dysfunctional Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

120 genes co-occuring with the biological term dysfunctional in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACD adrenocortical dysplasia homolog (mouse)
ADAM19 ADAM metallopeptidase domain 19
ADIPOQ adiponectin, C1Q and collagen domain containing
AMPD1 adenosine monophosphate deaminase 1
APOA1 apolipoprotein A-I
APOC3 apolipoprotein C-III
APP amyloid beta (A4) precursor protein
ATM ATM serine/threonine kinase
ATR ATR serine/threonine kinase
BCL2 B-cell CLL/lymphoma 2
BDNF brain-derived neurotrophic factor
BRCA1 breast cancer 1, early onset
CADM1 cell adhesion molecule 1
CALB1 calbindin 1, 28kDa
CASP8 caspase 8, apoptosis-related cysteine peptidase
CAV3 caveolin 3
CDC25C cell division cycle 25C
CES1 carboxylesterase 1
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
COMT catechol-O-methyltransferase
CORIN corin, serine peptidase
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CUL4A cullin 4A
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCR4 chemokine (C-X-C motif) receptor 4
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DCT dopachrome tautomerase
DKK1 dickkopf WNT signaling pathway inhibitor 1
EDN1 endothelin 1
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ESR1 estrogen receptor 1
F7 coagulation factor VII (serum prothrombin conversion accelerator)
F9 coagulation factor IX
FAAH fatty acid amide hydrolase
FGA fibrinogen alpha chain
FOXC1 forkhead box C1
FST follistatin
GJC2 gap junction protein, gamma 2, 47kDa
GLS glutaminase
HAVCR2 hepatitis A virus cellular receptor 2
HDLC3 High density lipoprotein cholesterol, low serum, 3
HLA-DOA major histocompatibility complex, class II, DO alpha
HMOX1 heme oxygenase 1
HMOX2 heme oxygenase 2
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTT huntingtin
IGF1 insulin-like growth factor 1 (somatomedin C)
IL1A interleukin 1, alpha
IL1RN interleukin 1 receptor antagonist
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KDR kinase insert domain receptor
KIAA1524 KIAA1524
KLF2 Kruppel-like factor 2
LMNA lamin A/C
LRPPRC leucine-rich pentatricopeptide repeat containing
MIR106B microRNA 106b
MIR17 microRNA 17
MIR204 microRNA 204
MIR379 microRNA 379
MITF microphthalmia-associated transcription factor
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUTYH mutY homolog
MYC v-myc avian myelocytomatosis viral oncogene homolog
NEIL1 nei endonuclease VIII-like 1 (E. coli)
NKX2-5 NK2 homeobox 5
NOS3 nitric oxide synthase 3 (endothelial cell)
NPPB natriuretic peptide B
OXTR oxytocin receptor
PARK2 parkin RBR E3 ubiquitin protein ligase
PDCD1 programmed cell death 1
PEX7 peroxisomal biogenesis factor 7
PHB prohibitin
PINK1 PTEN induced putative kinase 1
PLAT plasminogen activator, tissue
PLK2 polo-like kinase 2
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PRKG1 protein kinase, cGMP-dependent, type I
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
RAD51 RAD51 recombinase
REST RE1-silencing transcription factor
RTN4R reticulon 4 receptor
S100A10 S100 calcium binding protein A10
SAA2 serum amyloid A2
SCARB1 scavenger receptor class B, member 1
SCN1A sodium channel, voltage gated, type I alpha subunit
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SCNN1B sodium channel, non voltage gated 1 beta subunit
SCNN1G sodium channel, non voltage gated 1 gamma subunit
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SFTPB surfactant protein B
SFTPC surfactant protein C
SIGLEC7 sialic acid binding Ig-like lectin 7
SIRT1 sirtuin 1
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SP1 Sp1 transcription factor
SREBF1 sterol regulatory element binding transcription factor 1
ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3
STX4 syntaxin 4
TBX21 T-box 21
TERC telomerase RNA component
TERT telomerase reverse transcriptase
TFAM transcription factor A, mitochondrial
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TLR1 toll-like receptor 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR9 toll-like receptor 9
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TP53 tumor protein p53
TREX1 three prime repair exonuclease 1
TYR tyrosinase
TYRP1 tyrosinase-related protein 1
VEGFA vascular endothelial growth factor A
VTCN1 V-set domain containing T cell activation inhibitor 1