dydrogesterone-4836 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the dydrogesterone-4836 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGFG2 ArfGAP with FG repeats 2
AGO4 argonaute RISC catalytic component 4
AJAP1 adherens junctions associated protein 1
AKAP11 A kinase (PRKA) anchor protein 11
ALMS1 Alstrom syndrome protein 1
AQP3 aquaporin 3 (Gill blood group)
ARL4C ADP-ribosylation factor-like 4C
ARMC4 armadillo repeat containing 4
ATF6B activating transcription factor 6 beta
ATM ATM serine/threonine kinase
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BDKRB2 bradykinin receptor B2
CC2D1A coiled-coil and C2 domain containing 1A
CCDC121 coiled-coil domain containing 121
CCDC88A coiled-coil domain containing 88A
CD1A CD1a molecule
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDH8 cadherin 8, type 2
CFDP1 craniofacial development protein 1
CFLAR CASP8 and FADD-like apoptosis regulator
CNTFR ciliary neurotrophic factor receptor
CNTNAP2 contactin associated protein-like 2
CPQ carboxypeptidase Q
DMTN dematin actin binding protein
DNAL4 dynein, axonemal, light chain 4
DPP4 dipeptidyl-peptidase 4
EDN1 endothelin 1
EFNA3 ephrin-A3
ELL elongation factor RNA polymerase II
ETAA1 Ewing tumor-associated antigen 1
EXOC7 exocyst complex component 7
FGFR1 fibroblast growth factor receptor 1
FHL1 four and a half LIM domains 1
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GPATCH2L G patch domain containing 2-like
GREB1 growth regulation by estrogen in breast cancer 1
HBS1L HBS1-like translational GTPase
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIST1H1E histone cluster 1, H1e
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IFI6 interferon, alpha-inducible protein 6
IFNA14 interferon, alpha 14
IFT27 intraflagellar transport 27
IGHA1 immunoglobulin heavy constant alpha 1
IRS2 insulin receptor substrate 2
ITGA7 integrin, alpha 7
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
JUN jun proto-oncogene
KDM4B lysine (K)-specific demethylase 4B
KIAA0319L KIAA0319-like
LMOD1 leiomodin 1 (smooth muscle)
MAN1A2 mannosidase, alpha, class 1A, member 2
MED18 mediator complex subunit 18
MFSD11 major facilitator superfamily domain containing 11
NAT6 N-acetyltransferase 6 (GCN5-related)
NFX1 nuclear transcription factor, X-box binding 1
NMT1 N-myristoyltransferase 1
NRF1 nuclear respiratory factor 1
OCA2 oculocutaneous albinism II
PARD6B par-6 family cell polarity regulator beta
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PSD3 pleckstrin and Sec7 domain containing 3
QKI QKI, KH domain containing, RNA binding
RAB6B RAB6B, member RAS oncogene family
RABGAP1 RAB GTPase activating protein 1
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RBM17 RNA binding motif protein 17
RBM3 RNA binding motif (RNP1, RRM) protein 3
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RUNX3 runt-related transcription factor 3
S100A8 S100 calcium binding protein A8
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SIK2 salt-inducible kinase 2
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SNX13 sorting nexin 13
SRSF1 serine/arginine-rich splicing factor 1
STS steroid sulfatase (microsomal), isozyme S
TJAP1 tight junction associated protein 1 (peripheral)
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TP53I11 tumor protein p53 inducible protein 11
TPCN1 two pore segment channel 1
TPR translocated promoter region, nuclear basket protein
TRBC1 T cell receptor beta constant 1
TUBBP5 tubulin, beta pseudogene 5
UBOX5 U-box domain containing 5
UHRF1BP1L UHRF1 binding protein 1-like
WDR76 WD repeat domain 76
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
XYLB xylulokinase homolog (H. influenzae)
ZNF442 zinc finger protein 442
ZNF609 zinc finger protein 609
ZNF652 zinc finger protein 652

decreased expression

Symbol Name
AFAP1 actin filament associated protein 1
AKAP12 A kinase (PRKA) anchor protein 12
AMT aminomethyltransferase
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ATAT1 alpha tubulin acetyltransferase 1
AUTS2 autism susceptibility candidate 2
BATF basic leucine zipper transcription factor, ATF-like
C11ORF63 chromosome 11 open reading frame 63
C17ORF80 chromosome 17 open reading frame 80
C1ORF21 chromosome 1 open reading frame 21
C5 complement component 5
CAPN5 calpain 5
CCDC85C coiled-coil domain containing 85C
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CDON cell adhesion associated, oncogene regulated
CHKB choline kinase beta
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CNGB3 cyclic nucleotide gated channel beta 3
COQ3 coenzyme Q3 methyltransferase
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DCLRE1A DNA cross-link repair 1A
DEAF1 DEAF1 transcription factor
EMID1 EMI domain containing 1
ERCC2 excision repair cross-complementation group 2
FAM120C family with sequence similarity 120C
FBXO31 F-box protein 31
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FGD6 FYVE, RhoGEF and PH domain containing 6
FRK fyn-related Src family tyrosine kinase
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNA13 guanine nucleotide binding protein (G protein), alpha 13
HDAC7 histone deacetylase 7
HIST1H2AI histone cluster 1, H2ai
HIST1H2BO histone cluster 1, H2bo
HMOX1 heme oxygenase 1
HYAL3 hyaluronoglucosaminidase 3
IL2 interleukin 2
INCENP inner centromere protein antigens 135/155kDa
IPO8 importin 8
KLHL28 kelch-like family member 28
KRT13 keratin 13, type I
LARP6 La ribonucleoprotein domain family, member 6
LRRC61 leucine rich repeat containing 61
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MCOLN3 mucolipin 3
MTMR11 myotubularin related protein 11
MTSS1L metastasis suppressor 1-like
NACA2 nascent polypeptide-associated complex alpha subunit 2
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
OTUD3 OTU deubiquitinase 3
P3H1 prolyl 3-hydroxylase 1
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PER3 period circadian clock 3
PGBD5 piggyBac transposable element derived 5
PGP phosphoglycolate phosphatase
PLA2G3 phospholipase A2, group III
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PRODH proline dehydrogenase (oxidase) 1
PRSS16 protease, serine, 16 (thymus)
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RHBG Rh family, B glycoprotein (gene/pseudogene)
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RPL23AP32 ribosomal protein L23a pseudogene 32
SAYSD1 SAYSVFN motif domain containing 1
SCHIP1 schwannomin interacting protein 1
SCMH1 sex comb on midleg homolog 1 (Drosophila)
SETD8 SET domain containing (lysine methyltransferase) 8
SIRT6 sirtuin 6
SLC17A2 solute carrier family 17, member 2
SMR3A submaxillary gland androgen regulated protein 3A
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STRA6 stimulated by retinoic acid 6
STX1A syntaxin 1A (brain)
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TBC1D17 TBC1 domain family, member 17
TCHH trichohyalin
TCTN1 tectonic family member 1
TEX40 testis expressed 40
TFF2 trefoil factor 2
TM6SF1 transmembrane 6 superfamily member 1
TMEM120B transmembrane protein 120B
TMEM212 transmembrane protein 212
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TNS2 tensin 2
TRAIP TRAF interacting protein
TTBK2 tau tubulin kinase 2
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UBQLN4 ubiquilin 4
UPK2 uroplakin 2
USB1 U6 snRNA biogenesis 1
VASH2 vasohibin 2
WDR4 WD repeat domain 4
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZNF180 zinc finger protein 180
ZNF8 zinc finger protein 8
ZNF804A zinc finger protein 804A