, Kazal type 5
SUGP1 SURP and G patch domain containing 1
TEX14 testis expressed 14
THBD thrombomodulin
THSD4 thrombospondin, type I, domain containing 4
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TPM3 tropomyosin 3
TPSB2 tryptase beta 2 (gene/pseudogene)
TTC9 tetratricopeptide repeat domain 9
ZNF155 zinc finger protein 155
ZNF747 zinc finger protein 747

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ACKR3 atypical chemokine receptor 3
ADAM23 ADAM metallopeptidase domain 23
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20
AFAP1 actin filament associated protein 1
AGMAT agmatine ureohydrolase (agmatinase)
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AIM2 absent in melanoma 2
AK5 adenylate kinase 5
ALOX12 arachidonate 12-lipoxygenase
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ARMCX4 armadillo repeat containing, X-linked 4
AXIN1 axin 1
BAHD1 bromo adjacent homology domain containing 1
C22ORF46 chromosome 22 open reading frame 46
C7ORF43 chromosome 7 open reading frame 43
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CBX4 chromobox homolog 4
CD82 CD82 molecule
CES3 carboxylesterase 3
CLCA1 chloride channel accessory 1
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CPNE7 copine VII
CXCR2 chemokine (C-X-C motif) receptor 2
CXORF21 chromosome X open reading frame 21
EGLN3 egl-9 family hypoxia-inducible factor 3
EGOT eosinophil granule ontogeny transcript (non-protein coding)
ELP6 elongator acetyltransferase complex subunit 6
FAM13C family with sequence similarity 13, member C
FGF20 fibroblast growth factor 20
FRS3 fibroblast growth factor receptor substrate 3
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GRAMD1C GRAM domain containing 1C
GREM1 gremlin 1, DAN family BMP antagonist
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HIST1H2AK histone cluster 1, H2ak
HIST1H2BN histone cluster 1, H2bn
HIST1H2BO histone cluster 1, H2bo
IDI2-AS1 IDI2 antisense RNA 1
IL36RN interleukin 36 receptor antagonist
IMPG1 interphotoreceptor matrix proteoglycan 1
IQSEC2 IQ motif and Sec7 domain 2
KANSL3 KAT8 regulatory NSL complex subunit 3
KIAA0754 KIAA0754
KIAA1107 KIAA1107
KIF13A kinesin family member 13A
KLHL25 kelch-like family member 25
LAX1 lymphocyte transmembrane adaptor 1
LIME1 Lck interacting transmembrane adaptor 1
LOC100287590 uncharacterized LOC100287590
LOXL3 lysyl oxidase-like 3
LRRC37A4P leucine rich repeat containing 37, member A4, pseudogene
LY6G6C lymphocyte antigen 6 complex, locus G6C
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
MTCP1 mature T-cell proliferation 1
MYO15A myosin XVA
MYOZ3 myozenin 3
NOTCH4 notch 4
NPIPB3 nuclear pore complex interacting protein family, member B3
OLFML2B olfactomedin-like 2B
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PARP11 poly (ADP-ribose) polymerase family, member 11
PLAC8 placenta-specific 8
PLBD1 phospholipase B domain containing 1
PLSCR2 phospholipid scramblase 2
PPL periplakin
PRKG2 protein kinase, cGMP-dependent, type II
PRM2 protamine 2
PRR4 proline rich 4 (lacrimal)
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PTPRH protein tyrosine phosphatase, receptor type, H
RABL6 RAB, member RAS oncogene family-like 6
SCD5 stearoyl-CoA desaturase 5
SCEL sciellin
SIX3 SIX homeobox 3
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SLMO1 slowmo homolog 1 (Drosophila)
STEAP4 STEAP family member 4
TBC1D22B TBC1 domain family, member 22B
TBKBP1 TBK1 binding protein 1
TIGD6 tigger transposable element derived 6
TLR2 toll-like receptor 2
TMEM40 transmembrane protein 40
TRAF2 TNF receptor-associated factor 2
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSNAXIP1 translin-associated factor X interacting protein 1
TTC12 tetratricopeptide repeat domain 12
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
VN1R1 vomeronasal 1 receptor 1
XYLT2 xylosyltransferase II
ZNF528 zinc finger protein 528
ZSCAN2 zinc finger and SCAN domain containing 2